WordNet

relating to or according to or affecting a symptom or symptoms; "symptomatic relief"; "symptomatic treatment"; "a symptomatic classification of diseases"

PrepTutorEJDIC

徴候となる;(…の)前兆となる,(…を)示す《+of+名》
高血圧[症] / 過度の緊張

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 成人における高血圧緊急症の評価および治療 evaluation and treatment of hypertensive emergencies in adults
2. 成人における高血圧の概要 overview of hypertension in adults
3. 高血圧緊急症の治療に用いる薬物 drugs used for the treatment of hypertensive emergencies
4. 高血圧：誰が治療が必要か？ hypertension who should be treated
5. 急性および慢性腎臓病における高血圧の概要 overview of hypertension in acute and chronic kidney disease

English Journal

The role of cystatin C as a biomarker for prognosis in pulmonary arterial hypertension due to congenital heart disease.

Blok IM1, van Riel AC1, Schuuring MJ2, de Bruin-Bon RH2, van Dijk AP3, Hoendermis ES4, Zwinderman AH2, Mulder BJ1, Bouma BJ5.
International journal of cardiology.Int J Cardiol.2016 Apr 15;209:242-7. doi: 10.1016/j.ijcard.2016.02.003. Epub 2016 Feb 6.
BACKGROUND: Adults with pulmonary arterial hypertension due to congenital heart disease (PAH-CHD) have a poor prognosis. Identifying patients with a high risk for clinical events and death is important because their prognosis can be improved by intensifying their treatment. Cystatin C, a novel cardi
PMID 26897077

Magnetic resonance imaging biomarkers indicate a central venous hypertension syndrome in patients with symptomatic pineal cysts.

Eide PK1, Pripp AH2, Ringstad GA3.
Journal of the neurological sciences.J Neurol Sci.2016 Apr 15;363:207-16. doi: 10.1016/j.jns.2016.02.038. Epub 2016 Feb 17.
BACKGROUND: While most pineal cysts (PCs) are asymptomatic, some PCs are accompanied with symptoms of variable severity. We suggested that symptom severity in symptomatic patients with non-hydrocephalic PCs relates to venous compression causing central venous hypertension. This study explored whethe
PMID 27000252

Hepatitis E Virus-Induced Cryoglobulinemic Glomerulonephritis in a Nonimmunocompromised Person.

Guinault D1, Ribes D1, Delas A2, Milongo D3, Abravanel F4, Puissant-Lubrano B5, Izopet J4, Kamar N6.
American journal of kidney diseases : the official journal of the National Kidney Foundation.Am J Kidney Dis.2016 Apr;67(4):660-3. doi: 10.1053/j.ajkd.2015.10.022. Epub 2015 Dec 10.
Hepatitis E virus (HEV)-related kidney disease and symptomatic cryoglobulinemia have been observed in solid-organ transplant recipients. However, HEV RNA in the cryoprecipitate has not yet been assessed. We report what to our knowledge is the first documented case of autochthonous HEV-induced cryogl
PMID 26682764

Japanese Journal

Elevated Lipoprotein(a) has Incremental Prognostic Value in Type 2 Diabetic Patients with Symptomatic Coronary Artery Disease

, , , , , , , , , , , , ,
Journal of Atherosclerosis and Thrombosis 22(5), 527-534, 2015
… Therefore, we sought to evaluate the prognostic value of elevated lipoprotein(a) [Lp(a)] in type 2 diabetic patients with symptomatic coronary artery disease (CAD).Methods: A total of 1494 diabetic patients with CAD (62.3% men, mean age: 63.5±10.3 years) were enrolled. … A survival probability plot according to the Lp(a) tertile revealed that an elevated Lp(a) level was associated with a worse prognosis (p=0.008), after adjusting for age, gender, hypertension, hyperlipidemia, smoking and the extent of CAD. …
NAID 130005071051

Endovascular Treatment of Iliac Vein Compression (May-Thurner) Syndrome: Angioplasty and Stenting with or without Manual Aspiration Thrombectomy and Catheter-directed Thrombolysis

, , , , , ,
Annals of Vascular Diseases advpub(0), 2015
… Eighteen patients presented with deep vein thrombosis (DVT) and five with symptoms associated with chronic venous hypertension (CVH). … Upon follow-up, complete symptomatic regression was observed in 19 of the 23 patients (82.6%). …
NAID 130004949165

