非脱分極性筋弛緩薬
WordNet
- a three-dimensional shape with six square or rectangular sides (同)cube
- (computer science) a sector or group of sectors that function as the smallest data unit permitted; "since blocks are often defined as a single sector, the terms `block and `sector are sometimes used interchangeably"
- support, secure, or raise with a block; "block a plate for printing"; "block the wheels of a car"
- a solid piece of something (usually having flat rectangular sides); "the pyramids were built with large stone blocks"
- housing in a large building that is divided into separate units; "there is a block of classrooms in the west wing"
- a rectangular area in a city surrounded by streets and usually containing several buildings; "he lives in the next block" (同)city block
- an inability to remember or think of something you normally can do; often caused by emotional tension; "I knew his name perfectly well but I had a temporary block" (同)mental_block
- a number or quantity of related things dealt with as a unit; "he reserved a large block of seats"; "he held a large block of the companys stock"
- interrupt the normal function of by means of anesthesia; "block a nerve"; "block a muscle"
- run on a block system; "block trains"
- shape by using a block; "Block a hat"; "block a garment"
- shape into a block or blocks; "block the graphs so one can see the results clearly"
- stamp or emboss a title or design on a book with a block; "block the book cover"
- showing a fighting disposition; "highly competitive sales representative"; "militant in fighting for better wages for workers"; "his self-assertive and ubiquitous energy" (同)militant
- involving competition or competitiveness; "competitive games"; "to improve ones competitive position" (同)competitory
- subscribing to capitalistic competition (同)free-enterprise, private-enterprise
- a class of drugs that inhibit (block) some biological process (同)blocking_agent
- a football player whose responsibility is to block players attempting to stop an offensive play
- affecting or characteristic of both neural and muscular tissue
PrepTutorEJDIC
- (木・石などの,通例平らな面のある)『かたまり』 / 《米》(四団を街路に囲まれた)『区画』,街区 / 街区の1辺の距離(一般に40メートル前後) / 《英》ブロック(アパート・事務所・商店などに区切られている大きな建物) / 『妨害物』,障害物(obstacle);(障害によって生じた)停滞,渋滞 / 台木,台(まないた・肉切り台・まき割り台・せり売り台・帽子の木型など);《the~》炭頭台 / (特にアメリカンフットボールで)ブロック(相手の選手の突進を阻止する) / 滑車(pulley) / (座席券・株券などの)一組《+『of』+『名』》 / 〈通路など〉'を'『ふさぐ』,〈通行・進行など〉'を'妨げる / 〈帽子など〉の型取りをする / (特にアメリカンフットボールで)〈相手選手の突進〉'を'ブロックする;(ボクシングで)〈相手のパンチ〉'を'ブロックする
- 競争の,競争による
UpToDate Contents
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English Journal
Japanese Journal
- Slow Ca<SUP>2+</SUP> (RAMIC) mobilization operated by postsynaptic neuronal nicotinic receptor regulates synaptic function at the mouse neuromuscular junction
- 出崎 克也,恒枝 宏史,木村 郁子
- 日本薬理学雑誌 110(supplement), 114-119, 1997
- … mobilization was blocked by lower concentrations of competitive nAChR antagonists which did not affect the fast Ca<SUP>2+</SUP> … channel blocker tetrodotoxin prevented the generation of the slow Ca<SUP>2+</SUP> … These results suggest that RAMIC is mobilized through postsynaptic neuronal nAChR subtype to desensitize muscle nAChR at the neuromuscular junction. …
- NAID 130000752850
- Depolarizing Neuromuscular Blocking Action of Coryneine Derived from Aconite Root in Isolated Mouse Phrenic Nerve-Diaphragm Muscles
- 木村 正康,木村 郁子,室井 正志,野島 浩史,V.DIWAN Prakash
- Biological & pharmaceutical bulletin 18(5), 691-695, 1995-05-15
- … The mode of the neuromuscular blocking action of coryneine (a quaternary ammonium derivative of dopamine) derived from aconite root was investigated in isolated phrenic nerve-diaphragm muscles and denervated diaphragm muscles of mice. … These results indicate that coryneine is a depolarizing agent and a mixed-type competitive and noncompetitive neuromuscular blocker. …
- NAID 110003640911
Related Links
- Figure : Mechanism of action of competitive neuromuscular blocking drugs. These drugs thus prevent depolarization of the muscle cell membrane and inhibit muscular contraction. Because these agents compete with ...
- Atracurium: Another Competitive Neuromuscular Blocker In the US the intermediate-acting neuromuscular blocking agent, atracurium, has been made available for use as a muscle relaxant during general anaesthesia. As do other ...
★リンクテーブル★
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- 英
- nondepolarizing muscle relaxant non-depolarizing muscle relaxant
- 同
- 競合的神経筋遮断薬 competitive neuromuscular blocker、競合的筋弛緩薬 competitive muscle relaxant、非脱分極性神経筋遮断薬 non-depolarizing neuromuscular blocker、非脱分極性遮断薬 nondepolarizing blocking drugs、クラーレ様作用薬 curarimimetic、クラーレ様物質
- 関
- 脱分極性筋弛緩薬、筋弛緩薬、Train of four monitor、脱分極性遮断薬、神経筋接合部遮断薬
[show details]
- ニコチン性アセチルコリン受容体にアセチルコリンと競合的に結合することで、アセチルコリンの受容体結合を阻害
- 脱分極させることなく、アセチルコリンと競合してアセチルコリン結合部位への結合を妨げる。
- 重症筋無力症の場合、(競合してAch受容体を奪うため)少量の非脱分極性筋弛緩薬でも筋弛緩が出現 (SPC.169)
拮抗薬
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- 関
- blockade、blockage、deter、inhibit、inhibition、lump、prevent、prevention、repress、repression、seal、turn off
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- 関
- compete、competition、competitively、competitiveness、contest、rival
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- 関
- antagonist、blocking agent、inhibitor
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- 関
- neuromuscular blocking agent、neuromuscular blocking drug