- 血球貪食症候群 hemophagocytic syndrome
- ハンタウイルス肺症候群 hantavirus pulmonary syndrome
- 肝肺症候群 hepatopulmonary syndrome
- Heart Protection Study
- ヘルマンスキー・プドラック症候群 Hermansky-Pudlak syndrome
WordNet
- the 8th letter of the Roman alphabet (同)h
PrepTutorEJDIC
- hydrogenの化学記号
- 鉛筆の硬度 / 《俗》heroin
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/07 18:52:40」(JST)
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- 1. 肝肺症候群：有病割合、原因、臨床症状、および診断 hepatopulmonary syndrome prevalence causes clinical manifestations and diagnosis
- 2. 肝肺症候群：自然経過、治療、および転帰 hepatopulmonary syndrome natural history treatment and outcomes
- 3. 冠動脈疾患または同等の冠動脈リスクを有する患者におけるコレステロール低下に関する
臨床試験 clinical trials of cholesterol lowering in patients with coronary heart disease or coronary risk equivalents - 4. ハンタウイルス心肺症候群 hantavirus cardiopulmonary syndrome
- 5. 侵襲的心臓電気生理学的検査：徐脈性不整脈 invasive cardiac electrophysiology studies bradyarrhythmias
English Journal
- Epidemiology of Hantavirus infections in humans: a comprehensive, global overview.
- Watson DC1, Sargianou M, Papa A, Chra P, Starakis I, Panos G.Author information 1Division of Infectious Diseases, Department of Internal Medicine, Patras University General Hospital , Patras , Greece .AbstractHantaviruses comprise an emerging global threat for public health, affecting about 30,000 humans annually. Infection may lead to Hantavirus pulmonary syndrome (HPS) in the Americas and hemorrhagic fever with renal syndrome (HFRS) in the Europe and Asia. Humans are spillover hosts, acquiring infection primarily through the inhalation of aerosolized excreta from infected rodents and insectivores. Risk factors for infection include involvement in outdoor activities, such as rural- and forest-related activities, peridomestic rodent presence, exposure to potentially infected dust and outdoor military training; prolonged, intimate contact with infected individuals promotes transmission of Andes virus, the only Hantavirus known to be transmitted from human-to-human. The total number of Hantavirus case reports is generally on the rise, as is the number of affected countries. Knowledge of the geographical distribution, regional incidence and associated risk factors of the disease are crucial for clinicians to suspect and diagnose infected individuals early on. Climatic, ecological and environmental changes are related to fluctuations in rodent populations, and subsequently to human epidemics. Thus, prevention may be enhanced by host-reservoir control and human exposure prophylaxis interventions, which likely have led to a dramatic reduction of human cases in China over the past decades; vaccination may also play a role in the future.
- Critical reviews in microbiology.Crit Rev Microbiol.2014 Aug;40(3):261-72. doi: 10.3109/1040841X.2013.783555. Epub 2013 Apr 22.
- Hantaviruses comprise an emerging global threat for public health, affecting about 30,000 humans annually. Infection may lead to Hantavirus pulmonary syndrome (HPS) in the Americas and hemorrhagic fever with renal syndrome (HFRS) in the Europe and Asia. Humans are spillover hosts, acquiring infectio
- PMID 23607444
- Dual amplified and ultrasensitive electrochemical detection of mutant DNA Biomarkers based on nuclease-assisted target recycling and rolling circle amplifications.
