WordNet
- reimbursement for goods damaged while in transit or in use
- the quantity broken; "the total breakage was huge"
- the act of breaking something; "the breakage was unavoidable" (同)break, breaking
- a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; "humans have 22 chromosome pairs plus two sex chromosomes"
PrepTutorEJDIC
- 〈U〉破損;〈C〉破損箇所 / 破損量 / 〈C〉《通例複数形で》《英》破損物 / 〈C〉破損額
- 染色体
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- 1. 小児および思春期における遺伝性再生不良性貧血 inherited aplastic anemia in children and adolescents
- 2. 染色体の転座、欠失、および逆位 chromosomal translocations deletions and inversions
- 3. 先天異常の遺伝学的および環境的原因 genetic and environmental causes of birth defects
- 4. ナイミーヘン染色体不安定症候群 nijmegen breakage syndrome
- 5. ブルーム症候群 bloom syndrome
English Journal
- TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.
- Gómez-Herreros F1, Schuurs-Hoeijmakers JH2, McCormack M3, Greally MT4, Rulten S5, Romero-Granados R6, Counihan TJ7, Chaila E8, Conroy J9, Ennis S9, Delanty N10, Cortés-Ledesma F6, de Brouwer AP11, Cavalleri GL12, El-Khamisy SF13, de Vries BB11, Caldecott KW5.
- Nature genetics.Nat Genet.2014 May;46(5):516-21. doi: 10.1038/ng.2929. Epub 2014 Mar 23.
- Topoisomerase II (TOP2) removes torsional stress from DNA and facilitates gene transcription by introducing transient DNA double-strand breaks (DSBs). Such DSBs are normally rejoined by TOP2 but on occasion can become abortive and remain unsealed. Here we identify homozygous mutations in the TDP2 ge
- PMID 24658003
- Protein ADP-ribosylation and the cellular response to DNA strand breaks.
- Caldecott KW.
- DNA repair.DNA Repair (Amst).2014 Apr 20. pii: S1568-7864(14)00092-5. doi: 10.1016/j.dnarep.2014.03.021. [Epub ahead of print]
- DNA strand breaks arise continuously in cells and can lead to chromosome rearrangements and genome instability or cell death. The commonest DNA breaks are DNA single-strand breaks, which arise at a frequency of tens-of-thousands per cell each day and which can block the progression of RNA/DNA polyme
- PMID 24755000
- Chromosome Breakage Induced by the Genotoxic Agents Mitomycin C and Cytosine arabinoside is Concentration and p53 Dependent.
- Brüsehafer K1, Rees BJ, Manshian BB, Doherty AT, O'Donovan MR, Doak SH, Scott Jenkins GJ.
- Toxicological sciences : an official journal of the Society of Toxicology.Toxicol Sci.2014 Apr 19. [Epub ahead of print]
- The p53 tumor suppressor protein plays an essential role in cellular integrity and inactivation of the TP53 gene by mutation is the most frequent alteration in human cancer. As loss of p53 function is associated with increased genetic instability, it is important in genotoxicity testing to explore t
- PMID 24675086
Japanese Journal
- Role of NBS1 in DNA damage response and its relationship with cancer development
- Saito Yuichiro,Fujimoto Hiroko,Kobayashi Junya
- Translational Cancer Research 2(3), 178-189, 2013-06
- … Nijmegen breakage syndrome (NBS) is a recessive genetic disorder characterized by an elevated sensitivity to ionizing radiation, chromosome instability, and a high frequency of malignancies phenotypes similar to those of ataxia-telangiectasia (A-T). …
- NAID 120005300469
- Dissection of rye chromosomes by the gametocidal system
- Li Jianjian,Nasuda Shuhei,Endo Takashi R.
- Genes & Genetic Systems 88(6), 321-327, 2013
- … Chromosome mutations occur in common wheat carrying a monosome of gametocidal (Gc) chromosomes 2C and 3CSAT. … These Gc chromosomes have been known to induce chromosomal breakage in a rye chromosome 1R added to common wheat. … We attempted to introduce the two Gc chromosomes into the other six rye chromosome (2R to 7R) addition or substitution lines of common wheat to establish a set of chromosomal rearrangement-inducing lines for rye chromosomes. …
- NAID 130004137816
- Infertility Associated with Meiotic Failure in the tremor Rat (tm/tm) is Caused by the Deletion of Spermatogenesis Associated 22
- ISHISHITA Satoshi,INUI Toshihide,MATSUDA Youichi [他],Serikawa Tadao,Kitada Kazuhiro
- Experimental Animals 62(3), 219-227, 2013
- … Spermatogenesis associated 22 (Spata22) has been shown to be a vertebrate-specific gene essential for the progression of meiosis through prophase I and completion of chromosome synapsis and meiotic recombination using a mouse repro42 mutant carrying an N-ethyl-N-nitrosourea (ENU)-induced nonsense mutation in Spata22. … Precise mapping of the breakage point revealed that the deleted genomic region spanned approximately 240 kb and comprised at least 13 genes, including Spata22. …
- NAID 130003362962
Related Links
- Syndrome Gene Symbol: Chromosome Band Hypersensitivity: Immunodeficiencies Chromosome Breakage Cancer Risk Ataxia telangiectasia ATM: 11q22.3 (11q22–11q23 Human Genome Organization) ...
- Chromosome Breakage: A type of chromosomal aberration involving DNA BREAKS. Chromosome breakage can result in CHROMOSOMAL TRANSLOCATION; CHROMOSOME INVERSION; or SEQUENCE DELETION. ... 01/01 ...
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★リンクテーブル★
| リンク元 | 「染色体切断」「chromosome break」「chromosomal break」「chromosomal breakage」 |
| 関連記事 | 「breakage」 |
「染色体切断」
「chromosome break」
「chromosomal break」
「chromosomal breakage」
「breakage」
- n.
- 関
- ablate、ablation、amputate、amputation、break、cleavage、cleave、damage、disruption、scission、sever、transection、truncate、truncation