網状層
WordNet
- dividing an area into zones or sections reserved for different purposes such as residence and business and manufacturing etc
PrepTutorEJDIC
- (都市計画の)区画制,地区制
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/10/01 23:50:42」(JST)
[Wiki en表示]
Zona reticularis |
Layers of cortex.
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Latin |
Zona reticularis |
Gray's |
p.1278 |
Anatomical terminology |
The zona reticularis is the innermost layer of the adrenal cortex, lying deep to the zona fasciculata and superficial to the adrenal medulla. The cells are arranged cords that project in different directions giving a net-like appearance (L. reticulum - net).[1]
Cells in the zona reticularis produce precursor androgens including dehydroepiandrosterone (DHEA) and androstenedione from cholesterol.[2] DHEA is further converted to DHEA-sulfate via a sulfotransferase, SULT2A1.[3] These precursors are not further converted in the adrenal cortex if the cells lack 17Beta Hydroxysteroid dehydrogenase. Instead, they are released into the blood stream and taken up in the testis and ovaries to produce testosterone and the estrogens respectively.
ACTH partially regulates adrenal androgen secretion,[4] also CRH.[5][6]
In humans the reticularis layer does contain 17 alpha-hydroxylase; this hydroxylates pregnenolone, which is then converted to cortisol by a mixed function oxidase. In rodents, the lack of 17alpha-hydroxylase results in the synthesis of corticosterone instead of cortisol as in the human.
adrenal gland (zona reticularis layer).
References
- ^ Histology: A Text and Atlas, 5th ed. Ross and Pawlina.
- ^ Wheater's Functional Histology, 5th ed. Young, Lowe, Stevens and Heath.
- ^ Rainey WE, Nakamura Y (February 2008). "Regulation of the Adrenal Androgen Biosynthesis". J. Steroid Biochem. Mol. Biol. 108 (3–5): 281–6. doi:10.1016/j.jsbmb.2007.09.015. PMC 2699571. PMID 17945481.
- ^ http://emedicine.medscape.com/article/919077-overview#showall
- ^ http://www.ncbi.nlm.nih.gov/pubmed/10473054
- ^ Principles and practice of geriatric surgery, By Ronnie A. Rosenthal, Michael E. Zenilman, Mark R. Katlic, page 302
External links
- Histology image: 14502loa - Histology Learning System at Boston University
- Anatomy Atlases - Microscopic Anatomy, plate 15.292 - "Adrenal Gland"
Human anatomy, endocrine system: endocrine glands (TA A11, TH H3.08, GA 11.1269)
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Islets of pancreas |
- Alpha cell
- Beta cell
- Delta cell
- PP cell
- Epsilon cell
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Hypothalamic/
pituitary axes
+parathyroid |
Pituitary |
Posterior pituitary |
- Pars nervosa
- Median eminence
- Infundibular stalk
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Anterior pituitary |
- Pars intermedia
- Pars tuberalis
- Pars distalis
- Acidophil cell
- Somatotropic cell
- Prolactin cell
- Basophil cell
- Corticotropic cell
- Gonadotropic cell
- Thyrotropic cell
- Chromophobe cell
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Thyroid axis |
Thyroid gland |
- Thyroid isthmus
- Lobes of thyroid gland
- Pyramidal lobe of thyroid gland
- Follicular cell
- Parafollicular cell
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Parathyroid gland |
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Adrenal axis:
Adrenal gland |
Cortex |
- Zona glomerulosa
- Zona fasciculata
- Zona reticularis
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Medulla |
- Medullary chromaffin cell
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Gonadal axis |
- Gonad: Testes
- Ovaries
- Corpus luteum
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Pineal gland |
- Pinealocyte
- Corpora arenacea
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Other |
- Enteroendocrine cell
- Paraganglion
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noco (d)/cong/tumr, sysi/epon
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proc, drug (A10/H1/H2/H3/H5)
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UpToDate Contents
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English Journal
- Fundamental studies of adrenal retinoid-X-receptor: Protein isoform, tissue expression, subcellular distribution, and ligand availability.