Platelet-Derived Growth Factor Receptor-Tyrosine Kinase Inhibitor, Imatinib, Is Effective for Treating Pulmonary Hypertension Induced by Pulmonary Tumor Thrombotic Microangiopathy

, , , , , , , , , , , , , ,
International Heart Journal advpub(0), 2015
… Pulmonary hypertension (PH) induced by pulmonary tumor thrombotic microangiopathy (PTTM) can be fatal because its rapid progression confounds diagnosis, and it is difficult to control with therapy. … Here we describe a woman with symptomatic PTTM-PH accompanying gastric cancer that was suspected from perfusion scintigraphy. … Thus, PTTM-PH was successfully controlled using a combination of imatinib, drugs to treat pulmonary arterial hypertension, and cancer management. …
NAID 130004941343

「二次性高血圧」

　　[★]

英: secondary hypertension
同: 症候性高血圧 symptomatic hypertension
関: 高血圧、本態性高血圧

病因

腎血管性
内分泌性

代謝異常

リドル症候群？
11β-水酸化酵素欠損症 AME症候群：11β-ヒドロキシステロイド脱水素酵素(11β-HSD)の欠損
17α-水酸化酵素欠損症

過剰産生

デオキシコルチコステロン産生腫瘍/DOC産生腫瘍

薬剤性

グリチルリチンによる偽アルドステロン症

妊娠誘発性

二次性高血圧を連想する症状

腎実質性高血圧：蛋白尿、血尿、腎機能低下、腎疾患既往
腎血管性高血圧：若年者、急激な血圧上昇、腹部血管雑音、低カリウム血症
原発性アルドステロン症：四肢脱力、夜間多尿、低カリウム血症
クッシング症候群：中心性肥満、満月様顔貌、皮膚線状、高血糖
褐色細胞腫：発作性・動揺性高血圧、動悸・発汗、頭痛、神経線維腫
甲状腺機能低下症：徐脈、浮腫、活動性減少、脂質・CK・LDH上昇
甲状腺機能亢進症：頻脈、発汗、体重減少、コレステロール低値

二次性高血圧を疑わせる臨床所見

JSH2014 第13章二次性高血圧

原因疾患	示唆する所見	鑑別に必要な検査
二次性高血圧一般	重症高血圧、治療抵抗性高血圧、急激な高血圧発症、若年発症の高血圧
腎血管性高血圧	RA系阻害薬投与後の急激な腎機能悪化、腎サイズの左右差、低K血症、腹部血管雑音	腎動脈超音波、腹部CTA、腹部MRA、レノグラム、PRA、PAC
腎実質性高血圧	血清Cr上昇、蛋白尿、血尿、腎疾患の既往	血清免疫学的検査、腹部CT、超音波、腎生検
原発性アルドステロン症	低K血症、副腎偶発腫瘍	PRA、PAC、負荷試験、副腎CT、副腎静脈採血
睡眠時無呼吸症候群	いびき、肥満、昼間の眠気、早朝・夜間高血圧	睡眠ポリグラフィー
褐色細胞腫	発作性・動揺性高血圧、動悸、頭痛、発汗	血液・尿カテコールアミンおよびカテコールアミン代謝産物、腹部超音波・CT、MIBGシンテグラフィー
クッシング症候群	中心性肥満、満月様顔貌、皮膚線条、高血糖	コルチゾール、ACTH、腹部CT、頭部MRI、デキサメサゾン抑制試験
サブクリニカルクッシング症候群	副腎偶発腫瘍	コルチゾール、ACTH、腹部CT、デキサメサゾン抑制試験
薬物誘発性高血圧	薬物使用歴、低K血症	薬物使用歴の確認
大動脈縮窄症	血圧上下肢差、血管雑音	胸腹部CT、MRI・MRA、血管造影
甲状腺機能低下症	徐脈、浮腫、活動性減少、脂質・CPK・LDH高値	甲状腺ホルモン、TSH、自己抗体、甲状腺超音波
甲状腺機能亢進症	頻脈、発汗、体重減少、コレステロール低値	甲状腺ホルモン、TSH、自己抗体、甲状腺超音波
副甲状腺機能亢進症	高Ca血症	副甲状腺ホルモン
脳幹部血管圧迫	顔面けいれん、三叉神経痛	頭部MRI・MRA