delayed type allergic reaction

IV型アレルギー

WordNet

1. write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
2. a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
3. (biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
5. all of the tokens of the same symbol; "the word `element contains five different types of character"
6. printed characters; "small type is hard to read"
7. identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
8. (mechanics) the equal and opposite force that is produced when any force is applied to a body; "every action has an equal and opposite reaction"
9. a response that reveals a persons feelings or attitude; "he was pleased by the audiences reaction to his performance"; "John feared his mothers reaction when she saw the broken lamp"
10. a bodily process occurring due to the effect of some antecedent stimulus or agent; "a bad reaction to the medicine"; "his responses have slowed with age" (同)response
11. doing something in opposition to another way of doing it that you dont like; "his style of painting was a reaction against cubism"
12. an idea evoked by some experience; "his reaction to the news was to start planning what to do"
13. extreme conservatism in political or social matters; "the forces of reaction carried the election"
14. act later than planned, scheduled, or required; "Dont delay your application to graduate school or else it wont be considered"
15. time during which some action is awaited; "instant replay caused too long a delay"; "he ordered a hold in the action" (同)hold, time_lag, postponement, wait
16. the act of delaying; inactivity resulting in something being put off until a later time (同)holdup
17. cause to be slowed down or delayed; "Traffic was delayed by the bad weather"; "she delayed the work that she didnt want to perform" (同)detain, hold_up
18. characterized by or caused by allergy; "an allergic reaction"
19. having an allergy or peculiar or excessive susceptibility (especially to a specific factor); "allergic children"; "hypersensitive to pollen" (同)hypersensitive, hypersensitized, hypersensitised, sensitized, sensitised, supersensitive, supersensitized, supersensitised
20. not as far along as normal in development

PrepTutorEJDIC

1. 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
2. {名}(…に対する)『反応』《+『to』+『名』》 / 〈U〉(…に対する)(政治的・社会的な)『反動』,逆コース《+『against』+『名』》 / 〈U〉〈C〉化学反応,化学変化 / 〈U〉〈C〉(物理学で)反作用
3. …'を'『延期する』,延ばす / 〈事故などが〉…'を'『遅らせる』 / 『ぐずぐずする』,『手間取る』 / 『遅れ』,遅延 / 『延期』,猶予
4. アレルギー性の;(…に)アレルギーを起こす《+『to』+『名』》 / 《補語にのみ用いて》《話》(…に)神経過敏の,(…が)大きらいの《+『to』+『名』(do『ing)』》

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 薬物アレルギー患者へのアプローチ an approach to the patient with drug allergy
• 2. 薬物アレルギー：分類および臨床的特徴 drug allergy classification and clinical features
• 3. 神経線維腫症I型（NF1）：病因、臨床的特徴、および診断 neurofibromatosis type 1 nf1 pathogenesis clinical features and diagnosis
• 4. 予防接種に対するアレルギー反応 allergic reactions to vaccines
• 5. 局所麻酔剤に対するアレルギー反応 allergic reactions to local anesthetics

English Journal

• Oxyresveratrol ameliorates allergic airway inflammation via attenuation of IL-4, IL-5, and IL-13 expression levels.

• Ashraf MI1, Shahzad M2, Shabbir A1.
• Cytokine.Cytokine.2015 Dec;76(2):375-81. doi: 10.1016/j.cyto.2015.09.013. Epub 2015 Oct 1.
• AIM: Oxyresveratrol is known to possess anti-inflammatory property. Current study investigates the immunosuppressive effect of oxyresveratrol by using mouse model of ovalbumin (OVA)-induced allergic airway inflammation.METHODS: BALB/c mice were randomly divided into five groups having 8 mice in each
• PMID 26431781

• Immunomodulatory activity of methanol leaf extracts of Cameroonian medicinal plants.

• Djafoua YM, Mouokeu RS, Tume C, Kamtchueng MO, Kuiate JR.
• Journal of complementary & integrative medicine.J Complement Integr Med.2015 Dec 1;12(4):267-75. doi: 10.1515/jcim-2014-0023.
• BACKGROUND: Medicinal plants have been used for centuries and have become part of complementary medicine worldwide because of their health benefits. Some have been successfully used directly in the treatment and prevention of infectious diseases or indirectly by stimulating the immune system. In the
• PMID 26247508

• Immunization with Single Oral Dose of Alginate-Encapsulated BCG Elicits Effective and Long-Lasting Mucosal Immune Responses.