- Cheng B1, Al-Shammari FH2, Ghader IA2, Sequeira F2, Thakkar J2, Mathew TC3.
- The Journal of steroid biochemistry and molecular biology.J Steroid Biochem Mol Biol.2017 Mar 3. pii: S0960-0760(17)30067-5. doi: 10.1016/j.jsbmb.2017.03.002. [Epub ahead of print]
- PMID 28267642
- Glucocorticoid-deficient hypoadrenocorticism secondary to intravascular lymphoma in the adrenal glands of a dog.
- Buckley ME1, Chapman PS1, Walsh A2.
- Australian veterinary journal.Aust Vet J.2017 Mar;95(3):64-67. doi: 10.1111/avj.12539.
- PMID 28239861
- Regulation of aldosterone secretion by mineralocorticoid receptor-mediated signaling.
- Chong C1, Hamid A1, Yao T1, Garza AE1, Pojoga LH1, Adler GK1, Romero JR1, Williams GH2.
- The Journal of endocrinology.J Endocrinol.2017 Mar;232(3):525-534. doi: 10.1530/JOE-16-0452. Epub 2017 Jan 17.
- PMID 28096435
Japanese Journal
- Functional zonation of the rat adrenal cortex: the development and maintenance
- A Morphometric Study of the Adrenal Cortex of the Female DDD Mouse(Anatomy)
- The journal of veterinary medical science 71(2), 183-187, 2009-02-25
- NAID 110007109595
- Analysis of mRNA expression for steroidogenic enzymes in the remaining adrenal cortices attached to adrenocortical adenomas.
Related Links
- the innermost part of the adrenal cortex, which borders on the adrenal medulla part of the gland. It acts in consort with the zona fasciculata in producing ... 14]C]DDE binding was confined to zona fasciculata, while zona glomerulosa, zona reticularis ...
- The adrenal glands are paired endocrine glands found on top of the kidneys. They are composed of an inner medulla and an outer cortex, which is in turn divided into three zones. The zona reticularis is the innermost layer of the ...
Related Pictures
★リンクテーブル★
[★]
- 英
- adrenocortical hormone
- 同
- 副腎皮質ステロイド adrenocorticoids
- 関
- 副腎皮質刺激ホルモン放出ホルモン、副腎皮質刺激ホルモン
- ステロイド
- 関
- 副腎、副腎皮質、ステロイド、コルチコステロイド、ステロイドホルモン、コルチコイド。副腎皮質ホルモン剤
種類(主要なもののみ)
- 球状層から分泌される。アルドステロン
- 索状層から分泌される。コルチゾール
- 網状層から分泌される。アンドロステンジオン
臨床関連
- 21-hydroxylaseが正常に機能しないことにより生じる (L.320)
薬理学
副腎皮質から分泌されるホルモン (SP.895)
[★]
- 英
- adrenal gland (KH), suprarenal gland (Z)
- 同
- 腎上体
解剖
血管(図:N.322)
- ref(renal_gland_av.png,副腎)
組織
機能
[★]
- 英
- adrenal cortex (Z)
- 関
- 副腎
- ATCHは副腎皮質の索状層、網状層に作用して、それぞれの層で糖質コルチコイドと副腎アンドロジェンの産生を促す(2007年後期生理学授業プリント)
構造
ホルモン
まとめ
[★]
- 英
- zona reticularis
- 同
- 網状帯
- 関
- 副腎皮質、球状層、束状層
- 作用は弱く正常状態ではほとんど無視できる (HIS.272)
- 不規則に並んだ細胞索からなり、皮質の7%をしめる。好酸性の細胞質はやあヤンチョウであるが、多数のリポフスチン顆粒の存在による (HIS.272)
[★]
網状層、網状帯
- 関
- reticular layer、stratum lacunosum、stratum reticulare、zona reticularis
[★]
- 関
- band、cingulum、herpes zoster、shingles、zonae、zone、zoster
[★]
網状の
- 関
- plexiform、reticular、reticulate