1. any of a class of drugs used to treat depression; often have undesirable side effects (同)antidepressant_drug


  1. 抗抑鬱(うつ)剤(鬱病の治療薬)

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/09/02 20:44:49」(JST)

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English Journal

  • Neoechinulin A induced memory improvements and antidepressant-like effects in mice.
  • Sasaki-Hamada S1, Hoshi M1, Niwa Y1, Ueda Y1, Kokaji A1, Kamisuki S2, Kuramochi K3, Sugawara F2, Oka J4.
  • Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2016 Nov 3;71:155-61. doi: 10.1016/j.pnpbp.2016.08.002. Epub 2016 Aug 2.
  • Neoechinulin A is an isoprenyl indole alkaloid that exhibits scavenging, neurotrophic factor-like, and anti-apoptotic activities. However, the effectiveness of neoechinulin A in animal models of disease has not yet been explored. In the present study, we investigated the effects of neoechinulin A on
  • PMID 27495355
  • Treatment of depression with low-strength transcranial pulsed electromagnetic fields: A mechanistic point of view.
  • van Belkum SM1, Bosker FJ2, Kortekaas R3, Beersma DG4, Schoevers RA5.
  • Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2016 Nov 3;71:137-43. doi: 10.1016/j.pnpbp.2016.07.006. Epub 2016 Jul 21.
  • BACKGROUND: Mood disorders constitute a high burden for both patients and society. Notwithstanding the large arsenal of available treatment options, a considerable group of patients does not remit on current antidepressant treatment. There is an urgent need to develop alternative treatment strategie
  • PMID 27449361
  • Abnormal cerebellar volume in acute and remitted major depression.
  • Depping MS1, Wolf ND2, Vasic N3, Sambataro F4, Hirjak D1, Thomann PA1, Wolf RC5.
  • Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2016 Nov 3;71:97-102. doi: 10.1016/j.pnpbp.2016.06.005. Epub 2016 Jun 16.
  • Abnormal cortical volume is well-documented in patients with major depressive disorder (MDD), but cerebellar findings have been heterogeneous. It is unclear whether abnormal cerebellar structure relates to disease state or medication. In this study, using structural MRI, we investigated cerebellar v
  • PMID 27321187

Japanese Journal

  • 症例報告 重度の老年期精神病性うつ病にduloxetineの単剤療法が奏効した1例
  • オピオイド受容体をターゲットとした向精神薬の可能性 (特集 分子精神医学の最前線)
  • 髄膜腫に伴う精神病性うつ病の1例

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Antidepressant Pill Antidepressant  disputes claim against antidepressantAntidepressant Medication antidepressant Are Anti-Depressant Drugs The Reason Why  You Need an Antidepressant?: Glamour.comTricyclic+Antidepressants.jpg

リンク元抗うつ薬」「向精神薬」「thymoleptic」「抗うつ剤」「antidepressive agent
拡張検索antidepressant drug



antidepressant, antidepressants


三環系抗うつ薬 tricyclic antidepressant

  • 2つの説がある。
  • 1. (急性作用)シナプス前膜におけるノルアドレナリン、セロトニンの再取り込み↓→シナプス間隙における薬剤濃度↑
  • 2. (慢性作用)(2週間後)シナプス後膜における受容体の数↓
  • 慢性作用はシナプス間隙のノルアドレナリン、セロトニン濃度が上昇した結果、シナプス後膜の受容体が減少したために出現すると考えられる。


  • 三環系
  • 四環系
ミルナシプラン milnacipran
  • 非定型抗うつ薬 atypical agent



psychotropic drug, psychotropic drugs, psychotropic agent, psychoactive drug, psychotropic, psychotropics

  • 中枢神経系に作用して精神機能に影響を及ぼす薬物の総称





antidepressantantidepressant drugantidepressive agent



antidepressantantidepressant drug

antidepressive agent」


antidepressantantidepressant drugthymoleptic

antidepressant drug」


antidepressantantidepressive agentthymoleptic