WordNet

with pain or distress or bitterness; "he took the rejection very hard"
(of light) transmitted directly from a pointed light source (同)concentrated
with firmness; "held hard to the railing" (同)firmly
very strong or vigorous; "strong winds"; "a hard left to the chin"; "a knockout punch"; "a severe blow" (同)knockout, severe
causing great damage or hardship; "industries hit hard by the depression"; "she was severely affected by the banks failure" (同)severely
being distilled rather than fermented; having a high alcoholic content; "hard liquor" (同)strong
unfortunate or hard to bear; "had hard luck"; "a tough break" (同)tough
(of speech sounds); produced with the back of the tongue raised toward or touching the velum; "Russian distinguished between hard consonants and palatalized or soft consonants"
dispassionate; "took a hard look"; "a hard bargainer";
dried out; "hard dry rolls left over from the day before"
earnestly or intently; "thought hard about it"; "stared hard at the accused"
into a solid condition; "concrete that sets hard within a few hours"
resisting weight or pressure
slowly and with difficulty; "prejudices die hard"
to the full extent possible; all the way; "hard alee"; "the ship went hard astern"; "swung the wheel hard left"
very near or close in space or time; "it stands hard by the railroad tracks"; "they were hard on his heels"; "a strike followed hard upon the plants opening"
with effort or force or vigor; "the team played hard"; "worked hard all day"; "pressed hard on the lever"; "hit the ball hard"; "slammed the door hard"
cause mental pain to; "The news of her childs illness distressed the mother"
a state of adversity (danger or affliction or need); "a ship in distress"; "she was the classic maiden in distress"
extreme physical pain; "the patient appeared to be in distress"
the seizure and holding of property as security for payment of a debt or satisfaction of a claim; "Originally distress was a landlords remedy against a tenant for unpaid rents or property damage but now the landlord is given a landlords lien" (同)distraint
psychological suffering; "the death of his wife caused him great distress" (同)hurt, suffering
the physical property of being stiff and resisting bending (同)rigidness
to cause inconvenience or discomfort to; "Sorry to trouble you, but..." (同)put_out, inconvenience, disoblige, discommode, incommode, bother
cause bodily suffering to and make sick or indisposed (同)ail, pain
an unwanted pregnancy; "he got several girls in trouble"
an effort that is inconvenient; "I went to a lot of trouble"; "he won without any trouble"; "had difficulty walking"; "finished the test only with great difficulty" (同)difficulty
a source of difficulty; "one trouble after another delayed the job"; "whats the problem?" (同)problem
an event causing distress or pain; "what is the trouble?"; "heart trouble"
a condition or state of affairs almost beyond ones ability to deal with and requiring great effort to bear or overcome; "grappling with financial difficulties"
the quality of being difficult; "they agreed about the difficulty of the climb" (同)difficultness
a factor causing trouble in achieving a positive result or tending to produce a negative result; "serious difficulties were encountered in obtaining a pure reagent"
difficult to accomplish; demanding considerable mental effort and skill; "the arduous work of preparing a dictionary"
characterized by effort to the point of exhaustion; especially physical effort; "worked their arduous way up the mining valley"; "a grueling campaign"; "hard labor"; "heavy work"; "heavy going"; "spent many laborious hours on the project"; "set a punishing pace" (同)backbreaking, grueling, gruelling, hard, heavy, laborious, operose, punishing, toilsome
taxing to the utmost; testing powers of endurance; "his final, straining burst of speed"; "a strenuous task"; "your willingness after these six arduous days to remain here"- F.D.Roosevelt (同)straining, strenuous
not tractable; difficult to manage or mold; "an intractable disposition"; "intractable pain"; "the most intractable issue of our era"; "intractable metal"
not easy; requiring great physical or mental effort to accomplish or comprehend or endure; "a difficult task"; "nesting places on the cliffs are difficult of access"; "difficult times"; "why is it so hard for you to keep a secret?" (同)hard
the process of becoming hard or solid by cooling or drying or crystallization; "the hardening of concrete"; "he tested the set of the glue" (同)solidifying, solidification, set, curing
abnormal hardening or thickening of tissue
the act of making something harder (firmer or tighter or more compact)
a lightweight protective helmet (plastic or metal) worn by construction workers (同)tin_hat, safety hat
of animals or plants that have a hard shell

