カルジオバクテリウム、カルジオバクテリウム属、Cardiobacterium属
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/13 18:14:59」(JST)
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| Cardiobacterium hominis | 
|  | 
| Cardiobacterium hominis on blood agar plate | 
| Scientific classification | 
| Kingdom: | Bacteria | 
| Phylum: | Proteobacteria | 
| Class: | Gammaproteobacteria | 
| Order: | Cardiobacteriales | 
| Family: | Cardiobacteriaceae | 
| Genus: | Cardiobacterium | 
| Species: | hominis | 
 
Cardiobacterium hominis is a Gram-negative rod commonly grouped with other bacteria into the HACEK group. It is one of several bacteria normally present in the mouth and upper part of the respiratory tract such as nose and throat. However, it may also rarely cause endocarditis, an infection of the heart valves.[1]
Contents
- 1 Microbiology
- 2 Antibiotic sensitivity
- 3 References
- 4 External links
 
Microbiology
C. hominis is a catalase-negative, oxidase-positive, indole-producing Gram-negative rod.[2] Its morphology has classically been described as highly pleomorphic and irregularly staining, although homogeneous bacilli with uniform shapes may be seen with the addition of yeast extract.[2]
Antibiotic sensitivity
Historically C. hominis has been sensitive to penicillin and penicillin derivatives such as ampicillin.[3] However, penicillin-resistant strains, including those that produce beta-lactamases, have been described with increasing frequency.[4] Clinical guidelines thus recommend that C. hominis and other HACEK organisms be presumed to harbor ampicillin resistance and therefore be treated with a third-generation cephalosporin.[3] C. hominis and other HACEK organisms also exhibit in vitro susceptibility to trimethoprim-sulfamethoxazole, fluoroquinolones, and aztreonam.[3] C. hominis is often resistant to erythromycin.[5] Since cefotaxime use may be not appropriate for C. hominis endocarditis, an alternative regimen might include association of co-amoxiclav and gentamicin.[6]
References
- ^ Malani, AN; Aronoff, DM; Bradley, SF; Kauffman, CA (September 2006). "Cardiobacterium hominis endocarditis: Two cases and a review of the literature". European Journal of Clinical Microbiology & Infectious Diseases 25 (9): 587–95. doi:10.1007/s10096-006-0189-9. PMC 2276845. PMID 16955250. Retrieved 2010-03-15. 
- ^ a b Savage, DD; Kagan, RL; Young, NA; Horvath, AE (January 1977). "Cardiobacterium hominis endocarditis: Description of two patients and characterization of the organism". Journal of Clinical Microbiology 5 (1): 75–80. PMC 274535. PMID 833269. Retrieved 2010-03-15. 
- ^ a b c Wilson, WR; Karchmer, AW; Dajani, AS; Taubert, KA; et al. (December 1995). "Antibiotic treatment of adults with infective endocarditis due to streptococci, enterococci, staphylococci, and HACEK microorganisms. American Heart Association". JAMA 274 (21): 1706–13. doi:10.1001/jama.274.21.1706. PMID 7474277.  
- ^ Lu, PL; Hsueh, PR; Hung, CC; Teng, LJ; et al. (May 2000). "Infective endocarditis complicated with progressive heart failure due to beta-lactamase-producing Cardiobacterium hominis". Journal of Clinical Microbiology 38 (5): 2015–7. PMC 86656. PMID 10790145. Retrieved 2010-03-15. 
- ^ Pfaller, Michael A.; Murray, Patrick R.; Rosenthal, Ken S. (2009). Medical Microbiology. Philadelphia: Mosby / Elsevier. p. 374. ISBN 0-323-05470-6. 
- ^ Torok, Estee; Moran, Ed; Cooke, Fiona (2009). Oxford Handbook of Infectious Diseases and Microbiolology. Oxford University Press. ISBN 9780198569251. [full citation needed]
 
