• n.
  • 取り扱い、待遇
  • 治療。(~の)治療法。対症療法
  • (問題の)論じ方。(芸術・文芸における)(題材・人物などの)配置、性格付け
  • (映画)(脚本の)流れ、場面構成
  • (化学薬品による)処理

application, care, clinical practice, cure, curing, handle, intervention, manipulate, manipulation, measure, medical care, practice, processing, remediation, remedy, therapeutic, therapeutics, therapy, transaction, treat



  1. the management of someone or something; "the handling of prisoners"; "the treatment of water sewage"; "the right to equal treatment in the criminal justice system" (同)handling
  2. care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury) (同)intervention
  3. a manner of dealing with something artistically; "his treatment of space borrows from Italian architecture"
  4. carry out or practice; as of jobs and professions; "practice law" (同)practise, exercise, do
  5. a customary way of operation or behavior; "it is their practice to give annual raises"; "they changed their dietary pattern" (同)pattern
  6. translating an idea into action; "a hard theory to put into practice"; "differences between theory and praxis of communism" (同)praxis
  7. the exercise of a profession; "the practice of the law"; "I took over his practice when he retired"
  8. knowledge of how something is usually done; "it is not the local practice to wear shorts to dinner"
  9. avail oneself to; "apply a principle"; "practice a religion"; "use care when going down the stairs"; "use your common sense"; "practice non-violent resistance" (同)apply, use
  10. feel concern or interest; "I really care about my work"; "I dont care"
  11. the work of providing treatment for or attending to someone or something; "no medical care was required"; "the old car needs constant attention" (同)attention, aid, tending
  12. attention and management implying responsibility for safety; "he is in the care of a bodyguard" (同)charge, tutelage, guardianship
  13. activity involved in maintaining something in good working order; "he wrote the manual on car care" (同)maintenance, upkeep
  14. a cause for feeling concern; "his major care was the illness of his wife"
  15. provide care for; "The nurse was caring for the wounded" (同)give care
  16. regard or consider in a specific way; "I treated his advances as a joke"
  17. provide treatment for; "The doctor treated my broken leg"; "The nurses cared for the bomb victims"; "The patient must be treated right away or she will die"; "Treat the infection with antibiotics" (同)care_for
  18. an occurrence that causes special pleasure or delight
  19. interact in a certain way; "Do right by her"; "Treat him with caution, please"; "Handle the press reporters gently" (同)handle, do by
  20. engage in negotiations in order to reach an agreement; "they had to treat with the King"
  21. provide with a gift or entertainment; "Grandmother always treated us to the circus"; "I like to treat myself to a day at a spa when I am depressed"
  22. the work of applying something; "the doctor prescribed a topical application of iodine"; "a complete bleach requires several applications"; "the surface was ready for a coating of paint"; (同)coating, covering
  23. a diligent effort; "it is a job requiring serious application" (同)diligence
  24. the act of bringing something to bear; using it for a particular purpose; "he advocated the application of statistics to the problem"; "a novel application of electronics to medical diagnosis" (同)practical application
  25. the action of putting something into operation; "the application of maximum thrust"; "massage has far-reaching medical applications"; "the application of indexes to tables of data"
  26. a program that gives a computer instructions that provide the user with tools to accomplish a task; "he has tried several different word processing applications" (同)application program, applications programme
  27. a verbal or written request for assistance or employment or admission to a school; "December 31 is the deadline for applications"


