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1. 血栓溶解異常による血栓性および出血性疾患thrombotic and hemorrhagic disorders due to abnormal fibrinolysis [show details]
…Plasmin cleaves the polymerized fibrin strand at multiple sites and releases fibrin degradation products (FDPs). One of the major FDPs is D-dimer, which consists of two D domains from adjacent fibrin monomers…
2. 成人における確定診断を得られていない低血圧やショックの評価および初期アプローチevaluation of and initial approach to the adult patient with undifferentiated hypotension and shock [show details]
…cascade, and liver disease. Evidence of disseminated intravascular coagulation (elevated fibrin split products and D-dimer level with low fibrinogen level) can also be found in patients with severe shock …
3. 凝固検査の臨床使用clinical use of coagulation tests [show details]
…fibrinolysis . Plasmin cleaves crosslinked fibrin at multiple sites, generating other fibrin degradation products (FDPs), but D-dimer is the best-studied and validated for clinical assessment. Clinical uses …
4. 抗凝固剤系殺鼠剤中毒：臨床症状と診断anticoagulant rodenticide poisoning clinical manifestations and diagnosis [show details]
…bleeding, type and cross match; Urine dipstick for blood; Plasma fibrinogen and serum fibrin degradation products; Stool for guaiac; Other laboratory or imaging studies may also be indicated depending …
5. 成人における播種性血管内凝固の臨床的特徴、診断、および治療clinical features diagnosis and treatment of disseminated intravascular coagulation in adults [show details]
…Fibrinolysis – Fibrinolysis is activated at sites of thrombus formation, with generation of fibrin degradation products (FDP) that, when present in significant amounts, interfere with both fibrin clot formation …

Japanese Journal

FDPとDダイマーが偽高値を示した血管免疫芽球性T細胞リンパ腫の1症例

中澤美帆,徳竹孝好,倉島祥子,大塚翔平,小林光
医学検査 67(1), 119-123, 2018
<p>血液腫瘍性の高γグロブリン血症では，抗原抗体反応を原理とする検査項目においてしばしば非特異反応を示すことが報告されている。今回我々は，血管免疫芽球性T細胞リンパ腫（AITL）の患者において，FDPとD-Dが偽高値を示した症例を経験したので報告する。患者は60歳代女性。多発性のリンパ節腫大，皮疹，肝肺浸潤の症状で発症し，AITLと診断された。入院後9病日目に，D-Dが「プロゾン」と …
NAID 130006321454

門脈血栓症を繰り返した,抗リン脂質抗体症候群を合併した肝硬変の一例

大江真里,正月泰士,合谷猛,山下晋作,佐藤丈顕,国府島庸之,加藤正樹,Kohjima Motoyuki,Kojima Motoyuki,Kato Masaki
福岡医学雑誌 = Fukuoka acta medica 107(10), 185-190, 2016-10-25
Background : Although portal vein thrombosis in cirrhotic patients is frequently observed, the detailed process remains to be clarified, and the role of anticardiolipin antibody in the development of …
NAID 120005972904