External links
- Image: Cardibacterium hominins
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Infectious diseasesBacterial disease: Proteobacterial G−
primarily A00–A79, 001–041, 080–109 |  
|  |  
| α | 
| Rickettsiales | 
| Rickettsiaceae/ (Rickettsioses)
 | 
| Typhus | 
Rickettsia typhi
Rickettsia prowazekii
Epidemic typhus, Brill–Zinsser disease, Flying squirrel typhus |  
|  |  
| Spotted fever
 | 
| Tick-borne | 
Rickettsia rickettsii
Rocky Mountain spotted feverRickettsia conorii
Rickettsia japonica
Rickettsia sibirica
Rickettsia australis
Rickettsia honei
Flinders Island spotted feverRickettsia africae
Rickettsia parkeri
Rickettsia aeschlimannii
Rickettsia aeschlimannii infection |  
|  |  
| Mite-borne | 
Rickettsia akari
Orientia tsutsugamushi
 |  
|  |  
| Flea-borne |  |  |  |  
|  |  
| Anaplasmataceae | 
Ehrlichiosis: Anaplasma phagocytophilum
Human granulocytic anaplasmosis, AnaplasmosisEhrlichia chaffeensis
Human monocytotropic ehrlichiosisEhrlichia ewingii
Ehrlichiosis ewingii infection |  |  
|  |  
| Rhizobiales | 
| Brucellaceae |  |  
|  |  
| Bartonellaceae | 
Bartonellosis: Bartonella henselae
Bartonella quintana
either henselae or quintana
Bartonella bacilliformis
Carrion's disease, Verruga peruana |  |  |  
|  |  
| β | 
| Neisseriales | 
| M+ | 
Neisseria meningitidis/meningococcus
Meningococcal disease, Waterhouse–Friderichsen syndrome, Meningococcal septicaemia |  
|  |  
| M- | 
Neisseria gonorrhoeae/gonococcus
 |  
|  |  
| ungrouped: | 
Eikenella corrodens/Kingella kingae
Chromobacterium violaceum
Chromobacteriosis infection |  |  
|  |  
| Burkholderiales | 
Burkholderia pseudomallei
Burkholderia mallei
Burkholderia cepacia complexBordetella pertussis/Bordetella parapertussis
 |  |  
|  |  
| γ | 
| Enterobacteriales (OX-)
 | 
| Lac+ | 
Klebsiella pneumoniae
Rhinoscleroma, Klebsiella pneumoniaKlebsiella granulomatis
Klebsiella oxytoca 
Escherichia coli: EnterotoxigenicEnteroinvasiveEnterohemorrhagicO157:H7O104:H4
Hemolytic-uremic syndrome 
Enterobacter aerogenes/Enterobacter cloacae |  
|  |  
| Slow/weak | 
Serratia marcescens
Citrobacter koseri/Citrobacter freundii |  
|  |  
| Lac- | 
| H2S+ | 
Salmonella enterica
Typhoid fever, Paratyphoid fever, Salmonellosis |  
|  |  
| H2S- | 
Shigella dysenteriae/sonnei/flexneri/boydii
Shigellosis, Bacillary dysenteryProteus mirabilis/Proteus vulgarisYersinia pestis
Yersinia enterocolitica
Yersinia pseudotuberculosis
Far East scarlet-like fever |  |  |  
|  |  
| Pasteurellales | 
| Haemophilus: | 
H. influenzae
Haemophilus meningitisBrazilian purpuric feverH. ducreyi
H. parainfluenzae
 |  
|  |  
| Pasteurella multocida | 
PasteurellosisActinobacillus
 |  
|  |  
| Aggregatibacter actinomycetemcomitans |  |  |  
|  |  
| Legionellales | 
Legionella pneumophila/Legionella longbeachae
Coxiella burnetii
 |  
|  |  
| Thiotrichales |  |  
|  |  
| Vibrionaceae | 
Vibrio cholerae
Vibrio vulnificusVibrio parahaemolyticusVibrio alginolyticusPlesiomonas shigelloides |  
|  |  
| Pseudomonadales | 
Pseudomonas aeruginosa
Moraxella catarrhalisAcinetobacter baumannii |  
|  |  
| Xanthomonadaceae | 
Stenotrophomonas maltophilia |  
|  |  
| Cardiobacteriaceae |  |  
|  |  
| Aeromonadales | 
Aeromonas hydrophila/Aeromonas veronii
 |  |  
|  |  
| ε | 
| Campylobacterales | 
Campylobacter jejuni
Campylobacteriosis, Guillain–Barré syndromeHelicobacter pylori
Peptic ulcer, MALT lymphoma, Gastric cancerHelicobacter cinaedi
 |  |  
|  |  
| 
| Index of bacterial disease |  
|  |  
| Description |  |  
|  |  
| Disease | 
Gram-positive firmicutesGram-positive actinobacteriaGram-negative proteobacteriaGram-negative non-proteobacteriaCholeraTuberculosis |  
|  |  
| Treatment | 
Antibiotics
cell wallnucleic acidmycobacteriaprotein synthesisotherAntibodies |  |  | 
 