  1. 〈U〉(人・物の)『取り扱い』,扱い方《+of+名》 / 〈U〉治療;〈C〉(…に対する)治療法《+for+名》
  2. 〈U〉(絶えず繰り返す)『練習』,けいこ / 〈C〉〈U〉(1回の)練習の時間 / 〈U〉(練習で得た)熟練,腕前 / 〈U〉(理論に対して)(…の)『実行』,実施,実際《+『of』+『名』(do『ing』)》 / 〈C〉(…の)『習慣』,しきたり《+『of』+『名』(do『ing』)》 / 〈U〉(医師・弁護士などの)開業 / 〈C〉(医師・弁護士の)業務,仕事 / …‘を'『練習する』,けいこする / (習慣的に)…‘を'『実行する』,実践する / 〈弁護士・医師〉‘を'開業する / (…を)練習する,けいこをする《+『at』(『on, with』)+『名』(do『ing』)》 / (弁護士・医者として)開業する,開業している《+『as』+『名』》
  3. 〈U〉『心配』,気がかり,悩み / 〈C〉《しばしば複数形で》心配事,苦労の種 / 〈U〉『細心の注意』,十二分の用心 / 〈U〉(…の)『世話』,監督,保護《+『for(of)+名』》 / 〈C〉関心事,気を配るべきこと / 『気にする』,心配する,関心がある / …『したいと思う』,欲する,好む
  4. 《様態を表す副詞[句]を伴って》〈人・動物など〉‘を'『扱う』,待遇する・(…と)…‘を'『見なす』 (regard)《+名+as+名(形)》・〈問題など〉‘を'『扱う』,論じる・〈病人・病気など〉‘を'『治療する』,処理する・(化学薬品などで)…を処理する《+名+with+名》・(…を)〈人〉におごる,ごちそうする《+名〈人〉+to+名》・〈本・講義などが〉(問題などを)『扱う』,論じる《+of+名》・『おごる』,勘定をもつ・《文》(妥結・和解のために)(…と)交渉する,談判する《+with+名》・(思いがけなく)喜び(楽しみ)を与えてくれるもの・(めったにない)楽しみ・《one's treat》おごること,おごる番
  5. 〈U〉(…の…への)『適用』,応用《+『of』+『名』+『to』+『名』》 / 〈U〉〈C〉『申し込み』,志願;〈C〉願書 / 〈U〉(薬などを)塗ること,はること;〈C〉外用薬,化粧品 / 〈U〉(…に)心を傾けること,専心すること《+『to』+『名』》

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/02/05 21:01:16」(JST)

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UpToDate Contents

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English Journal

  • How do integrative practices influence patient-centered care?: An exploratory study comparing diabetes and mental health care.
  • Novikov Z1, Glover WJ, Trepman PC, Naveh E, Goldfracht M.
  • Health care management review.Health Care Manage Rev.2016 May 21. [Epub ahead of print]
  • BACKGROUND: Integration between organizational units to achieve common goals has been of interest to health systems because of the potential to improve patient-centered care. However, the means by which integrative practices actually influence patient-centered care remain unclear. Whereas many studi
  • PMID 26002414
  • Wrinkled, wavelength-tunable graphene-based surface topographies for directing cell alignment and morphology.
  • Wang Z1, Tonderys D2, Leggett SE3, Williams EK2, Kiani MT2, Steinberg RS4, Qiu Y4, Wong IY5, Hurt RH6.
  • Carbon.Carbon N Y.2016 Feb 1;97:14-24.
  • Textured surfaces with periodic topographical features and long-range order are highly attractive for directing cell-material interactions. They mimic physiological environments more accurately than planar surfaces and can fundamentally alter cell alignment, shape, gene expression, and cellular asse
  • PMID 25848137
  • Formation and Degradation of Beta-casomorphins in Dairy Processing.
  • Nguyen DD1, Johnson SK, Busetti F, Solah VA.
  • Critical reviews in food science and nutrition.Crit Rev Food Sci Nutr.2015 Dec 6;55(14):1955-67. doi: 10.1080/10408398.2012.740102.
  • Milk proteins including casein are sources of peptides with bioactivity. One of these peptides is beta-casomorphin (BCM) which belongs to a group of opioid peptides formed from β-casein variants. Beta-casomorphin 7 (BCM7) has been demonstrated to be enzymatically released from the A1 or B β-casein
  • PMID 25077377
  • Weighing the Evidence of Common Beliefs in Obesity Research.
  • Casazza K1, Brown A, Astrup A, Bertz F, Baum C, Brown MB, Dawson J, Durant N, Dutton G, Fields DA, Fontaine KR, Heymsfield S, Levitsky D, Mehta T, Menachemi N, Newby PK, Pate R, Raynor H, Rolls BJ, Sen B, Smith DL Jr, Thomas D, Wansink B, Allison DB.
  • Critical reviews in food science and nutrition.Crit Rev Food Sci Nutr.2015 Dec 6;55(14):2014-53. doi: 10.1080/10408398.2014.922044.
  • Obesity is a topic on which many views are strongly held in the absence of scientific evidence to support those views, and some views are strongly held despite evidence to contradict those views. We refer to the former as "presumptions" and the latter as "myths." Here, we present nine myths and 10 p
  • PMID 24950157