PrepTutorEJDIC

(物体が)『堅い』,(手触りが)堅固な,しっかりした / 『難しい』,努力を要する / 《名詞の前にのみ用いて》(人が)『精力的な』,勤勉な / 激しい,猛烈な / (生活などが)耐え難い,つらい / (季節・天候などが)厳しい;(雨・風などが)激しい / (人が)厳格な;(行為などが)容赦しない,無情な / (方針・条件などが)妥協(譲歩)しない,厳しい / (感情が)うらみを含む,憤然とした / (体が)筋肉質の,がんじょうな / (紙幣に対して)硬貨の,(小切手などに対して)現金の;(貨幣が)容易に兌換(だかん)できる / (子音が)硬音の(c,gがcome, goのように[k],[g]と発音される) / アルコール分の多い / (水が)硬質の / (エックス線が)透過能力が大きい / 一生懸命に,『熱心に』 / 『強く』,激しく,大いに / やっと,かろうじて / 『堅く』 / ひどく悲んで / 接近して
〈U〉(肉体的・精神的な)『激しい苦しみ』,苦痛,苦悩,非嘆 / 《a~》(…にとっての)悩みの種《+『to』+『名』》 / 〈U〉『貧苦』,窮乏 / 〈U〉『危険状態』,難儀 / (精神的・肉体的に)〈人〉‘を'『苦しめる』,苦悩させる
三いこと,硬直 / 厳格;厳密,厳正
〈U〉『苦難』,心配,悩み / 〈C〉『苦労の種』,心配事,悩みの種 / 〈U〉危険[な状態],困難 / 〈U〉『骨折り』,手数,めんどう,迷惑 / 〈C〉〈U〉(政治的・社会的)紛争,騒動 / 〈U〉(機械などの)故障 / 〈C〉〈U〉病気 / 〈事が〉〈人・自分〉‘を'『悩ます』,心配させる,苦しめる / 《物事を頼むときていねいに》〈人〉‘を'『わずらわす』,じゃまする / 〈水・空気など〉‘を'かき乱す / 《おもに疑問文・否定文で》心配する,気を遣う;骨を折る
〈U〉『難しさ』,困難 / 〈C〉『困難なこと』,難事,障害 / 〈C〉《通例複数形で》『困難な状況』,(特に)財政困難 / 〈C〉〈U〉(…との)不和,仲たがい《+『with』(『between』)+『名』》 / 〈C〉苦情,反対
骨の折れる,困難な / (山などが)登りにくい,けわしくて骨の折れる / (努力などが)しんぼう強い,奮闘する(strenuous)
(人・人の性質が)手に負えない,強情な / (物事が)処理しにくい,取り扱いにくい
(物事が)『難しい』,困難な,骨の折れる / (人が)『気難しい』,つきあいにくい,扱いにくい
無煙炭
おや,はああ,ああ(驚き・喜び・疑い・ためらいなどを表す声)
hectare; hectares

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/24 11:33:08」(JST)

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1. 早期（ステージIおよびII）の頭頸部癌の治療：口腔 treatment of early stage i and ii head and neck cancer the oral cavity
2. 局所進行性（ステージIIIおよびIV）の頭頸部癌の治療：口腔 treatment of locoregionally advanced stage iii and iv head and neck cancer the oral cavity
3. 頭頸部癌患者における下顎および口蓋再建 mandibular and palatal reconstruction in patients with head and neck cancer
4. 後天性上顎欠損のマネージメント：頭頸部癌手術後の補綴学的リハビリテーション management of acquired maxillary defects prosthetic rehabilitation after head and neck cancer surgery
5. 頭頚部癌の診断および病期分類の概要 overview of the diagnosis and staging of head and neck cancer

English Journal

Enhancing research capacity for global health: evaluation of a distance-based program for international study coordinators.

Wilson LL, Rice M, Jones CT, Joiner C, Laborde J, McCall K, Jester PM, Carter SC, Boone C, Onwuzuligbo U, Koneru A.SourceProfessor and Assistant Dean for International Affairs, University of Alabama at Birmingham School of Nursing. Lyndawilson@uab.edu.
The Journal of continuing education in the health professions.J Contin Educ Health Prof.2013 Dec;33(1):67-75. doi: 10.1002/chp.21167.
INTRODUCTION: Due to the increasing number of clinical trials conducted globally, there is a need for quality continuing education for health professionals in clinical research manager (CRM) roles. This article describes the development, implementation, and evaluation of a distance-based continuing
PMID 23512562

Adenomyoepithelial adenosis associated with breast cancer: a case report and review of the literature.

Maeda H, Yokoi S, Nakazawa M, Koneri K, Imamura Y, Yamaguchi A.SourceFirst Department of Surgery, Faculty of Medicine, University of Fukui, 23-3, Matsuoka, Shimoaizuki, Eiheiji-cho, Yoshida-gun, 910-1193 Fukui, Japan.
SpringerPlus.Springerplus.2013 Dec;2(1):50. Epub 2013 Feb 13.
Adenomyoepithelial adenosis of the breast is an extremely rare type of adenosis. We herein present the case of a 35-year-old woman, who presented with a small painless hard lump and elastic soft induration of 5 cm in diameter in her left breast. Clinical examination and diagnostic workup were sugge
PMID 23450635

Effect of salt solutions applied during wheat conditioning on lipase activity and lipid stability of whole wheat flour.

Doblado-Maldonado AF, Arndt EA, Rose DJ.SourceDepartment of Food Science & Technology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Food chemistry.Food Chem.2013 Sep 1;140(1-2):204-9. doi: 10.1016/j.foodchem.2013.02.071. Epub 2013 Feb 26.
Lipolytic activity in whole wheat flour (WWF) is largely responsible for the loss in baking quality during storage. Metal ions affect the activity of seed lipases; however, no previous studies have applied this information to WWF in a way that reduces lipase activity, is practical for commercial man
PMID 23578634

Biochemical and physical changes of grass carp (Ctenopharyngodon idella) fillets stored at -3 and 0°C.

Liu D, Liang L, Xia W, Regenstein JM, Zhou P.SourceState Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Jiangsu Province, Wuxi 214122, China.
Food chemistry.Food Chem.2013 Sep 1;140(1-2):105-14. doi: 10.1016/j.foodchem.2013.02.034. Epub 2013 Feb 19.
The objective of this study was to investigate the effect of superchilling at -3°C compared with ice storage at 0°C on the biochemical and physical properties of grass carp fillets. Fillets stored at -3°C showed significant changes in whiteness, drip loss and textural hardness, while changes in p
PMID 23578621