フィブリン分解産物
WordNet
- a chemical substance formed as a result of a chemical reaction; "a product of lime and nitric acid"
- a consequence of someones efforts or of a particular set of circumstances; "skill is the product of hours of practice"; "his reaction was the product of hunger and fatigue"
- an artifact that has been created by someone or some process; "they improve their product every year"; "they export most of their agricultural production" (同)production
- a quantity obtained by multiplication; "the product of 2 and 3 is 6" (同)mathematical product
- changing to a lower state (a less respected state) (同)debasement
- a white insoluble fibrous protein formed by the action of thrombin on fibrinogen when blood clots; it forms a network that traps red cells and platelets
PrepTutorEJDIC
- 『産物』;製品 / (…の)結果,帰結《+『of』+『名』(do『ing』)》 / (数の)積 / (化学の)生成物
- (地位の)格下げ / (品位などの)下落
- (凝固血液中の)線維素,フィブリン
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/22 16:26:21」(JST)
[Wiki en表示]
Principles of D-dimer testing
Fibrin degradation product (FDPs), also known as fibrin split products, are components of the blood produced by clot degeneration.[1] Clotting, also called coagulation, at the wound site produces a mass of fibrin threads called a net that remains in place until the cut is healed. As a cut heals, the clotting slows down. Eventually the clot is broken down and dissolved by plasmin. When the clot and fibrin net dissolve, fragments of protein are released into the body. These fragments are fibrin degradation products or FDPs. If your body is unable to dissolve a clot, you may have abnormal levels of FDPs. The most notable subtype of fibrin degradation products is D-dimer.
The levels of these FDPs rise after any thrombotic event.
Fibrin and fibrinogen degradation product (FDP) testing is commonly used to diagnose disseminated intravascular coagulation.[2]
Contents
- 1 As Tumor Marker
- 2 See also
- 3 References
- 4 External links
As Tumor Marker
As Tumor Marker known as AMDL-ELISA DR-70 (FDP) and now as Onko-Sure has been approved by US FDA on July 1, 2008 for In vitro diagnostic only and serial testing for monitoring colorectal cancer with more effective by 50 percent than Carcinoembryonic antigen (CEA) when CEA values is low. Onko-Sure blood test can detect also tumors/cancers of: lung, breast, stomach, liver, colon, rectal, ovarian, esophageal, cervical, trophoblastic, thyroid, malignant lymphoma, and pancreatic.[3][4]
See also
References
- ^ Gaffney PJ, Edgell T, Creighton-Kempsford LJ, Wheeler S, Tarelli E (1995). "Fibrin degradation product (FnDP) assays: analysis of standardization issues and target antigens in plasma". Br. J. Haematol. 90 (1): 187–94. doi:10.1111/j.1365-2141.1995.tb03399.x. PMID 7786784.
- ^ Fibrin/Fibrinogen Degradation Products
- ^ "510(k) summary: AMDL-ELISA DR-70® (FDP)" (PDF). Retrieved January 4, 2014.
- ^ "Cancer Diagnostics". Retrieved January 4, 2014.
External links
- MedlinePlus Encyclopedia 003655
UpToDate Contents
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English Journal
- [Congenital hypofibrinogenemia associated with a novel mutation in FGG gene].
- Wang Y1, Ding H, Hao X, Zhu L, Yang L, Jin Y, Wang M.
- Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.Zhonghua Yi Xue Yi Chuan Xue Za Zhi.2015 Jun 10;32(3):331-4. doi: 10.3760/cma.j.issn.1003-9406.2015.03.006.
- OBJECTIVE: To identify the genetic mutation underlying congenital hypofibrinogenamia in a Chinese pedigree.METHODS: Standard coagulation tests including the prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), plasminogen activity (PLG:A), D-Dimer (DD) and fibrin
- PMID 26037343
- Clinical evaluation of eight different D-dimer tests for the exclusion of deep venous thrombosis in primary care patients.
- Oude Elferink RF1, Loot AE, Van De Klashorst CG, Hulsebos-Huygen M, Piersma-Wichers M, Oudega R.
