複雑部分発作
WordNet
- complicated in structure; consisting of interconnected parts; "a complex set of variations based on a simple folk melody"; "a complex mass of diverse laws and customs"
- a compound described in terms of the central atom to which other atoms are bound or coordinated (同)coordination_compound
- a conceptual whole made up of complicated and related parts; "the complex of shopping malls, houses, and roads created a new town" (同)composite
- (psychoanalysis) a combination of emotions and impulses that have been rejected from awareness but still influence a persons behavior
- showing favoritism
- being or affecting only a part; not total; "a partial description of the suspect"; "partial collapse"; "a partial eclipse"; "a partial monopoly"; "partial immunity"
- a sudden occurrence (or recurrence) of a disease; "he suffered an epileptic seizure" (同)ictus, raptus
- the taking possession of something by legal process
PrepTutorEJDIC
- 『いくつかの部分から成る』,複合の,合成の / 『複雑な』,入りくんだ,こみいった(complicated) / 複合体,合成物 / コンプレックス,複合(抑圧されて心に残った複雑なしこり)
- (また『part』)『一部分の』,部分的な;不完全な / 不公平な,偏った / 《補語にのみ用いて》(…が)特に好きで《+『to』+『名』》
- 〈U〉〈C〉つかむ(つかまれる)こと / 〈U〉〈C〉強奪;差し押さえ;逮捕 / 〈C〉(病気・恐怖などが)襲うこと,発作
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/02/18 05:23:20」(JST)
[Wiki en表示]
Complex partial seizure |
Classification and external resources |
ICD-10 |
G40.2 |
ICD-9 |
345.4 |
MedlinePlus |
000699 |
eMedicine |
neuro/74 |
MeSH |
D017029 |
A complex partial seizure is an epileptic seizure that is associated with bilateral cerebral hemisphere involvement and causes impairment of awareness or responsiveness, i.e. alteration of consciousness.[1]
Contents
- 1 Presentation
- 2 See also
- 3 Notes
- 4 References
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Presentation
Complex partial seizures are often preceded by a seizure aura.[2] The seizure aura is a simple partial seizure.[2] The aura may manifest itself as a feeling of déjà vu, jamais vu, fear, euphoria or depersonalization.[3] The seizure aura might also occur as a visual disturbance, such as tunnel vision or a change in the size of objects (macropsia or micropsia).[4] Once consciousness is impaired, the person may display automatisms such as lip smacking, chewing or swallowing.[3] There may also be loss of memory (amnesia) surrounding the seizure event.[2] The person may still be able to perform routine tasks such as walking. Witnesses may not recognize that anything is wrong.
Complex partial seizures might arise from any lobe of the brain.[2] Complex partial seizures most commonly arise from the mesial temporal lobe, particularly the amygdala, hippocampus, and neocortical regions.[5] A common associated brain abnormality is mesial temporal sclerosis.[3] Mesial temporal sclerosis is a specific pattern of hippocampal neuronal loss accompanied by hippocampal gliosis and atrophy.[6] Complex partial seizures occur when excessive and synchronous electrical brain activity causes impaired awareness and responsiveness.[7] The abnormal electrical activity might spread to the rest of the brain and cause a secondary generalized tonic–clonic seizure.[8]
See also
- List of people with epilepsy
Notes
- ^ Trescher, William H., and Ronald P. Lescher 2000, p. 1748.
- ^ a b c d Trescher, William H., and Ronald P. Lescher 2000, p. 1749.
- ^ a b c Murro, Anthony M. 2006.
- ^ Engelsen, B A., C Tzoulis, B Karlsen, A Lillebø, L M 2008.
- ^ Trescher, William H., and Ronald P. Lescher 2000, p. 1750.
- ^ Trepeta, Scott 2007.
- ^ "International League Against Epilepsy." 2008.
- ^ Trescher, William H., and Ronald P. Lescher 2000, p. 1747.
References
- "International League Against Epilepsy." 2008. International League Against Epilepsy. Accessed 9 Apr. 2008 <http://www.ilae-epilepsy.org/>.
- Murro, Anthony M. "eMedicine - Complex Partial Seizures." 11 Oct. 2006. Medical College of Georgia. Accessed 9 Apr. 2008 <http://www.emedicine.com/neuro/topic74.htm>.
- Trepeta, Scott. "eMedicine - Mesial Temporal Sclerosis." 11 Sept. 2007. Jamaica Hospital. Accessed 9 Apr. 2008 <http://www.emedicine.com/radio/topic443.htm>.
- Trescher, William H., and Ronald P. Lescher. "The Epilepsies." Neurology in Clinical Practice. Ed. Walter G. Bradley, Robert B. Daroff, Gerald M. Fenichel, and C. David Marsden. Boston: Butterworth-Heinemann, 2000. 1745-1780.
