• n.
  • 明らかにする/なること。(通例 -s)明示。現れ。(霊の)出現
  • (政府・政党などの)政策表明。(政治的な)示威運動
  • 病気の徴候/症状



  1. a clear appearance; "a manifestation of great emotion"
  2. a manifest indication of the existence or presence or nature of some person or thing; "a manifestation of disease"
  3. place signs, as along a road; "sign an intersection"; "This road has been signed"
  4. (medicine) any objective evidence of the presence of a disorder or disease; "there were no signs of asphyxiation"
  5. a perceptible indication of something not immediately apparent (as a visible clue that something has happened); "he showed signs of strain"; "they welcomed the signs of spring" (同)mark
  6. a character indicating a relation between quantities; "dont forget the minus sign"
  7. a fundamental linguistic unit linking a signifier to that which is signified; "The bond between the signifier and the signified is arbitrary"--de Saussure
  8. a gesture that is part of a sign language
  9. a public display of a message; "he posted signs in all the shop windows"
  10. engage by written agreement; "They signed two new pitchers for the next season" (同)contract, sign on, sign_up
  11. approve and express assent, responsibility, or obligation; "All parties ratified the peace treaty"; "Have you signed your contract yet?" (同)ratify
  12. communicate silently and non-verbally by signals or signs; "He signed his disapproval with a dismissive hand gesture"; "The diner signaled the waiters to bring the menu" (同)signal, signalize, signalise
  13. mark with ones signature; write ones name (on); "She signed the letter and sent it off"; "Please sign here" (同)subscribe
  14. be engaged by a written agreement; "He signed to play the casino on Dec. 18"; "The soprano signed to sing the new opera"
  15. communicate in sign language; "I dont know how to sign, so I could not communicate with my deaf cousin"
  16. without unnecessary stops; "an express train"; "an express shipment"
  17. rapid transport of goods (同)expressage
  18. public transport consisting of a fast train or bus that makes only a few scheduled stops; "he caught the express to New York" (同)limited
  19. mail that is distributed by a rapid and efficient system (同)express mail
  20. give expression to; "She showed her disappointment" (同)show, evince
  21. indicate through a symbol, formula, etc.; "Can you express this distance in kilometers?" (同)state
  22. articulate; either verbally or with a cry, shout, or noise; "She expressed her anger"; "He uttered a curse" (同)verbalize, verbalise, utter, give tongue to
  23. by express; "please send the letter express"
  24. manifest the effects of (a gene or genetic trait); "Many of the laboratory animals express the trait"
  25. not tacit or implied; "her express wish"
  26. send by rapid transport or special messenger service; "She expressed the letter to Florida"
  27. present oneself formally, as before a (judicial) authority; "He had to appear in court last month"; "She appeared on several charges of theft"
  28. come into being or existence, or appear on the scene; "Then the computer came along and changed our lives"; "Homo sapiens appeared millions of years ago" (同)come along
  29. be issued or published; "Did your latest book appear yet?"; "The new Woody Allen film hasnt come out yet" (同)come_out
  30. seem to be true, probable, or apparent; "It seems that he is very gifted"; "It appears that the weather in California is very bad" (同)seem
  31. appear as a character on stage or appear in a play, etc.; "Gielgud appears briefly in this movie"; "She appeared in `Hamlet on the London stage"
  32. come into sight or view; "He suddenly appeared at the wedding"; "A new star appeared on the horizon"
  33. reveal its presence or make an appearance; "the ghost manifests each year on the same day"
  34. a customs document listing the contents put on a ship or plane
  35. record in a ships manifest; "each passenger must be manifested"