Japanese Journal

  • Aerosol Delivery of siRNA to the Lungs. Part 1: Rationale for Gene Delivery Systems
  • Youngren-Ortiz Susanne R.,Gandhi Nishant S.,España-Serrano Laura,Chougule Mahavir B.
  • KONA Powder and Particle Journal advpub(0), 2016
  • … The inhalation route of administration provides local delivery of siRNA therapeutics for the treatment of various pulmonary diseases, however barriers to pulmonary delivery and intracellular delivery of siRNA exists. …
  • NAID 130005102527
  • A novel in vivo corneal trans-epithelial electrical resistance measurement device
  • Uematsu Masafumi,Mohamed Yasser Helmy,Onizuka Naoko,Ueki Ryotaro,Inoue Daisuke,Fujikawa Azusa,Kitaoka Takashi
  • Journal of Pharmacological and Toxicological Methods 76, 65-71, 2015-11
  • … TER change after treatment with 0.02%BAC was similar to those determined by the established anterior chamber method. …
  • NAID 120005652775
  • Observation of carbon growth and interface structures in methanol solution
  • Okuno Kimio
  • Jpn. J. Appl. Phys. 54(11), 115502, 2015-10-05
  • … The reaction depth of the deposited carbon depends on the magnitude of electrolytic current and the treatment duration in the methanol solution. …
  • NAID 150000111438
  • 慢性血栓塞栓性肺高血圧症(CTEPH)におけるバルーン肺動脈形成術(BPA)手技の実際と治療成績 (第1土曜特集 肺高血圧症Update : 病態解明の進歩から治療への応用) -- (肺高血圧症治療update)

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リンク元100Cases 76」「care」「practice」「治療」「remedy
拡張検索posttreatment」「treatment failure

100Cases 76」


☆case76 頭痛
傾眠 drowsiness 正常病的の区別なく眠り込む場合に用いられる
意識不鮮明 confusion 周囲に対する認識や理解は低下し、思考清明さや記憶正確さが失われる
錯乱 confusion 夢幻様状態より見当識障害思考滅裂が見られる状態(PSY.40)
MA = Master of Arts 文学修士
 The Master of Arts (BrE: MA, UsE: M.A.) is awarded in Arts, Humanities, Theology and Social Sciences (Wikipedia)
graduate student 大学院生
rousable adj. 覚醒できる、目を覚ますことができる
rouse vt. ~の目を覚まさせる、呼び起こす。喚起する、鼓舞する、奮起させる。(感情を)起こさせる、かき立てる
lateralize vt. (生理)(大脳が)(左右半球に心的機能差がある、左右差がある。(器官機能活動などが)大脳の(左右いずれかの)片側優位下にある。(医学)(障害などが)大脳の片半球にあると診断される
乳頭浮腫 papilledema 原因を問わず視神経乳頭腫脹している状態
うっ血乳頭 choked disc 脳圧亢進による乳頭浮腫
24歳、男性 精神学の修士過程を専攻している大学院生
現病歴頭部全体に痛みがある。2回嘔吐傾眠錯乱が認められるようになった。明るい光を嫌う()he finds bright lights uncomfortable
既往歴病気既往はない。アレルギーはない。タバコ1日10本。アルコール24 unit/week(缶ビール(350ml)13.7本/週)。薬は服用してない。
診察 examination
 見た感じ紅潮しており、調子が悪そう。体温:39.2℃。項部硬直あり(he has stiffness on passice flexion of his neck)。皮疹なし。副鼻腔圧痛なし。鼓膜所見は正常脈拍:120/分。血圧:98/74 mmHg心血管系胸部腹部に異常所見なし(normal)。意識レベル低下。命令に応じて覚醒する(JCS10?)。局所神経症状認めない。眼底所見正常
検査 investigation
  髄液所見:混濁白血球:増多。蛋白:増多。糖:低下(普通の人の血糖100mg/dLと考える。→ 1g/L → 1/180 mol/L → 5.56 mmol/L。グラム染色結果待ち
・低血圧白血球増多、腎機能低下 → ウイルス性よりむしろ細菌性感染示唆する。 ← 重症敗血症敗血症ショックかな?(私見)
テーブル挿入 髄膜炎
・(疫学)HIM. 2621 (多分、全患者中(←私見))
 Streptococcus pneumoniae ~50%
 Neisseria meningitidis ~25%、
 group B streptococci ~15%
 Listeria monocytogenes ~10%
 Haemophilus influenzae type B <10%
Neisseria meningitidis全身性脈管皮疹(点状出血紫斑)が特徴的(generalized vasculitic rash)
 ・the most severe headaches are experienced in meningitis, subarachnoid hemorrhage and classic migraine.
  ・meningitis単回発作(single episode)。症状は時間単位で出現
  ・subarachnoid hemorrhage単回発作(single episode)。突然発症(突発完成?)。硝子体出血を認めることがある。
  ・classic migraine:繰り返す(数回/年~1回/週。平均月2回。発作は4-72時間継続)
髄膜刺激急性発熱をきたした多くの病態でみられる(acute febrile conditions)。特に子供。 ← そうなの?
頚部硬直頚部脊椎の局所感染症でも起こる。 ← パーキンソン病などによる筋トーヌスの異常亢進も除外しよう
・(細菌性)髄膜炎が疑われたら、確定診断する前に適切抗菌薬投与(empirical treatment)。 → 数時間の経過死亡することがある。
乳頭浮腫がない、あるいは占拠性病変示唆する片側性の神経徴候(lateralized neurological signs)がある患者では(CT結果を待たずに)腰椎穿刺をすぐにやるべき(CASES) ← どういう事?
局在性の神経徴候(localized neurological sign)がある場合はまずCTを撮るべき(CASES)。 → the dangers of coning ← 鉤ヘルニアの事?
 ・意識が低下しているのでそれなりの看護(must be nursed)。アヘン剤による鎮痛生理食塩水による低ナトリウム血症の補正。低血圧補正するためにinotrope(a drug with positive inotropic effects, e.g. dobutamine, digitalis, milrinone )も必要かもしれない。(100CASES)
 ・感受性のある抗菌薬投与(大量静注、髄液移行性の高いもの)、髄液所見の正常化・CRP 陰転後、1週間抗菌薬投与して治療終了対症療法として脳圧亢進には高張脳圧降下薬(マンニトールなど)を投与。(IMD.1042)
・(意訳)誰が3-4歳の世話をしていたのか分からないけど、子供検査すべき。髄膜炎菌か原因菌が不明だったら、リファンピシンによる予防的治療髄膜炎球菌に対する予防接種をすべき。 ← 日本ではどうなんでしょうか。
□350ml アルコール5%
350x0.05/10=1.75 unit
莢膜を有し、髄膜炎を起こす細菌 → 莢膜を有することで血液中補体などを介した貪食を免れ、血行性クモ膜下腔まで到達しうる。
Streptococcus pneumoniae
Haemophilus influenzae type b
Neisseria meningitidis
 感染症による全身性炎症反応症候群(SIRS)をセプシス(sepsis, 広義の敗血症?)とする
  1. 体温>38℃ or 体温<36℃
  2. 心拍数>90bpm
  3. 呼吸数>20回/min or PaCO2<32mmHg
  4. (白血球数>12,000/ul or 白血球数<4,000/ul) or ( 幼若好中球>10% ) ← ここでいう幼若好中球とは桿状好中球のことである。
 1. 全身性炎症反応症候群 systemic inflammatory response syndrome SIRS
 2. 敗血症 sepsis
 3. 重症敗血症 severe sepsis
 4. 敗血症ショック septic shock
 5. 多臓器機能障害症候群 multiorgan dysfunction syndrome MODS
 6. 多臓器不全 multiorgan failure MOF
HIM = Harrison's Principles of Internal Medicine 17th Edition
PSY = 標準精神医学 第3版
CASES = 100 Cases in Clinical Medicine Second edition
IMD = 内科診断学第2版



