hemolytic anemia

specific types


  1. relating to or involving or causing hemolysis; "hemolytic anemia" (同)haemolytic
  2. a deficiency of red blood cells (同)anaemia
  3. a lack of vitality (同)anaemia
  4. genus of terrestrial or lithophytic ferns having pinnatifid fronds; chiefly of tropical America (同)genus Anemia

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/11/05 04:11:02」(JST)

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English Journal

  • Management of immune-mediated cytopenias in pregnancy.
  • Piatek CI1, El-Hemaidi I2, Feinstein DI1, Liebman HA1, Akhtari M3.
  • Autoimmunity reviews.Autoimmun Rev.2015 Sep;14(9):806-11. doi: 10.1016/j.autrev.2015.05.003. Epub 2015 May 13.
  • Immune-mediated cytopenias are a well-described complication of pregnancy. Appropriate recognition and treatment are important in order to limit maternal and fetal morbidity and mortality. First line treatment options are fairly well-established for these entities. Refractory disease may be difficul
  • PMID 25981747
  • Transiently Pink-Tinged Serum in a Patient With Multiple Myeloma and Anemia Undergoing Lenalidomide Treatment.
  • Wedel W1, Sofronescu AG2.
  • American journal of clinical pathology.Am J Clin Pathol.2015 Aug;144(2):329-32. doi: 10.1309/AJCP4RB3YNAWZPZN.
  • OBJECTIVES: While in vitro hemolysis is a preanalytical interferent, in vivo hemolysis is a pathologic process requiring investigation. We present a case of an anemic patient with multiple myeloma undergoing chemotherapy with lenalidomide who had multiple serum samples drawn before and after chemoth
  • PMID 26185319
  • Immunogenicity, Safety, and Tolerability of 13-Valent Pneumococcal Conjugate Vaccine Followed by 23-Valent Pneumococcal Polysaccharide Vaccine in Recipients of Allogeneic Hematopoietic Stem Cell Transplant Aged ≥2 Years: An Open-Label Study.
  • Cordonnier C1, Ljungman P2, Juergens C3, Maertens J4, Selleslag D5, Sundaraiyer V6, Giardina PC7, Clarke K8, Gruber WC7, Scott DA7, Schmoele-Thoma B3; 3003 Study Group.
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.Clin Infect Dis.2015 Aug 1;61(3):313-23. doi: 10.1093/cid/civ287. Epub 2015 Apr 13.
  • BACKGROUND: Life-threatening Streptococcus pneumoniae infections often occur after hematopoietic stem cell transplant (HSCT); vaccination is important for prevention.METHODS: In an open-label study, patients (n = 251) 3-6 months after allogeneic HSCT received 3 doses of 13-valent pneumococcal conjug
  • PMID 25870329

Japanese Journal

  • Hemolytic Anemia soon after Replacement of Ascending Aorta for acute Aortic Dissection
  • Shibasaki Ikuko,Fukuda Hirotsugu,Yamada Yasuyuki,Kuwata Toshiyuki,Ogawa Hironaga,Tsuchiya Go,Hori Takayuki,Takei Yusuke,Kato Takashi
  • Dokkyo journal of medical sciences 42(1), 37-41, 2015-03-25
  • … A 61-year-old female underwent replacement of the ascending aorta for Type A aortic dissection, then gradually developed severe hemolytic anemia over 1 month. … Here, we report a rare case of hemolytic anemia at the site of an inverted felt strip that occurred after replacement of the ascending aorta. …
  • NAID 110009909846
  • Hereditary Spherocytosis in a Middle-aged Man Complicated with Common Bile Duct Stones
  • Sawahara Hiroaki,Iwamuro Masaya,Harada Ryo,Yoshioka Masao,Niguma Takefumi,Mimura Tetsushige,Yamamoto Kazuhide
  • Internal Medicine 54(12), 1509-1512, 2015
  • … Hereditary spherocytosis is the most common form of hemolytic anemia and is characterized by spherical, osmotically fragile erythrocytes that are selectively trapped by the spleen. … He had no anemia and was asymptomatic with mild splenomegaly. … In the differential diagnosis of these symptoms, the possibility of hereditary spherocytosis should be considered, even in patients who are middle-aged and lack anemia. …
  • NAID 130005075955
  • Eculizumab導入後に全身麻酔下での整形外科手術を安全に施行できた発作性夜間ヘモグロビン尿症
  • 筒井 深雪,後藤 明彦,安田 肇 [他],小野 英里子,田中 勝,小松 則夫
  • 臨床血液 56(4), 423-427, 2015
  • 発作性夜間ヘモグロビン尿症(paroxysmal nocturnal hemoglobinuria, PNH)は造血幹細胞の異常により溶血,血栓症,造血不全を呈する希な疾患である。PNHでは感染,妊娠などのストレスを契機として溶血発作を生じることが知られているが,外科手術も強い補体活性化を引き起こし,溶血発作の重要なリスク因子である。また,術後血栓症のリスクも高い。ヒト化抗C5抗体eculizum …
  • NAID 130005069849

Related Links

Hemolytic anemia (or haemolytic anaemia) is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels ( intravascular hemolysis) or elsewhere in the human body (extravascular).

リンク元溶血性貧血」「microangiopathic anemia」「hemolytic jaundice」「haemolytic anaemia
拡張検索acquired hemolytic anemia」「congenital hemolytic anemia」「microangiopathic hemolytic anemia



hemolytic anemia
溶血性黄疸 hemolytic jaundice
溶血の種類 機序 脾腫 ヘモグロビン尿
血管外溶血 Mφで貪食される 球状赤血球症 HS
自己免疫性溶血性貧血 AIHA (温式)
血管内溶血 血管内で溶血 自己免疫性溶血性貧血 AIHA (冷式)
発作性夜間ヘモグロビン尿症 PNH


  • 赤血球寿命が種々の原因により短縮することに伴う貧血の総称。


  • 赤血球が何らかの原因により破壊され、骨髄の代償能力を超えて赤血球が減少することにより貧血を呈する。 → 溶血が存在するが貧血ではない状態がある。
  • 溶血の原因
  • 先天性疾患
  • 後天性疾患
  • 自己抗体による溶血



  • 1. ヘモグロビンの異常
  • 2. 膜-細胞骨格複合体の異常
  • 3. 代謝経路


  • 先天性
  • 家族性溶血尿毒症 familial hemolytic uremic syndrome
  • 後天性


  • 貧血、無胆汁色素尿性または溶血性黄疸、脾腫


  • [charged]Extrinsic nonimmune hemolytic anemia due to mechanical damage: Fragmentation hemolysis and hypersplenism - uptodate

microangiopathic anemia」



acquired hemolytic anemiahemolytic anemiahemolytic jaundice

hemolytic jaundice」



acquired hemolytic anemiahemolytic anemiamicroangiopathic anemia

haemolytic anaemia」



hemolytic anemia

acquired hemolytic anemia」



hemolytic anemiahemolytic jaundicemicroangiopathic anemia

congenital hemolytic anemia」



hereditary hemolytic anemia

microangiopathic hemolytic anemia」

  [★] 微小血管障害性溶血性貧血 MHA



  • adj.
  • 溶血性の、溶血の