- Wang Q1, Yang C1, Xiang Y2, Yuan R1, Chai Y1.Author information 1Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.2Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. Electronic address: yunatswu@swu.edu.cn.AbstractBased on nicking endonuclease (NEase)-assisted target recycling and rolling circle amplification (RCA) for in situ generation of numerous G-quadruplex/hemin complexes, we developed a new, dual amplified and ultrasensitive electrochemical biosensor for mutant human p53 gene. The target mutant DNA hybridizes with the loop portion of a dithiol-modified hairpin probe (HP) self-assembled on a gold sensing electrode and forms nicking site for the NEase, which cleaves the HP and releases the target DNA. The released target DNA again hybridizes with the intact HP and initiates the DNA recycling process with the assistance of the NEase, leading to the cleavage of a large number of the HPs and the generation of numerous primers for RCA. With rationally designed, G-quadruplex complementary sequence-encoded RCA circular template, subsequent RCA results in the formation of long DNA sequences with massive tandem-repeat G-quadruplex sequences, which further associate with hemin and generate significantly amplified current response for highly sensitive DNA detection down to 0.25 fM. The developed method also exhibits high specificity for the target DNA against single-base mismatched sequence. With the ultrahigh sensitivity feature induced by the dual signal amplification, the proposed method can thus offer new opportunities for the detection of trace amounts of DNA.
- Biosensors & bioelectronics.Biosens Bioelectron.2014 May 15;55:266-71. doi: 10.1016/j.bios.2013.12.034. Epub 2013 Dec 21.
- Based on nicking endonuclease (NEase)-assisted target recycling and rolling circle amplification (RCA) for in situ generation of numerous G-quadruplex/hemin complexes, we developed a new, dual amplified and ultrasensitive electrochemical biosensor for mutant human p53 gene. The target mutant DNA hyb
- PMID 24393655
- Using public health scenarios to predict the utility of a national syndromic surveillance programme during the 2012 London Olympic and Paralympic Games.
- Morbey RA1, Elliot AJ1, Charlett A2, Ibbotson S3, Verlander NQ2, Leach S4, Hall I4, Barrass I4, Catchpole M5, McCloskey B6, Said B7, Walsh A7, Pebody R8, Smith GE1.Author information 1Health Protection Agency (HPA), Real-time Syndromic Surveillance Team, Health Protection Services, Birmingham, UK.2HPA, Statistics, Modelling and Economics Department, London, UK.3HPA, West Midlands Regional Director's Office, Birmingham, UK.4HPA, Emergency Response Department, Porton Down, UK.5HPA, Health Protection Services, London, UK.6HPA, London Regional Director's Office, Head, WHO Collaborating Centre on Mass Gatherings and High Consequence, High Visibility Events, London, UK.7HPA, Gastrointestinal, Emerging and Zoonotic Infections Department, HPS Colindale, London, UK.8HPA, Respiratory Diseases Department, HPS Colindale, London, UK.AbstractSUMMARY During 2012 real-time syndromic surveillance formed a key part of the daily public health surveillance for the London Olympic and Paralympic Games. It was vital that these systems were evaluated prior to the Games; in particular what types and scales of incidents could and could not be detected. Different public health scenarios were created covering a range of potential incidents that the Health Protection Agency would require syndromic surveillance to rapidly detect and monitor. For the scenarios considered it is now possible to determine what is likely to be detectable and how incidents are likely to present using the different syndromic systems. Small localized incidents involving food poisoning are most likely to be detected the next day via emergency department surveillance, while a new strain of influenza is more likely to be detected via GP or telephone helpline surveillance, several weeks after the first seed case is introduced.
- Epidemiology and infection.Epidemiol Infect.2014 May;142(5):984-93. doi: 10.1017/S095026881300188X. Epub 2013 Aug 1.