  • n.
  • 心配。心配事、煩労、心労、気苦労、気がかり、悩みのたね
  • 関心、配慮、注意。世話、保護、介護、ケア。関心事、責任、用事
care should be taken in combining a beta-blocker with a nondihydropyridine calcium channel blocker.
  • vi.
anxietyanxiousanxiouslyattendattendanceattentionattentionalcare forcaregivingcaringcautioncautiouslyconcerncurecuringfearheednervousnotenoticenursingnursing carepracticeprecautionremediationremedytherapeutictherapytreattreatmenttroubleuneasywatchworrisomeworry




  • n.
  • 実施、実行、実践、実際。経験。(数学)実算
  • (個人の)習慣。(社会の)慣行、慣例、習わし
  • (教会)礼拝式
  • 練習、実習、稽古
  • 熟練(skill)、手腕
  • (医師・弁護士などの)業務、営業。事務所、診療所
  • 患者、事件依頼人
  • vt.
  • vi.
carecarry outclinical practiceconductcurecuringcustomdoexecuteexecutionhabithabituationimplementimplementationmakemedical careperformperformanceprivate practiceremediationremedyruntherapeutictherapytreattreatmentundertake




therapymedical treatment treatmentcarepracticecurecuringremediationtreatcureremedytherapeutic



  • n.
  • 医療、治療、療法。治療薬
This includes abused substances such as alcohol, over-the-counter medications (such as high doses of acetaminophen), prescribed drugs with hepatotoxic side effects, and certain herbal remedies.
  • 救済策、矯正法(for, against)。(法)救済方法
  • (貨幣)公差
  • vi.
care, cure, curing, practice, regimen, remediation, therapeutic, therapeutic agent, therapeutic drug, therapy, treat, treatment




following therapy

treatment failure」