WordNet

prevent completion; "stop the project"; "break off the negotiations" (同)break off, discontinue, stop
happen; "Report the news as it develops"; "These political movements recrudesce from time to time" (同)recrudesce, develop
become separated into pieces or fragments; "The figurine broke"; "The freshly baked loaf fell apart" (同)separate, split up, fall_apart, come apart
be broken in; "If the new teacher wont break, well add some stress"
crack; of the male voice in puberty; "his voice is breaking--he should no longer sing in the choir"
destroy the integrity of; usually by force; cause to separate into pieces or fragments; "He broke the glass plate"; "She broke the match"
diminish or discontinue abruptly; "The patients fever broke last night"
fall sharply; "stock prices broke"
render inoperable or ineffective; "You broke the alarm clock when you took it apart!"
weaken or destroy in spirit or body; "His resistance was broken"; "a man broken by the terrible experience of near-death"
vary or interrupt a uniformity or continuity; "The flat plain was broken by tall mesas"
(tennis) a score consisting of winning a game when your opponent was serving; "he was up two breaks in the second set" (同)break of serve
an escape from jail; "the breakout was carefully planned" (同)breakout, jailbreak, gaolbreak, prisonbreak, prison-breaking
an act of delaying or interrupting the continuity; "it was presented without commercial breaks"; "there was a gap in his account" (同)interruption, disruption, gap
a sudden dash; "he made a break for the open door"
the opening shot that scatters the balls in billiards or pool
an unexpected piece of good luck; "he finally got his big break" (同)good_luck, happy chance
an abrupt change in the tone or register of the voice (as at puberty or due to emotion); "then there was a break in her voice"
the occurrence of breaking; "the break in the dam threatened the valley"
interrupt a continued activity; "She had broken with the traditional patterns" (同)break away
break a piece from a whole; "break a branch from a tree" (同)break off, snap off
move away or escape suddenly; "The horses broke from the stable"; "Three inmates broke jail"; "Nobody can break out--this prison is high security" (同)break_out, break away
destroy the completeness of a set of related items; "The book dealer would not break the set" (同)break_up
force out or release suddenly and often violently something pent up; "break into tears"; "erupt in anger" (同)burst, erupt
ruin completely; "He busted my radio!" (同)bust
be released or become known; of news; "News of her death broke in the morning" (同)get_out, get_around
go to pieces; "The lawn mower finally broke"; "The gears wore out"; "The old chair finally fell apart completely" (同)wear, wear_out, bust, fall_apart
become punctured or penetrated; "The skin broke"
cause the failure or ruin of; "His peccadilloes finally broke his marriage"; "This play will either make or break the playwright"
cause to give up a habit; "She finally broke herself of smoking cigarettes"
change directions suddenly
change suddenly from one tone quality or register to another; "Her voice broke to a whisper when she started to talk about her children"
come forth or begin from a state of latency; "The first winter storm broke over New York"
come into being; "light broke over the horizon"; "Voices broke in the air"
come to an end; "The heat wave finally broke yesterday"
curl over and fall apart in surf or foam, of waves; "The surf broke"
emerge from the surface of a body of water; "The whales broke"
exchange for smaller units of money; "I had to break a $100 bill just to buy the candy"
find a flaw in; "break an alibi"; "break down a proof"
find the solution or key to; "break the code"
give up; "break cigarette smoking"
happen or take place; "Things have been breaking pretty well for us in the past few months"
interrupt the flow of current in; "break a circuit"
invalidate by judicial action; "The will was broken"
make a rupture in the ranks of the enemy or ones own by quitting or fleeing; "The ranks broke"
make the opening shot that scatters the balls
pierce or penetrate; "The blade broke her skin"
scatter or part; "The clouds broke after the heavy downpour"
separate from a clinch, in boxing; "The referee broke the boxers"
undergo breaking; "The simple vowels broke in many Germanic languages"
a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; "humans have 22 chromosome pairs plus two sex chromosomes"