- SUMMARY During 2012 real-time syndromic surveillance formed a key part of the daily public health surveillance for the London Olympic and Paralympic Games. It was vital that these systems were evaluated prior to the Games; in particular what types and scales of incidents could and could not be detec
- PMID 23902949
Japanese Journal
- 感染症による汎血球減少 (特集 汎血球減少症)
- 血液内科 = Hematology 72(6), 800-805, 2016-06
- NAID 40020898904
- 膠原病患者における汎血球減少 (特集 汎血球減少症)
- 血液内科 = Hematology 72(6), 788-794, 2016-06
- NAID 40020898890
- 看護基礎教育におけるシミュレーション教育プログラム導入の試み
- 日本シミュレーション医療教育学会雑誌 = Journal of Japan Association for Simulation-based Education in Healthcare Professionals 4, 54-63, 2016
- NAID 40020895763
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★リンクテーブル★
| リンク元 | 「ハンタウイルス属」「血球貪食症候群」「肝肺症候群」「ハンタウイルス肺症候群」「ヘルマンスキー・プドラック症候群」 |
| 関連記事 | 「HP」「H」 |
「ハンタウイルス属」
- 英
- hantavirus, genus hantavirus
- 関
- ウイルス
- ブニヤウイルス科に属する。
ハンタウイルス属
- ハンタウイルス → 腎症候性出血熱
- 名無しウイルス Sin Nombre virus → ハンタウイルス肺症候群
ハンタウイルス感染症
| HFRS | HPS | |||
| Hantaan | Seoul | Puumala | Sin Nombre | |
| 分布 | アジア | 世界 | 北欧 | 米国 |
| 自然宿主 | アポデムス | ドブネズミ | ヤチネズミ | シカシロアシネズミ |
| 発症部位 | 腎性 | 肺性 | ||
| 発症程度 | 中。重症 | 軽症 | 重症 | |
| 死亡率 | 5-15% | 0.01 | <0.1% | 0.6 |
| 疾患名 | 韓国型出血熱 | 腎症候性出血熱 | nephropathia epidermica | ハンタウイルス肺症候群 |
「血球貪食症候群」
病因
- 参考1 YN.G-67
- 頻度：悪性リンパ腫50%、ウイルス30%、細菌・真菌10%、数%膠原病
- 一次性血球貪食症候群
- 家族性の血球貪食症候群
- 二次性血球貪食症候群
- 悪性リンパ腫
- 感染症：
- ウイルス：EBウイルス、サイトメガロウイルス、パルボウイルス、単純ヘルペスウイルス、水痘・帯状疱疹ウイルス、風疹ウイルス、ヒトヘルペスウイルス8型
- 細菌：ブルセラ属、グラム陰性細菌、結核
- 寄生虫：リーシュマニア症
- 真菌
病態
- 血球を貪食した活性化マクロファージが骨髄、肝臓、脾臓、リンパ節で増殖。
症状
- 発熱、全身倦怠感、汎血球減少(少なくとも2系統)、DIC、肝脾腫、肝不全
検査
- 血算：血球減少
- 血液生化学
- 骨髄塗沫：血球貪食像
治療
- 参考1
- HLH-2004 protocolに基づく治療を
- デキサメタゾン、エトポシド、メトトレキサート
- 造血細胞移植
診断基準
参考
- 1. [charged] 血球貪食性リンパ組織球症（HLH） - uptodate [1]
- 2. wiki ja
- 3. 血球貪食症候群 - 難病情報センター
国試
「肝肺症候群」
- 明らかな心肺疾患がないにもかかわらず、肝疾患・門脈亢進症の患者において、肺内血管拡張をきたし低酸素血症を呈する病態。治療は確立されておらず、重症例を除いて肝移植が唯一有効。(SSUR.594)
参考
- PMID 18509123
「ハンタウイルス肺症候群」
- 新興感染症
- ハンタウイルス属Sin Nombre virusによる感染症
- 1993年に米国のNew Mexicoに出現。
- 急性肺疾患
- 死亡率65％に達する
「ヘルマンスキー・プドラック症候群」
- 英
- Hermansky-Pudlak syndrome、HPS
- 同
- 出血型白皮症候群 albinism-hemorrhagic diathesis syndrome
- 関
- Hermansky-Pudlak症候群、ヘルマンスキー・パドラック症候群
「HP」
- Helicobacter pylori
- ハプトグロビン haptoglobin
- 遺伝性膵炎 hereditary pancreatitis
- 過敏性肺臓炎 過敏性肺炎 hypersensitivity pneumonitis
「H」