WordNet

used of hair or haircuts; "a close military haircut"
finish a game in baseball by protecting a lead; "The relief pitcher closed with two runs in the second inning"
inclined to secrecy or reticence about divulging information; "although they knew her whereabouts her friends kept close about it" (同)closelipped, closemouthed, secretive, tightlipped
in an attentive manner; "he remained close on his guard" (同)closely, tight
come together, as if in an embrace; "Her arms closed around her long lost relative" (同)come_together
crowded; "close quarters" (同)confining
marked by fidelity to an original; "a close translation"; "a faithful copy of the portrait"; "a faithful rendering of the observed facts" (同)faithful
fill or stop up; "Can you close the cracks with caulking?" (同)fill_up
become closed; "The windows closed with a loud bang" (同)shut
move so that an opening or passage is obstructed; make shut; "Close the door"; "shut the window" (同)shut
fitting closely but comfortably; "a close fit" (同)snug, close-fitting
(of a contest or contestants) evenly matched; "a close contest"; "a close election"; "a tight game" (同)tight
of textiles; "a close weave"; "smooth percale with a very tight weave" (同)tight
at or within a short distance in space or time or having elements near each other; "close to noon"; "how close are we to town?"; "a close formation of ships"
bar access to; "Due to the accident, the road had to be closed for several hours"
be priced or listed when trading stops; "The stock market closed high this Friday"; "My new stocks closed at $59 last night"
bring together all the elements or parts of; "Management closed ranks"
cause a window or an application to disappear on a computer desktop
change ones body stance so that the forward shoulder and foot are closer to the intended point of impact
close in relevance or relationship; "a close family"; "we are all...in close sympathy with..."; "close kin"; "a close resemblance"
complete a business deal, negotiation, or an agreement; "We closed on the house on Friday"; "They closed the deal on the building"
confined to specific persons; "a close secret"
draw near; "The probe closed with the space station"
engage at close quarters; "close with the enemy"
finish or terminate (meetings, speeches, etc.); "The meeting was closed with a charge by the chairman of the board"
rigorously attentive; strict and thorough; "close supervision"; "paid close attention"; "a close study"; "kept a close watch on expenditures"
strictly confined or guarded; "kept under close custody"
with shutters closed
blocked against entry; "a closed porch" (同)closed in
used especially of mouth or eyes; "he sat quietly with closed eyes"; "his eyes were shut against the sunlight" (同)shut
not having an open mind; "a closed mind unreceptive to new ideas" (同)unsympathetic
(set theory) of an interval that contains both its endpoints
not open or affording passage or access; "the many closed streets made travel difficult"; "our neighbors peeped from behind closed curtains"
not open to the general public; "a closed meeting"
requiring union membership; "a closed shop"
describing a circle; moving in a circle; "the circular motion of the wheel" (同)rotary, orbitual
an advertisement (usually printed on a page or in a leaflet) intended for wide distribution; "he mailed the circular to all subscribers" (同)handbill, bill, broadside, broadsheet, flier, flyer, throwaway
the 4th letter of the Roman alphabet (同)d
of or relating to or characterized by covalence; "covalent bond"

PrepTutorEJDIC

…'を'『閉じる』,閉める(shut) / …'を'ふさぐ(fill) / 〈事務・仕事・話など〉'を'『終える』,済ませる / 〈通路・施設など〉'を'一時的に閉じる,‘の'使用を一時中止する / (一つにまとまるように)…'を'つめる / 〈ドア・目・花などが〉『閉じる』,閉まる;ふさがる / 〈話・相談・契約などが〉『終る』,終了する,〈店などが〉終業(休業)する / くっつく,接近する(come together) / 終結,結末,終り(end) / 締め切り / (音楽の)終止
(距離・時間・関係が)『近い』,接近している・《名詞の前にのみ用いて》『親密な』,親しい・ぎっしり詰まった,密集した;目のつんだ,きめの細かい・綿密な,厳重な(strict) ・息がつまる,重苦しい(stuffy) / 厳重に隠された,秘密の / ほとんど同等の,匹敵する・《補語にのみ用いて》(金銭が)乏しい;(…に)けちな(stingy)《+『with』+『名』》・(音声が)閉鎖音の(舌を口蓋(こうがい)に近づけて発音する) / (…に)『近接して』,(…の)すぐそば(近く)に;(…に)ぴったりくっついて《+『to(behind, by)』+『名』》 / きっちりと;ぎっしりと・(大寺院の)囲い地;(学校の)構内,校庭・《英》袋小路
『円形の』,丸い / 回転して動く / 循環的な,旋回する;回遊する / (公衆に配布する)案内状,広告ビラ
deuteriumの化学記号

UpToDate Contents

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1. B型肝炎ウイルス感染の診断 diagnosis of hepatitis b virus infection
2. 慢性B型肝炎ウイルスに感染したHIV感染患者のモニタリング monitoring the hiv infected patient with chronic hepatitis b virus infection
3. B型肝炎ウイルスの特性および感染の病因 characteristics of the hepatitis b virus and pathogenesis of infection
4. 慢性B型肝炎ウイルス感染に対する従来型インターフェロンおよびペグインターフェロン standard and pegylated interferon for chronic hepatitis b virus infection
5. DNA父子鑑定検査 paternity testing using dna

English Journal

Japanese Journal

An interferon-like small chemical compound CDM-3008 suppresses hepatitis B virus through induction of interferon-stimulated genes

Furutani Yutaka,Toguchi Mariko,Shiozaki-Sato Yumi,Qin Xian-Yang,Ebisui Etsuko,Higuchi Shoko,Sudoh Masayuki,Suzuki Harukazu,Takahashi Nobuaki,Watashi Koichi,Wakita Takaji,Kakeya Hideaki,Kojima Soichi
PLOS ONE 14(6), 2019-06-12
B型肝炎ウイルス抑制物質の作用機序解明 --新規抗B型肝炎治療薬の開発へ期待--. 京都大学プレスリリース. 2019-06-13.
NAID 120006644069

Screening for inhibitor of episomal DNA identified dicumarol as a hepatitis B virus inhibitor

Takeuchi Fumihiko,Ikeda Sotaro,Tsukamoto Yuta,Iwasawa Yoshikazu,Chen Qihao,Otakaki Yukie,Ouda Ryota,Yao Wan-Ling,Narita Ryo,Hijikata Makoto,Watashi Koichi,Wakita Takaji,Takeuchi Koh,Chayama Kazuaki,Kogure Amane,Kato Hiroki,Fujita Takashi
PLOS ONE 14(2), 2019-02-19
… This is due to the difficulty in eliminating viral covalently closed circular (ccc) DNA, which is central to the gene expression and replication of HBV. … We developed an assay system for nuclear circular DNA using an integration-deficient lentiviral vector. … This vector produced non-integrated circular DNA in nuclei of infected cells. …
NAID 120006822498

B型肝炎ウイルスの組換え閉環状DNAはモデルマウスで慢性肝炎を伴う長期のウイルス持続感染を誘発

Li Gaiyun,Zhu Yuanfei,Shao Dianhui,Chang Hao,Zhang Xiaoming,Zhou Dongming,Gao Yueqiu,Lan Ke,Deng Qiang
Hepatology : official journal of the American Association for the Study of Liver Diseases 13(2), 2-15, 2018-08
NAID 40021677987