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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/11/10 21:59:55」(JST)

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English Journal

  • Therapeutic potential of VEGF and VEGF-derived peptide in peripheral neuropathies.
  • Verheyen A, Peeraer E, Lambrechts D, Poesen K, Carmeliet P, Shibuya M, Pintelon I, Timmermans JP, Nuydens R, Meert T.SourceDepartment of Neuroscience, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, B-2340 Beerse, Belgium.
  • Neuroscience.Neuroscience.2013 Aug 6;244:77-89. doi: 10.1016/j.neuroscience.2013.03.050. Epub 2013 Apr 11.
  • Besides its prominent role in angiogenesis, the vascular endothelial growth factor (VEGF) also exerts important protective effects on neurons. In particular, mice expressing reduced levels of VEGF suffer from late-onset motor neuron degeneration, whereas VEGF delivery significantly delays motor neur
  • PMID 23583762
  • Developments in the systemic treatment of metastatic cervical cancer.
  • Mountzios G, Soultati A, Pectasides D, Pectasides E, Dimopoulos MA, Papadimitriou CA.SourceDepartment of Medical Oncology and Translational Research, 251 Airforce General Hospital, Athens, Greece; Department of Clinical Therapeutics, University of Athens School of Medicine, "Alexandra" University Hospital, Athens, Greece. Electronic address:
  • Cancer treatment reviews.Cancer Treat Rev.2013 Aug;39(5):430-43. doi: 10.1016/j.ctrv.2012.05.009. Epub 2012 Jun 22.
  • Despite the available prevention and early detection strategies, advanced squamous-cell carcinoma of the uterine cervix remains a major concern for public health. Systemic treatment with cisplatin, either in combination with external beam irradiation for locally advanced disease, or as monotherapy f
  • PMID 22727690

Japanese Journal

  • カルボプラチン,パクリタキセル製剤のジェネリック品変更前後における有害事象の検討
  • 古市 基彦,村松 高,四万村 三惠 [他]
  • 日大医学雑誌 = Journal of Nihon University Medical Association 71(6), 424-427, 2012-12-00
  • NAID 40019547217
  • 進行性精巣腫瘍に対するSalvage化学療法 (第61回日本泌尿器科学会中部総会 シンポジウム9「精巣腫瘍診療ガイドラインを検証する」)
  • 中村 晃和,三木 恒治
  • 泌尿器科紀要 = Acta urologica Japonica 58(12), 721-725, 2012-12-00
  • … Therefore, new drugs such as paclitaxel, gemcitabine and irinotecan have been used as salvage chemotherapy. … Especially, TIP (paclitaxel, ifosfamide, cisplatin) therapy has become a new treatment option as first salvage chemotherapy in patients with favorable features such as testis primary and first relapse after complete remission. … Regarding gemcitabine or irinotecan, some regimens have been reported in combination with oxaliplatin or paclitaxel. …
  • NAID 40019530849

Related Links

Antineoplastic drug administered intraveneously for several cancer types. ... Paclitaxel is an anti-cancer drug, also known as Taxol and Onxol. The drug is first line treatment for ovarian, breast, lung, and colon cancer and ...

Related Pictures of Paclitaxel structurePaclitaxel (Taxol), Best quality, Large T2003 paclitaxelPaclitaxel | Brand names include Onxol Web information on Paclitaxel

拡張検索paclitaxel poliglumex



タキソール taxol TXL、(アルブミン添加)アブラキサン


  • 抗悪性腫瘍薬
  • タキサン系


  • 卵巣癌、非小細胞肺癌、乳癌、胃癌、子宮体癌、再発又は遠隔転移を有する頭頸部癌、再発又は遠隔転移を有する食道癌、血管肉腫、進行又は再発の子宮頸癌


  • チューブリンの脱重合を抑制して、中間径フィラメントを安定化させることで有糸分裂期(M期)を停止させ、これにより細胞分裂を阻害 (⇔ ビンクリスチン)


  • 骨髄抑制。過敏反応。低血圧、高血圧、徐脈。関節痛(高頻度)、筋肉痛(高頻度)。発熱(高頻度)。末梢神経障害(高頻度)。感染症、出血傾向。




antineoplastic drug, antitumor agent, antitumor drug
抗腫瘍薬 antineoplastics、抗癌薬 anticancer drug AZT


first aid step1 2006 p.307,308



paclitaxel poliglumex」