n.

破裂、破断、破壊。(医)破裂、断裂。(医)ヘルニア
決裂、断絶。仲違い、不和(between, with)

vt.

破る、裂く、破裂させる。断裂させる、決裂させる。仲たがいさせる
(医)～にヘルニアを起こさせる。

関: abolish、break、breakdown、burst、destroy、destruction、dismantle、disrupt、disruptant、disruption、explode、explosion、laceration、lesion、subversion、subvert

WordNet

state of being torn or burst open
the act of making a sudden noisy break
a personal or social separation (as between opposing factions); "they hoped to avoid a break in relations" (同)breach, break, severance, rift, falling out
prevent completion; "stop the project"; "break off the negotiations" (同)break off, discontinue, stop
happen; "Report the news as it develops"; "These political movements recrudesce from time to time" (同)recrudesce, develop
become separated into pieces or fragments; "The figurine broke"; "The freshly baked loaf fell apart" (同)separate, split up, fall_apart, come apart
be broken in; "If the new teacher wont break, well add some stress"
crack; of the male voice in puberty; "his voice is breaking--he should no longer sing in the choir"
destroy the integrity of; usually by force; cause to separate into pieces or fragments; "He broke the glass plate"; "She broke the match"
diminish or discontinue abruptly; "The patients fever broke last night"
fall sharply; "stock prices broke"
render inoperable or ineffective; "You broke the alarm clock when you took it apart!"
weaken or destroy in spirit or body; "His resistance was broken"; "a man broken by the terrible experience of near-death"
vary or interrupt a uniformity or continuity; "The flat plain was broken by tall mesas"
(tennis) a score consisting of winning a game when your opponent was serving; "he was up two breaks in the second set" (同)break of serve
an escape from jail; "the breakout was carefully planned" (同)breakout, jailbreak, gaolbreak, prisonbreak, prison-breaking
an act of delaying or interrupting the continuity; "it was presented without commercial breaks"; "there was a gap in his account" (同)interruption, disruption, gap
a sudden dash; "he made a break for the open door"
the opening shot that scatters the balls in billiards or pool
an unexpected piece of good luck; "he finally got his big break" (同)good_luck, happy chance
an abrupt change in the tone or register of the voice (as at puberty or due to emotion); "then there was a break in her voice"
the occurrence of breaking; "the break in the dam threatened the valley"
interrupt a continued activity; "She had broken with the traditional patterns" (同)break away
break a piece from a whole; "break a branch from a tree" (同)break off, snap off
move away or escape suddenly; "The horses broke from the stable"; "Three inmates broke jail"; "Nobody can break out--this prison is high security" (同)break_out, break away
destroy the completeness of a set of related items; "The book dealer would not break the set" (同)break_up
force out or release suddenly and often violently something pent up; "break into tears"; "erupt in anger" (同)burst, erupt
ruin completely; "He busted my radio!" (同)bust
be released or become known; of news; "News of her death broke in the morning" (同)get_out, get_around
go to pieces; "The lawn mower finally broke"; "The gears wore out"; "The old chair finally fell apart completely" (同)wear, wear_out, bust, fall_apart
become punctured or penetrated; "The skin broke"
cause the failure or ruin of; "His peccadilloes finally broke his marriage"; "This play will either make or break the playwright"
cause to give up a habit; "She finally broke herself of smoking cigarettes"
change directions suddenly
change suddenly from one tone quality or register to another; "Her voice broke to a whisper when she started to talk about her children"
come forth or begin from a state of latency; "The first winter storm broke over New York"
come into being; "light broke over the horizon"; "Voices broke in the air"
come to an end; "The heat wave finally broke yesterday"
curl over and fall apart in surf or foam, of waves; "The surf broke"
emerge from the surface of a body of water; "The whales broke"
exchange for smaller units of money; "I had to break a $100 bill just to buy the candy"
find a flaw in; "break an alibi"; "break down a proof"
find the solution or key to; "break the code"
give up; "break cigarette smoking"
happen or take place; "Things have been breaking pretty well for us in the past few months"
interrupt the flow of current in; "break a circuit"
invalidate by judicial action; "The will was broken"
make a rupture in the ranks of the enemy or ones own by quitting or fleeing; "The ranks broke"
make the opening shot that scatters the balls
pierce or penetrate; "The blade broke her skin"
scatter or part; "The clouds broke after the heavy downpour"
separate from a clinch, in boxing; "The referee broke the boxers"
undergo breaking; "The simple vowels broke in many Germanic languages"
show a violent emotional reaction; "The boss exploded when he heard of the resignation of the secretary"
burst outward, usually with noise; "The champagne bottle exploded" (同)burst
be unleashed; emerge with violence or noise; "His anger exploded" (同)burst forth, break loose
cause to burst with a violent release of energy; "We exploded the nuclear bomb" (同)detonate, blow_up, set_off
increase rapidly and in an uncontrolled manner; "The population of India is exploding"; "The islands rodent population irrupted" (同)irrupt
cause to burst as a result of air pressure; of stop consonants like /p/, /t/, and /k/
destroy by exploding; "The enemy exploded the bridge"
drive from the stage by noisy disapproval
show (a theory or claim) to be baseless, or refute and make obsolete
move suddenly, energetically, or violently; "He burst out of the house into the cool night"
break open or apart suddenly and forcefully; "The dam burst" (同)bust
come open suddenly and violently, as if from internal pressure; "The bubble burst" (同)split, break_open
a sudden flurry of activity (often for no obvious reason); "a burst of applause"; "a fit of housecleaning" (同)fit
emerge suddenly; "The sun burst into view"
the act of exploding or bursting; "the explosion of the firecrackers awoke the children"; "the burst of an atom bomb creates enormous radiation aloft" (同)burst
a golf shot from a bunker that typically moves sand as well as the golf ball
a violent release of energy caused by a chemical or nuclear reaction (同)detonation, blowup
a sudden great increase; "the population explosion"; "the information explosion"
a sudden outburst; "an explosion of laughter"; "an explosion of rage"
the noise caused by an explosion; "the explosion was heard a mile away"
common prostrate Old World herb often used as a ground cover; formerly reputed to cure ruptures (同)Hernaria glabra