• Hosseini M1, Dobakhti F2, Pakzad SR3, Ajdary S1.
• Scandinavian journal of immunology.Scand J Immunol.2015 Dec;82(6):489-97. doi: 10.1111/sji.12351.
• Effective vaccination against pathogens, which enter the body through mucosal surfaces, requires the induction of both mucosal and systemic immune responses. Here, mucosal as well as systemic immune responses in the lung and spleen of BALB/c mice which were orally vaccinated with a single dose of al
• PMID 26286252

Japanese Journal

• インスリンデテミル(レベミル®)およびインスリングラルギン(ランタス®)注射部位に浸潤性紅斑を呈した 1 例

• 西日本皮膚科 78(1), 54-56, 2016
• NAID 130005152138

• ラテックスアレルギー　病態生理と診断・治療

• 日本ゴム協会誌 88(9), 351-357, 2015
• NAID 130005110046

• Oxidized dietary oils enhance immediate- and/or delayed-type allergic reactions in BALB/c mice

• Allergology International 64(1), 66-72, 2015
• NAID 130004873120

Related Links

• Delayed type allergic reaction following the use of nonlatex ...

1. Int Endod J. 2006 Jul;39(7):576-80. Delayed type allergic reaction following the use of nonlatex rubber dam during endodontic treatment. Sunay H, Tanalp J, Güler N, Bayirli G. Department of Endodontics, Faculty of Dentistry ...

• Hypersensitivity reactions - University of South Carolina

Type IV hypersensitivity is also known as cell mediated or delayed type hypersensitivity. The classical example of this hypersensitivity is tuberculin (Montoux) reaction (figure 5) which peaks 48 hours after the injection of antigen ...

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★リンクテーブル★

リンク元	「IV型アレルギー」
関連記事	「type」「delayed」「allergic」「delay」「reaction」

「IV型アレルギー」

　　[★]

英

type IV allergic reaction

同

IV型アレルギー反応、type IV hypersensitivity、遅延型アレルギー反応 delayed allergic reaction delayed type allergic reaction、遅延型過敏症 delayed-type hypersensitivity delayed type hypersensitivity DTH、遅延型過敏症アレルギー、遅延型アレルギー、遅延型過敏性免疫反応、遅延型過敏反応

関

アレルギー

概念

• 抗原特異的T細胞によって起こる細胞性免疫反応

関与する細胞・物質

• 1.

• 1) 抗原提示細胞：マクロファージ、樹状細胞
• 2) 抗原に感作されたT細胞(IV型アレルギーの原因となっているT細胞 = T_DTH)

• 2. T細胞が放出するサイトカイン(昔の言葉でリンホカイン)
• 3. 2.によって動員される細胞：T細胞、マクロファージ

アレルギー反応発現までの時間

• ピークは24-48hr　　⇔　I型アレルギーは即時

病態生理

• 体内に侵入した抗原は樹状細胞やマクロファージなどの抗原提示細胞に貪食され分解されて、MHC class IIに抗原をのせてT細胞に提示する。T細胞は感作され、再び抗原刺激を受けるとINF-γやTNF-αなどのサイトカインを産生し炎症を惹起する。この反応は抗原進入後48時間程度でピークとなる。(SPE.291)
• ここで活性化されるT細胞がTh2細胞優位である場合、I型アレルギー反応の遅延型反応のような反応を呈する。

主な疾患

• 1. 接触性皮膚炎 contact dermatitis

• アレルゲン：うるし、銀杏など、装飾品(めがね、イヤリング、時計など)、下着、外用薬、化粧品
• アレルゲンテスト：パッチテスト(皮膚貼付試験: アレルゲン貼付後24-48時間後に判定)

• 2. アトピー性皮膚炎 atopic dermatitis, atopic eczema

• I型アレルギー + IV型アレルギー

• 3. 慢性肉芽種症 chronic granuloma

• アレルゲン：結核、癩(らい)、サルコドーシスの原因となる病原体

IV型アレルギーを利用した検査

• 1. ツベルクリンテスト
• 2. 光田反応

• 癩抗原(レプラミン)注射後、硬結を判定

• 3. ディック反応

• 猩紅熱のディック毒素の判定

• 4. フライ反応

• 鼡径リンパ肉芽腫(第4性病)の判定

• 5. DNCB感作試験

「type」

　　[★]

• n.

• 型、タイプ、(生物)タイプ標本

(windows)ファイル内容表示(linux -> cat])

ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html

関

form、mode、pattern、type specimen、typed

　 　 　 　 　 　 　 　

「delayed」

　　[★]

• adj.

• 遅延性の、遅延型の、遅発性の、晩発性の、後発性の

関

delayed-type、late、late-onset、protracted、tardive、tardus、tardy

　

「allergic」

　　[★]

• adj.

• アレルギーの、アレルギー性の、アレルギー型の

関

allergy、hypersensitivity

　 　 　

「delay」

　　[★]

• adj.

• 遅延、遅れ、遅延させる、遅らせる

関

lag、retard、retardation

　 　 　 　 　

「reaction」

　　[★]

• 反応

関

react、respond、response、responsive