  1. 〈U〉表明,明示;現れ,表現;〈C〉表明されたこと / 〈C〉(霊魂などの)出現
  2. (ある事実・状態・感情などの)『表れ』,印,気配,徴侯(indication);(…の)こん跡,計跡《+『of』+『名』》・『身ぶり』,手まね,合図 / 『標識』,看板 / (数学・音楽などの)記号 / (…の)『象徴』,シンボル(symbol)《+『of』+『名』》・《文》(…の)『前兆』,きざし《+『of』+『名』》・宮(きゅう)(黄道12区分の一つ) ・〈手紙・書類・作品など〉‘に'『署名する』・(…に)〈名前など〉‘を'書く《+『名』+『on』(『to』)+『名』》 / …‘を'雇う契約に署名する・…‘を'合図する,知らせる;…に合図する・署名する・契約書に署名して雇われる
  3. (言葉で)〈思想・感情など〉‘を'『表現する』,言い表す,述べる / (言葉以外で)…‘を'『示す』,表す(indicate);〈数字・記号・式などが〉…‘を'表す / 《英》〈荷物など〉‘を'至急便で送る / (…から)〈果汁など〉‘を'絞り出す《+『名』+『from』+『名』》 / 特別の,特定の / はっきりした,明白な / 『至急便の』,急行の / 至急便で,急行で / 〈U〉(手紙・荷物などの)『至急便』 / 〈C〉(至急便を扱う)通運会社 / 〈C〉(列車・バスなどの)『急行』
  4. 『姿を現す』,出現する / 〈本・記事などが〉公になる,出版される / (劇などに)出演する;(法廷などに)出廷する,出頭する / (…のように)『見える』,『思われる』
  5. 『明白な』,はっきりした(clear) / …‘を'『はっきり表す』(『示す』),表明する・(税関に提出するための船・飛行機の)積み荷目録;乗客名簿・宣言・声明書・檄文・特に,共産党宣言・政策綱領(イギリスの選挙で政党から公表されるもので,具体性を欠く選挙スローガンや公約と異なり,政策の数値目標,実施期限,財源などを明示する)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/09/28 18:58:22」(JST)

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English Journal

  • Human pleural B-cells regulate IFN-γ production by local T-cells and NK cells in a Mycobacterium tuberculosis-induced delayed hypersensitivity reaction.
  • Schierloh P1, Landoni V1, Balboa L1, Musella RM2, Castagnino J2, Moraña E3, de Casado GC, Palmero D2, Sasiain MC1.
  • Clinical science (London, England : 1979).Clin Sci (Lond).2014 Sep 1;127(6):391-403. doi: 10.1042/CS20130769.
  • DTH (delayed type hypersensitivity) reactions are secondary cellular immune responses that appear 24-72 h after antigen exposure. Tuberculous pleurisy is a common manifestation of extrapulmonary TB (tuberculosis) and is considered a human model of Th1-mediated DTH. In order to identify functional
  • PMID 24689690
  • How does ASD symptomology correlate with ADHD presentations?
  • Konst MJ1, Matson JL2, Goldin R2, Rieske R2.
  • Research in developmental disabilities.Res Dev Disabil.2014 Sep;35(9):2252-9. doi: 10.1016/j.ridd.2014.05.017. Epub 2014 Jun 12.
  • Elevated rates of attention deficit/hyperactivity disorder (ADHD) symptoms have been documented in the autism spectrum disorder (ASD) population. However, the recent restructuring of the ASD diagnostic category and its respective symptom structure has elicited concern about how these changes may imp
  • PMID 24929307
  • The mediating role of non-suicidal self-injury in the relationship between impulsivity and suicidal behavior among inpatients receiving treatment for substance use disorders.
  • Anestis MD1, Tull MT2, Lavender JM3, Gratz KL2.
  • Psychiatry research.Psychiatry Res.2014 Aug 15;218(1-2):166-73. doi: 10.1016/j.psychres.2014.03.031. Epub 2014 Apr 3.
  • Several theories posit a direct role of impulsivity in suicidal behavior. The interpersonal-psychological theory of suicidal behavior (IPTS) argues that the relationship between impulsivity and suicidal behavior is explained by the painful and/or provocative experiences (PPEs) often encountered by i
  • PMID 24768248
  • Personality organization in borderline patients with a history of suicide attempts.
  • Baus N1, Fischer-Kern M2, Naderer A2, Klein J2, Doering S2, Pastner B2, Leithner-Dziubas K2, Plener PL3, Kapusta ND2.
  • Psychiatry research.Psychiatry Res.2014 Aug 15;218(1-2):129-33. doi: 10.1016/j.psychres.2014.03.048. Epub 2014 Apr 5.
  • Suicide attempts (SA) are common in patients with Borderline Personality Disorder (BPD). Recent studies focus on aspects of personality associated with risk for SA such as deficits in affect regulation including impulse control and aggression. The current study examines associations of dysfunctional
  • PMID 24746393

Japanese Journal

  • Being and Aesthetic : Poetic Wisdom as The Manifestation of A Culture's Power to Live
  • Peng Shuixiang
  • Asian journal of social sciences & humanities 3(2), 22-29, 2014-05
  • NAID 40020084862
  • Longitudinal Study on Respiratory Viral Co-Infections in the Presence or Absence of Clinical Manifestation in Infants Aged 0-2 Years
  • Kawabuchi-Kurata Takako,Misaki Takako,Suehiro Yutaka [他]
  • Japanese Journal of Infectious Diseases 67(3), 216-220, 2014-05
  • NAID 40020072234
  • 顕微鏡的多発血管炎の病態,肺病変の特徴,治療 (特集 肺血管炎の基礎と臨床)
  • 穂積 宏尚,須田 隆文
  • 呼吸器内科 25(4), 294-302, 2014-04
  • NAID 40020086045
  • 下顎頭への転移を初発症状とした肝細胞癌の1例
  • 加藤 晃一郎,森家 祥行
  • 日本口腔外科学会雑誌 = Japanese journal of oral and maxillofacial surgery 60(4), 240-244, 2014-04
  • NAID 40020072233