PrepTutorEJDIC

〈U〉〈C〉(…の)破裂《+『of』+『名』》 / 〈U〉〈C〉(友好的関係などの)決裂,仲たがい / 〈C〉裂け目 / 〈C〉脱腸,ヘルニア / …‘を'破裂させる / 〈友好関係など〉‘を'断ち切る / 破裂する
…'を'『壊す』,割る,砕く;…'を'折る / …'を'擦りむく / …'を'『役に立たなくする』,壊す / (小さな物に)〈組になった物〉'を'分ける,ばらす,〈お金〉'を'くずす《+『名』+『into』+『名』》 / 〈垣・へいなど〉'を'破って出る / 〈法律・規則・約束など〉'を'『破る』,犯す / 〈均整・秩序・配列など〉'を'破る,くずす;〈持続しているもの〉'を'中止する,妨げる / 〈記録〉'を'破る,更新する / (…に)…'を'打ち明ける,知らせる《+『名』+『to』+『名』》 / …'を'破産させる,倒産させる / 〈気力・抵抗など〉'を'くじく;〈力・効果・強度〉'を'弱める / (…に)…‘の'位を下げる,…'を'降等させる《+『名』+『to』+『名』》 / 〈動物〉'を'ならす / 〈人〉‘の'(…の)癖を直す《+『名』〈人〉+『of』+『名』(do『ing』)》 / 〈暗号など〉'を'解読する;〈事件・問題など〉を解決する,解く / 《しばしば副詞[句]を伴って》『壊れる』,砕ける,割れる;破れる,破裂する / ぷっつりと切れる;中断する,途切れる;《米》仕事を中断する / はずれる,離れる,分離する《+『off』(『away』)》 / 故障する,壊れる,動かなくなる / 突然始まる;突然変化する / 夜が明ける / 〈健康・気力などが〉衰える,弱る;〈心が〉悲しみに打ちひしがれる / 〈株・価格などが〉急落する,暴落する / 壊れた箇所,裂け目,割れ目 / 中断,途切れ;不和,仲たがい / 休憩時間,小休止 / 逃亡計画,脱獄 / (…に向かっての)突進 / 急な変化,顕著な変化 / 夜明け / 《話》運,機会
〈火薬など爆発物が〉『爆発する』,破裂する / (怒り・笑いなどで)〈人が〉爆発する《+『with』(『in』)+『名』》 / 〈人口などが〉急激に増す / 〈物〉‘を'破裂させる;〈火薬など〉‘を'爆発させる / 〈習慣・迷信・学説など〉‘を'くつがえす,‘が'誤りであることを証明する
『破裂する』,爆発する / 〈つぼみが〉ほころびる / 《通例進行形で》(…で)はちきれそうにいっぱいである《+『with』+『名』》 / 『急に(…)する』 / …'を'破裂させる,爆発させる,破る / (…の)『破裂』,爆発《+『of』+『名』》 / (…の)『突発』《+『of』+『名』》
(火薬などの)『爆発』,破裂《+『of』+『名』》 / 爆発音 / 《an~》(怒り・笑いなどの)爆発《+『of』+『名』》 / 急激な増加

