網膜中心静脈閉塞症, CRVO
WordNet
- make a veinlike pattern
- any of the vascular bundles or ribs that form the branching framework of conducting and supporting tissues in a leaf or other plant organ (同)nervure
- one of the horny ribs that stiffen and support the wing of an insect (同)nervure
- a layer of ore between layers of rock (同)mineral vein
- a blood vessel that carries blood from the capillaries toward the heart; "all veins except the pulmonary vein carry unaerated blood" (同)vena, venous blood vessel
- a distinctive style or manner; "he continued in this vein for several minutes"
- in or near a center or constituting a center; the inner area; "a central position"
- a workplace that serves as a telecommunications facility where lines from telephones can be connected together to permit communication (同)telephone exchange, exchange
- closure or blockage (as of a blood vessel)
- (dentistry) the normal spatial relation of the teeth when the jaws are closed
- in or relating to the retina of the eye; "retinal cells"
- the innermost light-sensitive membrane covering the back wall of the eyeball; it is continuous with the optic nerve
PrepTutorEJDIC
- 〈C〉『静脈』 / 〈C〉(植物の)葉脈;(昆虫の)翅脈;(石の)石理;(木の)木目 / 〈C〉岩脈,鉱脈 / 〈U〉《しばしば a vein》(…の)傾向,性質《+of+名》 / 〈U〉《the vein》(…に対する)気分,気持ち《+for+名(doing)》
- 『中心の』,中央の,中心からの / 『主要な』,中心的な(main) / (音声が)中舌音の / 電話交換局(《英》[telephone]exchange)
- (目の)網膜
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/05/25 17:57:37」(JST)
[Wiki en表示]
Central retinal vein occlusion |
Classification and external resources |
Diagram of the eye; retinal vein is number 21.
|
ICD-10 |
H34.8 |
ICD-9 |
362.35 |
DiseasesDB |
11421 |
MedlinePlus |
007330 |
MeSH |
D012170 |
The central retinal vein is the venous equivalent of the central retinal artery and, like that blood vessel, it can suffer from occlusion (central retinal vein occlusion, also CRV[1]), similar to that seen in ocular ischemic syndrome. Since the central retinal artery and vein are the sole source of blood supply and drainage for the retina, such occlusion can lead to severe damage to the retina and blindness, due to ischemia (restriction in blood supply) and edema (swelling).[2]
It can also cause glaucoma.
Nonischemic CRVO is the milder form of the disease. It may progress to the more severe ischemic type.[3]
Contents
- 1 Treatment
- 2 See also
- 3 References
- 4 External links
Treatment
Treatment consists of Anti-VEGF drugs like Lucentis or intravitreal steroid implant (Ozurdex) and Pan-Retinal Laser Photocoagulation usually. Underlying conditions also require treatment. Non-Ischemic CRVO has better visual prognosis than Ischemic CRVO.
A systematic review studied the effectiveness of the anti-VEGF drugs ranibizumab and pagatanib sodium for patients suffering from non-ischemic CRVO.[4] Though there was a limited sample size, participants in both treatment groups showed improved visual acuity over 6 month periods, with no safety concerns.[4]
See also
- Macular edema
- Ischemic optic neuropathy
- Branch retinal vein occlusion
- Lucentis
- Iridodialysis
References
- ^ Ophthalmology at a Glance, Jane Olver & Lorraine Cassidy, Blackwell Science 2005.
- ^ Hayreh SS, Zimmerman MB, Podhajsky P. "Incidence of various types of vein occlusion and their recurrent demographic characteristics." Am J Ophthalmol. 1994; 117:429-441.
- ^ http://emedicine.medscape.com/article/1223746-overview
- ^ a b Braithwaite T, Nanji AA, Greenberg PB (2010). "Anti-vascular endothelial growth factor for macular edema secondary to central retinal vein occlusion". Cochrane Database Syst Rev 10: CD007325. doi:10.1002/14651858.CD007325.pub2. PMID 20927757.
External links
- Central retinal vein occlusion at Medscape. 2009
UpToDate Contents
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English Journal
- Risk Factors and Treatment Strategies in Patients With Retinal Vascular Occlusions.
- Chapin J1, Carlson K2, Christos PJ3, DeSancho MT2.
- Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.Clin Appl Thromb Hemost.2015 Oct;21(7):672-7. doi: 10.1177/1076029613513320. Epub 2013 Dec 11.
- Retinal vein occlusion (RVO) and retinal artery occlusion (RAO) cause significant visual impairment. The role of thrombophilia and cardiovascular testing is uncertain, and optimal treatment strategies have not been determined. We reviewed medical records of 39 patients with RVO and RAO (23 women and
- PMID 24335246
- Detection and Differentiation of Intraretinal Hemorrhage in Spectral Domain Optical Coherence Tomography.
- Munk MR1, Dunavoelgyi R1, Baratsits M1, Matt G1, Montuoro A1,2, Buehl W1, Schmidt-Erfurth U1, Sacu S1; Macula Study Group.
- Current eye research.Curr Eye Res.2015 Oct;40(10):1046-54. doi: 10.3109/02713683.2014.971931. Epub 2014 Oct 20.
- PURPOSE: The purpose of this study was to classify and detect intraretinal hemorrhage (IRH) in spectral domain optical coherence tomography (SD-OCT).METHODS: Initially the presentation of IRH in BRVO-patients in SD-OCT was described by one reader comparing color-fundus (CF) and SD-OCT using dedicate
- PMID 25329527
- Venous oxygen saturation is reduced and variable in central retinal vein occlusion.
- Eliasdottir TS1,2,3, Bragason D4, Hardarson SH5,4, Kristjansdottir G5, Stefánsson E5,4.
- Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie.Graefes Arch Clin Exp Ophthalmol.2015 Oct;253(10):1653-61. doi: 10.1007/s00417-014-2849-2. Epub 2014 Nov 18.
- PURPOSE: To estimate the presence and variability of retinal hypoxia in patients with central retinal vein occlusion (CRVO).METHOD: Hemoglobin oxygen saturation was measured in retinal vessels of both eyes in 14 patients with unilateral CRVO. The noninvasive spectrophotometric retinal oximeter is ba
- PMID 25404523
Japanese Journal
- 若年者の虚血型網膜中心静脈閉塞症に対する放射状視神経乳頭切開術の長期経過
- 東 寛子/山本 香織/堀 貞夫
- 東京女子医科大学雑誌 82(E1), E273-E279, 2012-01-31
- … 緒言:若年者の虚血型の網膜中心静脈閉塞症 (central retinal vein occlusion: CRVO) に対して、放射状視神経乳頭切開術(radial optic neurotomy: RON)を施行し長期経過観察が可能であった症例を報告する。 …
- NAID 110008767991
- レーザースペックルフローグラフィーにより血行動態を観察した特発性血小板減少性紫斑病(ITP)に合併した切迫型網膜中心静脈閉塞症の1例
- 新井 歌奈江/小暮 朗子/小野 まどか/田村 明子/堀 貞夫
- 東京女子医科大学雑誌 82(E1), E254-E259, 2012-01-31
- 目的:レーザースペックルフローグラフィー(LSFG)による切迫型網膜中心静脈閉塞症の血流動態の観察を行ったので報告する。,症例:30歳の女性。特発性血小板減少紫斑病の診断にてステロイドパルス療法を受けていた。治療4日後から左眼視野に光視症を主訴に当科受診した。視力は良好であったが、左眼網膜静脈は拡張、蛇行し、フルオレセイン蛍光眼底造影(FA)にて腕網膜時間の遅延を認めた。LSFGでは、右眼と比較し …
- NAID 110008767987
Related Links
- Central retinal vein occlusion (CRVO) is a common retinal vascular disorder. Clinically, CRVO presents with variable visual loss; the fundus may show retinal hemorrhages, dilated tortuous retinal veins, cotton-wool spots ...
- The retina—the layer of light-sensitive cells at the back of the eye—is nourished by blood flow, which provides nutrients and oxygen that nerve cells need. When there is a blockage in the veins into the retina, retinal vein occlusion may ...