Seizures and epilepsy (G40–G41, 345)
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Basics |
- Seizure types
- Seizure trigger
- Breakthrough seizure
- Postictal state
- Epileptogenesis
- Seizure prediction
- Aura (warning sign)
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Treatments |
- Antiepileptics
- Template:Anticonvulsants (for list)
- Electroencephalography (diagnosis method)
- Epileptologist
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Related disorders |
- Todd's paresis
- Landau-Kleffner syndrome
- Epilepsy in animals
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Epilepsy organizations |
- Epilepsy Foundation (USA)
- International Dravet Epilepsy Action League
- Epilepsy Toronto
- Epilepsy Research UK
- Epilepsy Action Australia
- Citizens United for Research in Epilepsy
- Epilepsy Action
- Epilepsy Society
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Issues for epileptics |
- Epilepsy and driving
- Epilepsy and employment
- Epilepsy in children
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Seizure types
Epilepsy types |
Partial/focal |
- Seizures
- Simple partial
- Complex partial
- Gelastic seizure
- Jacksonian seizure
- Epilepsy
- Temporal lobe epilepsy
- Frontal lobe epilepsy
- Rolandic epilepsy
- Nocturnal epilepsy
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Generalised |
- Tonic-clonic
- Absence seizure
- Atonic seizure
- Automatism
- Benign familial neonatal epilepsy
- Lennox-Gastaut
- West
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Status epilepticus |
- Epilepsia partialis continua
- Complex partial status epilepticus
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Myoclonic epilepsy |
- Progressive myoclonus epilepsies
- Dentatorubral-pallidoluysian atrophy
- Unverricht-Lundborg disease
- MERRF syndrome
- Lafora disease
- Juvenile myoclonic epilepsy
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Non-epileptic seizures |
- Febrile seizure
- Psychogenic non-epileptic seizures
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anat (n/s/m/p/4/e/b/d/c/a/f/l/g)/phys/devp
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noco (m/d/e/h/v/s)/cong/tumr, sysi/epon, injr
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proc, drug (N1A/2AB/C/3/4/7A/B/C/D)
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UpToDate Contents
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English Journal
- Sequel of spontaneous seizures after kainic acid-induced status epilepticus and associated neuropathological changes in the subiculum and entorhinal cortex.
- Drexel M, Preidt AP, Sperk G.SourceDepartment of Pharmacology, Innsbruck Medical University, Peter-Mayr-Str. 1a, 6020 Innsbruck, Austria.
- Neuropharmacology.Neuropharmacology.2012 Oct;63(5):806-17. Epub 2012 Jun 18.
- Injection of the seaweed toxin kainic acid (KA) in rats induces a severe status epilepticus initiating complex neuropathological changes in limbic brain areas and subsequently spontaneous recurrent seizures. Although neuropathological changes have been intensively investigated in the hippocampus pro
- PMID 22722023
- Tuberculoma of the brain with unknown primary infection in an immunocompetent host.
- Madhavan K, Widi G, Shah A, Petito C, Gallo BV, Komotar RJ.SourceDepartment of Neurological Surgery, University of Miami School of Medicine, 1095 NW 14th Terrace, Room 2-06, Miami, FL 33136, USA.
- Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.J Clin Neurosci.2012 Sep;19(9):1320-2. Epub 2012 Jun 23.
- Isolated cerebral tubercular abscess is uncommon in immunocompetent hosts. Our patient had a tuberculoma with no known primary and an atypical MRI appearance. We present a 67-year-old African-American male with complex partial seizures. A CT scan of the brain revealed a new right frontal mass which
- PMID 22727748
Japanese Journal
- 症例報告 長らくパニック障害と診断されていた側頭葉てんかんの一例
- Dysembryoplastic Neuroepithelial Tumor(DNET)を伴った内側側頭葉てんかんの1例
- 藤本 礼尚,山添 知宏,榎 日出夫,岡西 徹,横田 卓也,近土 善行,山崎 まどか,山本 貴道
- 脳神経外科ジャーナル 20(10), 755-760, 2011-10-20
- はじめに:腫瘍性病変を伴った症候性てんかんのてんかん焦点は,腫瘍そのものではなくその周囲もしくは関連したネットワークに存在する.腫瘍自体を切除しても,てんかん発作は消失しない.腫瘍性病変が存在し複雑部分発作二次性全般化を呈した症例に対し,焦点診断を行った後に治療を行った.対象と方法:19歳,右利き男性.13歳発症.「頭全体が気持ち悪くなる感じ」,deja vuの後に一点凝視,流涎,口部自動症,20 …
- NAID 110008750601
Related Links
- A complex partial seizure is an epileptic seizure that is associated with bilateral cerebral hemisphere involvement and causes impairment of awareness or responsiveness, i.e. alteration of consciousness.
- Absence Seizures · Atypical Absence Seizures · Myoclonic Seizures · Atonic Seizures · Tonic Seizures · Clonic Seizures · Tonic-clonic Seizures · Simple Partial Seizures · Complex Partial Seizures · Secondarily Generalized Seizures · New ...