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/22 11:45:19」(JST)

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UpToDate Contents

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1. 妊娠満期に生じる前期破水による早産のマネージメント management of premature rupture of the fetal membranes at term
2. 成人における確定診断を得られていない低血圧やショックの評価および初期アプローチ evaluation of and initial approach to the adult patient with undifferentiated hypotension and shock
3. 大動脈解離のマネージメント management of aortic dissection
4. 妊娠中期の前期破水による早産 midtrimester preterm premature rupture of membranes
5. 大動脈峡部の外傷性破裂の経食道心エコー transesophageal echocardiography in traumatic rupture of the aortic isthmus

English Journal

[Cytological-energetic principle of the amniotic fluid examination on female patients with diagnosisof preterm premature rupture of membranes - up to now experiences and perspectives].

Müllerová K, Kelbich P, Švecová M.
Ceská gynekologie / Ceská lékarská spolecnost J. Ev. Purkyne.Ceska Gynekol.2016 Dec;80(6):414-20.
In our study we have dealt with the amniotic fluid examination on female patients with diagnosis of preterm premature rupture of membranes (PPROM). For one of the most important task in the feto-maternal medicine we consider the discovered method of amniotic fluid examination which is capable of the
PMID 26741155

Case-based discussion: an unusual manifestation of diaphragmatic hernia mimicking pneumothorax in an adult male.

Vyas PK1, Godbole C2, Bindroo SK3, Mathur RS3, Akula B2, Doctor N2.
International journal of emergency medicine.Int J Emerg Med.2016 Dec;9(1):11. doi: 10.1186/s12245-016-0108-5. Epub 2016 Feb 29.
Diaphragmatic hernia is an important cause of emergency hospital admission associated with significant morbidity. It usually results from congenital defect or rupture in the diaphragm due to trauma. Prompt and appropriate diagnosis is necessary in patients with this condition, as surgical interventi
PMID 26924754

Infective endocarditis of an aorto-right atrial fistula caused by asymptomatic rupture of a sinus of Valsalva aneurysm: a case report.

Ikeda A1, Nakajima T2, Konishi T2, Matsuzaki K2, Sugano A3, Fumikura Y3, Nishina H3, Jikuya T2.
Surgical case reports.Surg Case Rep.2016 Dec;2(1):43. doi: 10.1186/s40792-016-0171-4. Epub 2016 May 15.
Asymptomatic rupture of a sinus of Valsalva aneurysm is rare. A fistula following rupture of a sinus of Valsalva aneurysm may cause infective endocarditis. Here, we report a case of infective endocarditis of an aorto-right atrial fistula caused by asymptomatic rupture of a sinus of Valsalva aneurysm
PMID 27180251

Blunt cardiac injury: case report of salvaged traumatic right atrial rupture.