Related Pictures
★リンクテーブル★
[★]
- 英
- retinal vein occlusion, obstruction of the retinal vein
分類
リスクファクター
- 参考1
- 年齢、高血圧、糖尿病、喫煙、肥満、凝固亢進状態(factor V Leiden, activated protein C resistance)、緑内障、網膜細血管異常(retinal arteriolar abnormality)
- 出典不明
比較
- SOP.134
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網膜静脈分枝閉塞症
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網膜中心静脈閉塞症
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網膜中心動脈閉塞症
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BRVO
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CRVO
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CRAO
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概念
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網膜動静脈交差部で静脈が閉鎖
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網膜中心静脈の閉塞
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網膜中心動脈の閉塞
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疫学
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CRVOより遙かに頻度が高い
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50歳以上の中高年で高血圧症のある人に好発
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(1)血栓塞栓子、(2)乳頭内での粥状硬化、あるいは動脈炎による血管攣縮による動脈の閉塞、(3)緑内障や外力による高眼圧
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病型
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静脈うっ滞網膜症 venous stasis retinopathy:静脈拡張、出血など静脈閉塞のみを主症状とする。 出血性網膜症 hemorrhagic retinopathy:高度の血管床閉塞など動脈の循環障害を併発
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症状
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黄斑部を支配する静脈が閉塞すれば視力低下を痔核。
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無痛性の片眼性の急激な視力低下
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無痛性の高度視力障害
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眼底
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閉塞した静脈域で静脈の拡張し、透過性亢進による出血、浮腫、綿花白斑を生じる。数ヶ月の経過で出血は吸収され、静脈は白線化し、硬性白斑が残る。
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視神経乳頭から放射状の火炎状出血、(重症例)暗赤色の出血斑。乳頭の充血、浮腫、網膜静脈の拡張蛇行、綿花様白斑、黄斑浮腫から嚢胞様黄斑浮腫
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網膜は混濁、白濁。cherry-red spot
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合併症
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新生血管形成と硝子体出血。再発性硝子体出血と牽引性網膜剥離症(閉塞した静脈域の毛細血管の閉塞によりその領域周辺の網膜や視神経乳頭での血管新生をきたす)。
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新生血管緑内障:予後不良。発症から3ヶ月が好発時期。前房隅角や虹彩に新生血管が生じ眼圧上昇をきたす。
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治療
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光凝固術:黄斑浮腫、新生血管に対して。 硝子体手術:硝子体手術、牽引性網膜剥離
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原疾患の治療 新生血管緑内障予防:汎光凝固術
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眼球圧迫マッサージ 亜硝酸アミル (高眼圧の場合)前房穿刺
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予後
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1時間以内に血行が改善しないと網膜機能の回復は期待できない。
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参考
- 1. [charged] Retinal vein occlusion: Epidemiology, clinical manifestations, and diagnosis - uptodate [1]
[★]
- 英
- central retinal vein occlusion, CRVO
- 関
- 網膜中心静脈閉塞、網膜静脈閉塞症
概念
疫学
リスクファクター
- 099C021
病型
- 静脈うっ滞網膜症 venous stasis retinopathy:静脈拡張、出血など静脈閉塞のみを主症状とする。
- 出血性網膜症 hemorrhagic retinopathy:高度の血管床閉塞など動脈の循環障害を併発
症状
合併症
- 新生血管緑内障:予後不良。発症から3ヶ月が好発時期。前房隅角や虹彩に新生血管が生じ眼圧上昇をきたす。
検査
- 眼底検査:視神経乳頭から放射状の火炎状出血、(重症例)暗赤色の出血斑。乳頭の充血、浮腫、網膜静脈の拡張蛇行、綿花様白斑、黄斑浮腫から嚢胞様黄斑浮腫 ← 網膜中心動脈閉塞症の場合は網膜は混濁、白濁。cherry-red spot
[show details]
治療
国試
[★]
- 英
- central retinal vein occlusion
- 関
- 網膜中心静脈閉塞症
[★]
網膜中心静脈閉塞症, central retinal vein occlusion
[★]
- 関
- occlude
- 関
- atresia、close、closure、dental articulation、disturb、disturbance、hamper、hindrance、impede、impediment、intercept、interception、interfere、interrupt、interruption、obliteration、obstruct、obstruction、occlude、preclusion
[★]
- 中心の、中心的な、中心性の、中枢的な、中枢性の、中枢の、中枢神経性の
- 関
- center、centrally、centrally acting、centre、centro、centrum、hub、medial、pivotal、pivotally
[★]
- 関
- 11-cis-retinal、retina、retinae、retinaldehyde, retinol
[★]
網膜静脈
- 関
- central retinal vein
[★]
静脈