Related Pictures
★リンクテーブル★
[★]
- 英
- epilepsy
- ラ
- epilepsia
- 同
- 癲癇
- 関
- 抗てんかん薬、てんかん発作 seizure
091009 III
- 大脳灰白質神経細胞の過剰で無秩序な電気的発射による
WHOの定義
- さまざまな原因で起こる慢性の脳疾患で、大脳神経細胞の過剰な放電からくる繰り返す発作(てんかん発作)を主な徴候とし、多種多様な臨床及び検査所見を伴う
分類
-
- 1. 運動徴候を有するもの
- 2. 知覚症状を有するもの
- 3. 自律神経症状ないし徴候を有するもの
- 4. 精神症状を有するもの
-
- a. 単純部分発作で発症し、意識障害が次に続く
- b. 自動症を伴う
- 1. 単純部分発作で全身発作に進展
- 2. 複雑郡分発作で全身発作に進展
- 3. 単純部分発作で複雑部分発作、全身発作へと進展
- 全般発作 primarily generalized seizure
- 未分類てんかん発作 unclassified seizure
てんかん、てんかん症候群および発作性関連疾患の分類(1989) (PED.1424)
-
-
- 3. 焦点性か全般性かを決定できないてんかん及び症候群
-
単純化
- 特発性全般性てんかん
- 特発性局所関連性てんかん:大脳の特定の位置に焦点がある
- 症候性全般性てんかん
- 症候性局所関連性てんかん:大脳の特定の位置に焦点がある
疫学
- 200人に1人 (0.5%)
- 人口1000対3-10(0.3-1.0%) (PSY.376)
病因
-
- 出産障害(酸素不足)、先天性異常、熱性血栓症
- 外傷、腫瘍
- GABA作動性ニューロンなどの抑制性のニューロンは損傷を受けやすい→ニューロンの過剰興奮につながる
症状
- post ictal state:もうろうとした状態。
- postictal psychosis:発作後精神病はてんかんの発作後に幻覚妄想状態が出現するものであり、数時間から数日の経過で消退する。
- 慢性経過のてんかんで幻覚妄想状態が出現しうる、らしい。
診断
- てんかん発作→バイタルサインの確認→医療面接→身体所見・神経学的所見
医療面接
病歴の問診
- てんかん治療ガイドライン2010
- 発作の頻度
- 発作の状況と誘因(光過敏性など)
- 発作の前および発作中の症状(身体的,精神的症候および意識障害)
- 症状の持続
- 発作に引き続く症状
- 外傷,咬舌,尿失禁の有無
- 発作後の頭痛と筋肉痛
- 複数回の発作のある患者では初発年齢
- 発作および発作型の変化・推移
- 最終発作
- 発作と覚醒・睡眠との関係
身体所見・神経学的所見
- 1. 外傷、咬舌の有無
- 2. 尿失禁の有無
- 3. 意識レベル:発作時の意識の有無、post ictal state(発作後のもうろう状態)
- 4. 眼位:眼球偏倚(皮質注視中枢が興奮することにより、病側と反対側を見つめる)
- 5. 局所神経症状の有無
治療
[★]
- 英
- absence seizure
- 同
- アプサンス、アブサンス
- 関
- てんかん、異常脳波、小発作、阻害、抗てんかん薬
疫学
誘因
症状
予後
- 知能正常
- 良好。大発作を合併する場合には予後が悪くなる
治療
- 無効:フェノバルビタール、フェニトイン、カルバマゼピン
Nelson. 2462
- absence seizureでは毎日いくどなく発作が起きる
- complex partial seizureはそれほど頻繁には起きない
- 発作時には体の緊張は失われないが、頭がわずかに前にたおれることも
- 発作後には損傷が起きたようなにえない。
- 自動的な行動をしばしば伴う。
- 3-4分間過換気がassence発作を起こす
脳波
<youtube>http://www.youtube.com/watch?v=H3iLQi6wt94</youtube>
<youtube>http://www.youtube.com/watch?v=BzIs8YeafZM</youtube>
[★]
- 英
- complex partial seizure, CPS
- 関
- てんかん発作、精神運動発作、側頭葉てんかん
概念
焦点
- 一側側頭葉の内側部(扁桃核-海馬 ← 最も多い)、外側部(側頭葉皮質、島)
- その他の部位
症例
- 11歳男児。数ヶ月前から時々舌打ちをしたり、無目的な徘徊をするようになったことに母親が気づき来院した。症状の持続時間は2分であり、その間の記憶はない。脳波では側頭葉に棘波を認める。
[★]
複雑部分発作
- 関
- complex partial seizure
[★]
- 関
- complexes、complicated、composite、conjugate、intricate
[★]
- 関
- division、in part、moiety、part、partially、partly、piece、portion、region
[★]
- 関
- hybrid、mixed lineage、mixed type、mixed-type
[★]
- 関
- complex、composite
[★]
てんかん発作