Al Ayyan M1, Aziz T1, El Sherif A1, Bekdache O1.
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES.Ulus Travma Acil Cerrahi Derg.2016 Nov;21(6):527-30. doi: 10.5505/tjtes.2016.12574.
The incidence of cardiac rupture following blunt trauma is rare, occurring in 0.3%-0.5% of all blunt trauma patients. It can be fatal at the trauma scene, and is frequently missed in the emergency room setting. The severity of a cardiac trauma is based on the mechanism and degree of the force applie
PMID 27054650

Japanese Journal

症例報告腹部大動脈瘤切迫破裂に対する人工血管置換術後に発症した後天性血栓性血小板減少性紫斑病

臨床血液 57(3), 364-368, 2016-03
NAID 40020791106

反対荷電イオン性ミセルの混合によるラメラ膜の形成機構(2)有効曲げ弾性とベシクルの破裂

九州共立大学総合研究所紀要 = Journal of Kyushu Kyoritsu University Research Center (9), 45-54, 2016-03
NAID 40020782678

ラットのアキレス腱修復に及ぼす直流鍼通電刺激の影響

宝塚医療大学紀要 = Proceedings of Takarazuka University of Medical and Health Care (3), 60-65, 2016-03
NAID 40020774202

野球による外傷性精巣破裂の1例

西日本泌尿器科 = The Nishinihon journal of urology 78(3), 122-125, 2016-03
NAID 40020768177

★リンクテーブル★

リンク元	「100Cases 16」「break」「abolish」「disrupt」「lesion」

「100Cases 16」

　　[★]

☆case16　膝の痛み

■glossary

indigestion 消化障害、消化不良

■症例

80歳　男性

主訴：左膝の痛みと腫脹

現病歴：左膝の痛みを2日前から認めた。膝は発熱・腫脹しており、動かすと疼痛を生じる。時々胸焼けと消化不良が見られる。6ヶ月前のhealth checkで、高血圧(172/102mmHg)と血中クレアチニンが高い(正常高値)こと以外は正常といわれた。その4週間数回血圧を測定したが、高値が継続したため、2.5mg bendrofluamethizide(UK)/ベンドロフルメチアジド bendroflumethiazide(US)で治療を開始した。最近の血圧は138/84 mmHgであった。

喫煙歴：なし。

飲酒歴：一週間に平均4unit。

既往歴：股関節に中程度(mild)の変形性関節症

家族歴：特記なし

服薬歴：アセトアミノフェン(股関節の疼痛に対して)

身体所見 examination

　血圧 142/86mmHg。体温37.5℃。脈拍88/分。grade 2 hypertensive retinopathy(高血圧症性網膜症)。心血管系、呼吸器系に検査場異常なし。手にDIPにヘバーデン結節なし。

　左膝が発熱し腫脹している。関節内に液、patellar tap陽性。90℃以上膝関節を屈曲させると痛みを生じる。右の膝関節は正常に見える。

検査　 investigation

　生化学：白血球増多、ESR 上昇、尿素高値、グルコース高値

　単純X線：関節間隙やや狭小。それ以外に異常は認めない。

■problem list

　#1 左膝の痛み

　#2 胸焼け

　#3 消化不良

　#4 高血圧

　#5 クレアチニン正常高値

　#6 股関節の変形性リウマチ

　#7 高血圧性網膜症

■考え方

　・関節痛の鑑別診断を考える。

　・VINDICATEで考えてみてもよいでしょう。

　・関節痛の頻度としては　外傷＞慢性疾患(OAなど)＞膠原病＞脊椎疾患＞悪性腫瘍

■関節痛の鑑別疾患

DIF 282

V Vascular 血友病 hemophilia, 壊血病 scurvy, 無菌性骨壊死 aseptic bone necrosis (Osgood-Schlatter diseaseとか)

I Inflammatory 淋疾 gonorrhea, ライム病 lyme disease, 黄色ブドウ球菌 Staphylococcus, 連鎖球菌 Streptococcus, 結核 tuberculosis, 梅毒 syphilis, 風疹 rubella, 単純ヘルペス herpes simplex, HIV human immunodeficiency virus, サイトメガロウイルス cytomegalovirus

N Neoplastic disorders 骨原性肉腫 osteogenic sarcoma, 巨細胞腫 giant cell tumors

D Degenerative disorders degenerative joint disease or 変形性関節症 osteoarthritis

I Intoxication 痛風 gout (uric acid), 偽痛風 pseudogout (calcium pyrophosphate), ループス症候群 lupus syndrome of hydralazine (Apresoline) and procainamide, gout syndrome of diuretics

C Congenital and acquired malformations bring to mind the joint deformities of tabes dorsalis and syringomyelia and congenital dislocation of the hip. Alkaptonuria is also considered here.