Related Links

manifestationとは。意味や和訳。[名][U][C]((形式))1 明示,表明;顕示;現れ,表現;(病気の)徴候Art is a manifestation of emotion.芸術は感情の表現だ.2 (政治的な)示威運動,デモ.3 心霊物質化現象,(霊魂の)顕現. - goo辞書 ...
/mnfisteacute;in | -fes-/[名][U][C]((形式))1 明示, 表明;顕示;現れ, 表現;(病気の)徴候Art is a manifestation of emotion.|芸術は感情の表現だ.2 (政治的...
manifestationの意味は?goo辞書は無料で使える日本最大級の辞書サービスです。国語辞典、英和辞典、和英辞典、類語辞典、中国語辞典、百科事典などを提供しています。 ... ヘレン・ケラー 名言一覧 | Wiki 世界で最も素晴らしく、最も ...

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Les manifestations, qu’ossa donne? in Hooping as a Tool for Manifestation est ça la France ! » manifestation CGTÀ placer à votre agenda : Manifestation Fichier:20090129 paris manifestation.jpgmanifestationTag Archives: manifestationmanifestation

リンク元100Cases 33」「manifest」「appear」「finding」「indication
拡張検索initial manifestation

100Cases 33」


☆case33 頭痛と混乱
slurred n. 不明瞭
強直間代痙攣 tonic-clonic convulsion
 意識消失とともに全身随意筋強直痙攣が生じ(強直痙攣tonic convulsion)、次いで全身の筋の強直弛緩とが律動的に繰り返される時期(間代痙攣clonic convulsion)を経て、発作後もうろう状態を呈する一連発作
28歳、女性 黒人 南アフリカ 手術室看護師 ロンドン住在
診察 examination
やせている。55kg。38.5℃。口腔カンジダ症(oral candidiasis)。リンパ節腫脹無し。心血管呼吸器系、消化器系正常。痙攣前における神経検査では時間場所、人の見当識無し。神経局所症状無し(no focal neurological sign)。眼底両側に乳頭浮腫有り。
検査 investigation
口腔カンジダ症(oral candidiasis)
口腔カンジダ症(oral candidiasis) → 細胞免疫低下状態(DM免疫抑制AIDSなど) or 常在細菌叢の攪乱(長期抗菌薬の使用)
 ・The occurrence of thrush in a young, otherwise healthy-appearing person should prompt an investigation for underlying HIV infection.(HIM.1254)
 ・More commonly, thrush is seen as a nonspecific manifestation of severe debilitating illness.(HIM.1254)
精神症状強直間代痙攣 → 一次的、あるいは二次的な脳の疾患がありそう
頭痛 → 漠然としていて絞れないが、他の症状からして機能性頭痛ではなく症候性頭痛っぽい。
・眼底両側に乳頭浮腫 → 脳圧亢進徴候 → 原因は・・・脳腫瘍、ことにテント下腫瘍側頭葉腫瘍クモ膜下出血、脳水腫など、そのほか、眼窩内病変、低眼圧などの局所的要因、悪性高血圧、血液疾患大量出血肺気腫などの全身的要因 (vindicate本のp342も参考になる)
 ・頭痛脳圧亢進 → 頭蓋内圧占拠性病変脳炎(IMD.274)
CT所見 → ringform病変脳浮腫脳圧亢進
・低ナトリウム血症 → 脳ヘルニア続発して起こることがあるらしい。実際には下垂体トキソプラズマによる病変形成されることにより起こりうる。
パターン認識HIV + 精神症状 + てんかん発作(強直間代痙攣) + 脳圧亢進 + CT所見 = 一番ありそうなのはToxoplasma gondiiによるトキソプラズマ脳症 cerebral toxoplasosis (トキソプラズマ脳炎 toxoplasmic encephalitis)
Toxoplasma gondii
 原虫 胞子原虫
(感染予防学 080521のプリント、CASES p,92、HIM p.1305-)
 ・終宿主ネコネコ小腸上皮細胞で有性・無性生殖 糞便オーシスト排泄
病原病因 phathogenesis
 1. オーシスト経口摂取
 2. 中間宿主の生肉中のシスト経口摂取
 3. 初感染妊婦からの経胎盤感染。既感染なら胎盤感染しないらしい(HIM.1306)
 (4)移植臓器、輸血確率は低い(at low rate)(HIM.1306)
 1. 先天性トキソプラズマ症 congenital toxoplasmosis
   ①網脈絡膜炎、 ②水頭症、 ③脳内石灰化、 ④精神運動障害
 2. 後天性トキソプラズマ症 acquired toxoplasmosis
  (1) 健常者
   ・(少数例)筋肉痛、暈疼痛、腹痛、斑状丘疹状皮疹(maculopapular rash)、脳脊髄炎、混乱(HIM.1308)
   ・急性感染症状は数週間で消失 筋肉中枢神経系緩増虫体残存
   AIDSでは、トキソプラズマ脳炎が指標疾患 AIDS-defineing illness(CASES)
 (日本)アセチルスピラマイシンファンシダール(感染予防学 080521)
トキソプラズマ脳炎 toxoplasmic encephalitisトキソプラズマ脳症 cerebral toxoplasosis
 (CT,MRI)多発性両側性ring-enhancing lesion、特に灰白質-白質境界、大脳基底核脳幹小脳が冒されやすい(CASES)
このCTcerebral toxoplasmosis特徴的かは不明
 AIDSWBC(leukocyte)の数はどうなるんだろう???AIDSの初診患者ではWBCが低い人が多いらしいし()、HIVCD4+ T cellmacrophage感染して殺すから、これによってB cellは減るだろうし、CD8+ T cellも若干減少するだろうからWBCは減るんじゃないか?!好中球AIDSとは関係ない?好中球は他の感染症に反応性増加している?ちなみに、好酸球寄生虫(原虫)の感染のために増える傾向にあるらしい(HIMのどこか)。
スルファメトキサゾールトリメトプリム合剤 sulfamethoxazole and trimethoprim mixture
A CD4+ T-cell count below 200 cells/μl (or a CD4+ T-cell percentage of total lymphocytes of less than 14%).
or he/she has one of the following defining illnesses:
People who are not infected with HIV may also develop these conditions; this does not mean they have AIDS. However, when an individual presents laboratory evidence against HIV infection, a diagnosis of AIDS is ruled out unless the patient has not:
HIM = Harrison's Principles of Internal Medicine 17th Edition
CASES = 100 Cases in Clinical Medicine Second edition
IMD = 内科診断学第2版



