WordNet

write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
(biology) the taxonomic group whose characteristics are used to define the next higher taxon
a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
all of the tokens of the same symbol; "the word `element contains five different types of character"
printed characters; "small type is hard to read"
identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
(mechanics) the equal and opposite force that is produced when any force is applied to a body; "every action has an equal and opposite reaction"
a response that reveals a persons feelings or attitude; "he was pleased by the audiences reaction to his performance"; "John feared his mothers reaction when she saw the broken lamp"
a bodily process occurring due to the effect of some antecedent stimulus or agent; "a bad reaction to the medicine"; "his responses have slowed with age" (同)response
doing something in opposition to another way of doing it that you dont like; "his style of painting was a reaction against cubism"
an idea evoked by some experience; "his reaction to the news was to start planning what to do"
extreme conservatism in political or social matters; "the forces of reaction carried the election"
characterized by or caused by allergy; "an allergic reaction"
having an allergy or peculiar or excessive susceptibility (especially to a specific factor); "allergic children"; "hypersensitive to pollen" (同)hypersensitive, hypersensitized, hypersensitised, sensitized, sensitised, supersensitive, supersensitized, supersensitised
the 9th letter of the Roman alphabet (同)i
writing done with a typewriter (同)typewriting

PrepTutorEJDIC

〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
{名}(…に対する)『反応』《+『to』+『名』》 / 〈U〉(…に対する)(政治的・社会的な)『反動』,逆コース《+『against』+『名』》 / 〈U〉〈C〉化学反応,化学変化 / 〈U〉〈C〉(物理学で)反作用
アレルギー性の;(…に)アレルギーを起こす《+『to』+『名』》 / 《補語にのみ用いて》《話》(…に)神経過敏の,(…が)大きらいの《+『to』+『名』(do『ing)』》
『私は』私が
iodineの化学記号

UpToDate Contents

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1. 薬物アレルギー：分類および臨床的特徴 drug allergy classification and clinical features
2. 食物アレルギーの臨床症状：概要 clinical manifestations of food allergy an overview
3. 薬物アレルギー患者へのアプローチ an approach to the patient with drug allergy
4. IgEとアレルギー疾患の関係 the relationship between ige and allergic disease
5. 予防接種に対するアレルギー反応 allergic reactions to vaccines

English Journal

Drug Eruption Following High-calorie Infusion: A Possible Systemic Type IV Allergic Reaction to Sulphites.

Honda T1, Kitoh A, Miyachi Y, Kabashima K.
Acta dermato-venereologica.Acta Derm Venereol.2015 Oct 5;95(7):854-855. doi: 10.2340/00015555-2096.
is missing (Short communication).
PMID 25783746

Drug-induced Skin Lesions in Cynomolgus Macaques Treated with Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulators.

Palanisamy GS1, Marcek JM2, Cappon GD2, Whritenour J2, Shaffer CL3, Brady JT2, Houle C4.
Toxicologic pathology.Toxicol Pathol.2015 Oct;43(7):995-1003. doi: 10.1177/0192623315588114. Epub 2015 Jun 9.
Three orally administered metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulators caused skin lesions consistent with delayed type-IV hypersensitivity in cynomolgus macaques in 2- and 12-week toxicity studies. Several monkeys developed macroscopic skin lesions in multiple locations
PMID 26059827

CD32a antibodies induce thrombocytopenia and type II hypersensitivity reactions in FCGR2A mice.

Meyer T1, Robles-Carrillo L2, Davila M2, Brodie M2, Desai H2, Rivera-Amaya M2, Francis JL2, Amirkhosravi A2.
Blood.Blood.2015 Sep 22. pii: blood-2015-04-638684. [Epub ahead of print]
The CD32a IgG receptor (FcγRIIa) is a potential therapeutic target for diseases in which IgG immune complexes (ICs) mediate inflammation, such as heparin-induced thrombocytopenia (HIT), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE). Monoclonal antibodies (mAbs) are a promising s
PMID 26396093

Japanese Journal

ラテックスアレルギー　病態生理と診断・治療

日本ゴム協会誌 88(9), 351-357, 2015
NAID 130005110046

局所麻酔薬による遅延型アレルギーの一例

松本歯学 39(1), 12-15, 2013-06-30
NAID 120005316686

歯科に関連するⅣ型アレルギー反応 : 金属アレルギー (特集アレルギー反応とバイオマテリアル)

バイオマテリアル : 生体材料 30(2), 95-99, 2012-04
NAID 40019312208

Related Pictures

Type IV hypersensitivity reaction or Delayed type hypersensitivity (DTH) - Online Type IV Hypersensitivity | Hypersensitivity, Type iv hypersensitivity, Immunology Hypersensitivity Hypersensitivity – Exaggerated immune response that have There are FOUR Distinct Types of Allergic Reactions ~ signs and symptoms of throat Type IV Hypersensitivity Reaction | Concise Medical Knowledge Irritation and allergic reactions - Tisserand Institute

★リンクテーブル★

リンク元	「IV型アレルギー」
関連記事	「type」「I」「allergic」「reaction」「IV」

「IV型アレルギー」

　　[★]

英: type IV allergic reaction
同: IV型アレルギー反応、type IV hypersensitivity、遅延型アレルギー反応 delayed allergic reaction delayed type allergic reaction、遅延型過敏症 delayed-type hypersensitivity delayed type hypersensitivity DTH、遅延型過敏症アレルギー、遅延型アレルギー、遅延型過敏性免疫反応、遅延型過敏反応
関: アレルギー

概念

抗原特異的T細胞によって起こる細胞性免疫反応

関与する細胞・物質

1.

1) 抗原提示細胞：マクロファージ、樹状細胞
2) 抗原に感作されたT細胞(IV型アレルギーの原因となっているT細胞 = T_DTH)

2. T細胞が放出するサイトカイン(昔の言葉でリンホカイン)
3. 2.によって動員される細胞：T細胞、マクロファージ

アレルギー反応発現までの時間

ピークは24-48hr　　⇔　I型アレルギーは即時

病態生理

体内に侵入した抗原は樹状細胞やマクロファージなどの抗原提示細胞に貪食され分解されて、MHC class IIに抗原をのせてT細胞に提示する。T細胞は感作され、再び抗原刺激を受けるとINF-γやTNF-αなどのサイトカインを産生し炎症を惹起する。この反応は抗原進入後48時間程度でピークとなる。(SPE.291)
ここで活性化されるT細胞がTh2細胞優位である場合、I型アレルギー反応の遅延型反応のような反応を呈する。