PrepTutorEJDIC

…'を'『壊す』,割る,砕く;…'を'折る / …'を'擦りむく / …'を'『役に立たなくする』,壊す / (小さな物に)〈組になった物〉'を'分ける,ばらす,〈お金〉'を'くずす《+『名』+『into』+『名』》 / 〈垣・へいなど〉'を'破って出る / 〈法律・規則・約束など〉'を'『破る』,犯す / 〈均整・秩序・配列など〉'を'破る,くずす;〈持続しているもの〉'を'中止する,妨げる / 〈記録〉'を'破る,更新する / (…に)…'を'打ち明ける,知らせる《+『名』+『to』+『名』》 / …'を'破産させる,倒産させる / 〈気力・抵抗など〉'を'くじく;〈力・効果・強度〉'を'弱める / (…に)…‘の'位を下げる,…'を'降等させる《+『名』+『to』+『名』》 / 〈動物〉'を'ならす / 〈人〉‘の'(…の)癖を直す《+『名』〈人〉+『of』+『名』(do『ing』)》 / 〈暗号など〉'を'解読する;〈事件・問題など〉を解決する,解く / 《しばしば副詞[句]を伴って》『壊れる』,砕ける,割れる;破れる,破裂する / ぷっつりと切れる;中断する,途切れる;《米》仕事を中断する / はずれる,離れる,分離する《+『off』(『away』)》 / 故障する,壊れる,動かなくなる / 突然始まる;突然変化する / 夜が明ける / 〈健康・気力などが〉衰える,弱る;〈心が〉悲しみに打ちひしがれる / 〈株・価格などが〉急落する,暴落する / 壊れた箇所,裂け目,割れ目 / 中断,途切れ;不和,仲たがい / 休憩時間,小休止 / 逃亡計画,脱獄 / (…に向かっての)突進 / 急な変化,顕著な変化 / 夜明け / 《話》運,機会
染色体

UpToDate Contents

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1. 染色体の転座、欠失、および逆位 chromosomal translocations deletions and inversions
2. 急性骨髄性白血病における細胞遺伝学 cytogenetics in acute myeloid leukemia
3. 先天性の細胞遺伝学的異常 congenital cytogenetic abnormalities
4. 遺伝性疾患の基本原則 basic principles of genetic disease
5. 小細胞肺癌の病理および病期分類 pathobiology and staging of small cell carcinoma of the lung

English Journal

Genotoxicity assessment of pulp and paper mill effluent before and after bacterial degradation using Allium cepa test.

Haq I1, Kumar S2, Raj A3, Lohani M4, Satyanarayana GN5.
Chemosphere.Chemosphere.2017 Feb;169:642-650. doi: 10.1016/j.chemosphere.2016.11.101. Epub 2016 Nov 29.
A lignin peroxidases-producing Serratia liquefaciens was used for bioremediation of pulp and paper (P&P) mill effluent. The treatment led to reduction of chemical oxygen demand (COD), colour, lignin and phenolic content by 84%, 72%, 61% and 95%, respectively. The effluent detoxification was stud
PMID 27912189

No influence of BCR-ABL1 transcript types e13a2 and e14a2 on long-term survival: results in 1494 patients with chronic myeloid leukemia treated with imatinib.

Pfirrmann M1, Evtimova D2, Saussele S3, Castagnetti F4, Cervantes F5, Janssen J6, Hoffmann VS2, Gugliotta G4, Hehlmann R3, Hochhaus A7, Hasford J2, Baccarani M4.
Journal of cancer research and clinical oncology.J Cancer Res Clin Oncol.2017 Jan 12. doi: 10.1007/s00432-016-2321-2. [Epub ahead of print]
PURPOSE: The genomic break on the major breakpoint cluster region of chromosome 22 results in two BCR-ABL1 transcripts of different sizes, e14a2 and e13a2. Favorable survival probabilities of patients with chronic myeloid leukemia (CML) in combination with too small patient samples may yet have obst
PMID 28083711

Regulating chromosomal movement by the cochaperone FKB-6 ensures timely pairing and synapsis.

Alleva B1, Balukoff N1, Peiper A1, Smolikove S2.
The Journal of cell biology.J Cell Biol.2017 Jan 11. pii: jcb.201606126. doi: 10.1083/jcb.201606126. [Epub ahead of print]
In meiotic prophase I, homologous chromosome pairing is promoted through chromosome movement mediated by nuclear envelope proteins, microtubules, and dynein. After proper homologue pairing has been established, the synaptonemal complex (SC) assembles along the paired homologues, stabilizing their in
PMID 28077446

Japanese Journal

Protein phosphatase 4 promotes chromosome pairing and synapsis, and contributes to maintaining crossover competence with increasing age.

Sato-Carlton Aya,Li Xuan,Crawley Oliver,Testori Sarah,Martinez-Perez Enrique,Sugimoto Asako,Carlton Peter M
PLoS genetics 10(10), 2014-10-23
… Prior to the meiotic divisions, dynamic chromosome reorganizations including pairing, synapsis, and recombination of maternal and paternal chromosome pairs must occur in a highly regulated fashion during meiotic prophase. …
NAID 120005515540

電離放射線と血液がん

坂井晃
臨床血液 55(10), 2046-2053, 2014
NAID 130004696098

高齢者に発症しinv(2)(p23q35)を認めたALK陽性未分化大細胞型リンパ腫の1例

岡森慧,前迫善智,江原淳,藤田久美,竹岡加陽,林田雅彦,奥村敦子,大野仁嗣
天理医学紀要 16(2), 89-100, 2013
… GバンディングとALK break-apart probe を用いたFISHで, 核型は42~46,XY,+2,inv(2)(p23q35), der(2)inv(2)(p23q35)del(2)(p21), 13,der(16)t(1;16)(q12;p13),18,+mar[cp11]. …
NAID 130004676058