  • adj.
  • 明白な、はんぜんとした、一目瞭然の。公知の。(精神分析)意識に現れた、顕在的な
  • vt.
  • 明らかにする、明示する。証明する。(行為などによって)(感情などを)表す
  • vi.
  • (幽霊などが)現れる
osteomyelitis classically manifests as an acute systemic illness with malaise, fever, leukocytosis, and throbbing pain over the affected region.
In PAN, renal involvement most commonly manifests as hypertension, renal insufficiency, or hemorrhage due to microaneurysms. (HIM.2125)(結節性多発動脈炎では、一般的に腎病変は高潔悦、腎不全あるいは微小血管瘤による出血として現れる)
  • n.
clarify, conspicuous, disclose, dominant, dramatic, elucidate, express, intense, manifestation, marked, markedly, notable, outstanding, overt, profound, remarkable, reveal, significant, striking, uncover, unmask




  • vi.
  • 見えてくる、現れる。発生/出現する、出る。出頭/出場/出演する(as)。
  • 明白である、はっきりしてくる。見たところ~らしい、~と思われる。
The ovarian hyperstimulation syndrome appears to be due to increased capillary permeability triggered by excessive release of one or more vasoactive substances secreted during maturation and luteinization of multiple follicles.(uptodate)(OHSSは、多数の卵胞が成熟し黄体となる過程で放出されるいくつかの血管作動性物質の過剰な放出が引き金となり、毛細血管の透過性が増加することによると思われる。)




  • n.
  • 見つけたこと、発見。[~s]発見物。(調べて)明らかになったこと[結論]
  • [~s](法律)(裁判官の)事実認定、(陪審員の)評決。(学者などの)研究結果、結論。(医学)(検死官・医師の)所見。(委員会の)答申
Findings on the frequency of injuries attributable to abuse versus accidents inthe first 36 months of life should be helpful for clinicians evaluating injuries in yound children.




  • n.
  • 指示、指摘、表示。しるし、兆し、徴候。(医)適応適応症


initial manifestation」


initial presentationinitial symptom