- Scandinavian journal of clinical and laboratory investigation.Scand J Clin Lab Invest.2015 May;75(3):230-8. doi: 10.3109/00365513.2014.993697. Epub 2015 Jan 22.
- D-dimer tests are an essential element in the diagnostic work-up of deep venous thrombosis (DVT). However, the poor standardization amongst assays necessitates clinical validation before implementation in daily practice. We therefore evaluated the analytical and diagnostic performance of eight D-dim
- PMID 25608596
- Sonothrombolysis: the contribution of stable and inertial cavitation to clot lysis.
- Petit B1, Bohren Y2, Gaud E2, Bussat P2, Arditi M2, Yan F2, Tranquart F2, Allémann E3.
- Ultrasound in medicine & biology.Ultrasound Med Biol.2015 May;41(5):1402-10. doi: 10.1016/j.ultrasmedbio.2014.12.007. Epub 2015 Jan 15.
- Microbubble-mediated sonothrombolysis (STL) is a remarkable approach to vascular occlusion therapy. However, STL remains a complex process with multiple interactions between clot, ultrasound (US), microbubbles (MB) and thrombolytic drug. The aim of this study was to evaluate the ability of combining
- PMID 25601463
Japanese Journal
- Dダイマー・FDPの逆転現象に対しDTTが有用であった1症例
- 三好 雅士,松田 定信,井上 千尋,高松 典通,土井 俊夫
- 医学検査 63(1), 86-89, 2014
- … Fibrin degradation product (FDP) and D-dimer are useful fibrinolytic markers for diagnosis and therapeutic assessment in patients with disseminated intravascular coagulation (DIC) and deep vein thrombosis (DVT). … DTT is a cheap and easily available product that may be useful in the analysis of the non-specific IgM reaction to measure D-dimer. …
- NAID 130005057035
- 骨髄穿刺で診断しえた骨シンチグラフィ陰性肝細胞癌骨髄癌症の1例
- 小池 和彦,伊坪 真理子,田尻 久雄
- 肝臓 55(12), 740-748, 2014
- 症例は62歳男性.5年にわたるB型肝炎ウイルス関連肝細胞癌に対する繰り返す肝動脈塞栓術(TACE)の経過中,多発するリンパ節および骨転移を認めたためソラフェニブを導入したが,まもなく食欲不振,全身倦怠感が出現,内服中止後も改善がみられず入院となった.入院時身体所見として出血傾向を伴い,血液検査では血小板数低下,FDP 276 μg/mlまでの上昇など播種性血管内凝固症候群の徴候がみられ,末梢血への …
- NAID 130004897334
- A Case of Lemierre's Syndrome Following Cervical Cellulitis due to Community-acquired Methicillin-resistant Staphylococcus aureus Infection
- , , , , ,
- 耳鼻咽喉科臨床 補冊 138(0), 124-125, 2014
- … Laboratory data showed an increase in white blood cells, C-reactive protein, D dimer and fibrin degradation product. …
- NAID 130004834008
Related Links
- fibrin/fibrinogen degradation product n. Any of several poorly characterized small peptides produced following the action of plasmin on fibrinogen and fibrin. ... Disclaimer All content on this website, including dictionary, thesaurus ...
- fibrin/fibrinogen degradation product n. Any of several poorly characterized small peptides produced following the action of plasmin on fibrinogen and fibrin.
Related Pictures
★リンクテーブル★
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- 英
- fibrin degradation product FDP,fibrinogen degradation product
- 同
- フィブリン体分解産物 fibrinogen split products fibrin split products、フィブリン分解物、fibrinogen and fibrin degradation products
- 関
- [[]]
-fibrin degradation product
- 同
- FDP
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- 同
- フィブリン/フィブリノゲン分解産物
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- 関
- breakdown、catabolize、catabolized、crack、decay、decompose、decomposition、degrade、depolymerization、depolymerize、disassemble、disassembly、disintegrate、disintegration、resolve
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- 関
- accomplishment、achievement、consequence、outcome、output、result、resultant、sequence
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- 関
- catabolite、decomposition product