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GZR | |
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Geezer Butler in 2013 | |
| Background information | |
| Also known as | g//z/r, geezer |
| Origin | Houston, Texas, United States |
| Genres | Heavy metal, groove metal |
| Years active | 1995–2006 |
| Labels | TVT |
| Associated acts | Black Sabbath, Geezer Butler Band, Heaven & Hell, Fear Factory, Anacrusis, Cacophony, Social Distortion, Journey, Bad English, Ozzy Osbourne, Hardline, Killola, Lisa Rieffel, Symatic, Heaven's Flame, Crazy Angel, London Calling, Anger On Anger |
| Members | Geezer Butler Pedro Howse Chad Smith Clark Brown |
| Past members | Deen Castronovo Burton C. Bell Mario Frasca |
GZR was an American heavy metal band led by Black Sabbath bassist/lyricist Geezer Butler. The band has actually been marketed with three different names on their three releases. In 1995, the band was marketed as g//z/r. In 1997, it was merely geezer, and in 2005, it was GZR. Most fans refer to the band as Geezer, although Butler himself refers to the band name as "gee-zed-R."[citation needed] This incarnation of the band is not to be confused with Geezer's previous attempt in 1985 to form a solo band, then known as The Geezer Butler Band - the two bands are completely unrelated.
The band's name is derived from the name of its creator: Terence "Geezer" Butler.
Pedro Howse, the guitarist in the band, is Butler's nephew.
The music is generally of a much harder edge than Butler is known for in Black Sabbath. This is not a surprise, as the vocalist on his first album (Plastic Planet) was Burton C. Bell from Fear Factory, who is known for more driving and harder edged vocals than ever was displayed in Black Sabbath. Before taking on Bell as vocalist for Plastic Planet, Butler contacted Devin Townsend to perform on the album. However, due to Townsend's recent stint with Steve Vai and having had to sing lyrics not written by himself, he was unwilling to enter into another band where he would have no lyrical input. That album also featured Pedro Howse on guitars, as well as Deen Castronovo (of to come Journey fame) on drums. Bell did not stay with the band past the recording of Plastic Planet, due to Fear Factory commitments. In 1996, the band re-emerged with an exclusive track for the Mortal Kombat: More Kombat compilation, entitled 'Outworld' and featuring Anger On Anger vocalist, Mario Frasca.
This proved to be a one-time collaboration and Frasca was replaced by Clark Brown from the band Symatic for their second album Black Science, released in 1997. The g//z/r formation did play a few live dates in 1997 behind the release of the album, however this was not a full-fledged tour, most of these gigs were played concurrent to the Ozzfest tour of that year. The band opened for such folks as Bruce Dickinson, who was playing some live gigs at the time. Castronovo recorded, but did not play any of the live gigs. He was replaced on drums by Chad Smith (not to be confused with the Red Hot Chili Peppers drummer with the same name).
After the handful of live gigs in 1997, the band was mostly put on ice, as Geezer was busy with various things Black Sabbath related for quite a while. Geezer eventually got back into the studio with the same lineup that played the live gigs from 8 years previous, and recorded their third album, Ohmwork, which was released on May 9, 2005.
GZR | |
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| リンク元 | 「C型肝炎」「グラゾプレビル」 |
| 関連記事 | 「G」 |
| 一般名 | 略号 | 販売名 | 作用点 | |
| アスナプレビル | asunaprevir | ASV | スンベプラ | HCV NS3/4Aプロテアーゼ阻害 |
| エルバスビル | elbasvir | EBR | エレルサ | HCV NS5A阻害 |
| グラゾプレビル | grazoprevir | GZR | グラジナ | HCV NS3/4Aプロテアーゼ阻害 |
| グレカプレビル・ピブレンタスビル | glecaprevir/pibrentasvir | GLE/PIB | マヴィレット配合 | HCV NS3/4Aプロテアーゼ阻害・HCV NS5A阻害 |
| ソホスブビル | sofosbuvir | SOF | ソバルディ | 核酸アナログ |
| ソホスブビル・ベルパタスビル | sofosbuvir/velpatasvir | SOF/VEL | エプクルーサ配合 | 核酸アナログ |
| ダクラタスビル | daclatasvir | DCV | ダクルインザ | HCV NS5A複製複合体阻害 |
| リバビリン | ribavirin | RBV | レベトール、コペガス | 核酸アナログ |
| レジパスビル・ソホスブビル | sofosbuvir/ledipasvir | SOF/LDV | ハーボニー配合 | HCV NS5A阻害・核酸アナログ |
| C型肝炎ウイルスの遺伝子型 | DAA治療歴のない慢性肝炎 | ||
| 一般名 | 備考 | ||
| 1型 | SOF/LDV | sofosbuvir/ledipasvir | 腎障害では禁 |
| EBR+GZR | elbasvir+grazoprevir | ||
| GLE/PIB | glecaprevir/pibrentasvir | ||
| 2型 | SOF+RBV | sofosbuvir+ribavirin | 腎障害では禁 |
| GLE/PIB | glecaprevir/pibrentasvir | ||
| SOF/LDV | sofosbuvir/ledipasvir | 腎障害では禁 | |
| C型肝炎ウイルスの遺伝子型 | DAA治療歴のない代償性肝硬変 | ||
| 一般名 | 備考 | ||
| 1型 | SOF/LDV | sofosbuvir/ledipasvir | 腎障害では禁 |
| EBR+GZR | elbasvir+grazoprevir | ||
| GLE/PIB | glecaprevir/pibrentasvir | ||
| 2型 | SOF+RBV | sofosbuvir+ribavirin | 腎障害では禁 |
| GLE/PIB | glecaprevir/pibrentasvir | ||
| SOF/LDV | sofosbuvir/ledipasvir | 腎障害では禁 | |
| B型肝炎 | C型肝炎 | ソース | |
| 感染の特徴 | 慢性の肝細胞障害、 integrationによる変異誘発？ |
慢性の肝細胞障害 | 根拠なし |
| 劇症化 | 0.1-1％ | 0.1％ | HIM |
| 慢性化率 | 1-10％ | 85％ | HIM |
| キャリア化 | 稀。通常、母子感染でおこる | 医学辞書 | |
| 肝細胞癌患者中 | 約20％ | 約70％ | QB.B-281 |
| 肝細胞癌患者年齢 | 若年発症 | QB.B-281 | |
| 肝細胞癌発症形式 | 突発あり | 緩徐進展 | QB.B-281 |
| 遺伝子型 | B型肝炎ウイルス#遺伝子型 | ||
| A型、C型 | 1b型、2a型,、2b型 | ||
| 日本ではC型多く、重症化しやすいが、慢性化しにくい。しかし、インターフェロン奏効しにくく、肝細胞癌発症しやすい。 | 日本では1b型多い。インターフェロン奏効しづらい(15%)。平均は2型は奏効しやすい(80%以上でウイルス排除) | ||
| 治療 | インターフェロン ラミブジン アデフォビル エンテカビル テルビブジン |
ペグインターフェロン＋リバビリン |