UpToDate Contents
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English Journal
- Construction of new cloning, lacZ reporter and scarless-markerless suicide vectors for genetic studies in Aggregatibacter actinomycetemcomitans.
- Juárez-Rodríguez MD, Torres-Escobar A, Demuth DR.SourceResearch Group in Oral Health and Systemic Disease, University of Louisville School of Dentistry, 501 S. Preston Street, Louisville, KY 40202, USA.
- Plasmid.Plasmid.2013 Jan 23. pii: S0147-619X(13)00003-6. doi: 10.1016/j.plasmid.2013.01.002. [Epub ahead of print]
- To elucidate the putative function of a gene, effective tools are required for genetic characterization that facilitate its inactivation, deletion or modification on the bacterial chromosome. In the present study, the nucleotide sequence of the Escherichia coli/Aggregatibacter actinomycetemcomitans 
- PMID 23353051
 
 
- Cerebral vasculitis and Cardiobacterium valvarum endocarditis.
- Abraham R, Irwin RB, Kannappan D, Isalska B, Koroma M, Younis N.SourceDepartment of Endocrinology, University Hospital South Manchester, Southmoor Road, Wythenshawe, Manchester M23 9LT, UK. Rabraham@doctors.org.uk
- Journal of medical microbiology.J Med Microbiol.2012 Nov;61(Pt 11):1625-30. doi: 10.1099/jmm.0.043208-0. Epub  2012 Aug 9.
- We present a case of aortic and tricuspid native valve endocarditis in which Cardiobacterium valvarum was isolated from the blood culture of a 65-year-old man. Cardiobacterium valvarum is a fastidious, Gram-negative bacillus. The genus Cardiobacterium encompasses two species - Cardiobacterium valvar
- PMID 22878249
 
 
- Impact of periodontal therapy on the subgingival microbiota of severe periodontitis: comparison between good responders and individuals with refractory periodontitis using the human oral microbe identification microarray.
- Colombo AP, Bennet S, Cotton SL, Goodson JM, Kent R, Haffajee AD, Socransky SS, Hasturk H, Van Dyke TE, Dewhirst FE, Paster BJ.SourceDepartment of Medical Microbiology, Institute of Microbiology of Federal University of Rio de Janeiro, Brazil. apcolombo@micro.ufrj.br
- Journal of periodontology.J Periodontol.2012 Oct;83(10):1279-87. Epub  2012 Feb 10.
- BACKGROUND: This study compares the changes to the subgingival microbiota of individuals with "refractory" periodontitis (RP) or treatable periodontitis (good responders [GR]) before and after periodontal therapy by using the Human Oral Microbe Identification Microarray (HOMIM) analysis.METHODS: Ind
- PMID 22324467
 
 
Related Links
- Cardiobacterium hominis is a Gram-negative rod commonly grouped with other   bacteria into the HACEK group. It is one of several bacteria normally present in   the respiratory tract. However, it may also rarely cause endocarditis, an infection   of ...
- The present case report describes the clinical course of a patient who presented   with Cardiobacterium hominis endocarditis. A review of the literature follows the   case presentation. C hominis, a fastidious Gram-negative bacillus, is a member ...
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