自己免疫性溶血性貧血
WordNet
- relating to or involving or causing hemolysis; "hemolytic anemia" (同)haemolytic
- a deficiency of red blood cells (同)anaemia
- a lack of vitality (同)anaemia
- of or relating to the immune response of the body against substance normally present in the body
UpToDate Contents
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English Journal
- Serpentine supravenous hyperpigmentation secondary to superficial venous thrombosis in autoimmune hemolytic anemia.
- Avarbock AB, Gill KZ, Lauren CT, Chong DH, Silvers DN, Grossman ME.SourceDepartment of Dermatology, Columbia-Presbyterian Medical Center, New York, NY, USA. aa2902@columbia.edu.
- International journal of dermatology.Int J Dermatol.2013 Jan 20. doi: 10.1111/j.1365-4632.2012.05721.x. [Epub ahead of print]
- PMID 23330569
- Simultaneous romiplostin, eltrombopag, and prednisone were successful in severe thrombocytopenia of Evans syndrome refractory to hydrocortisone, splenectomy, intravenous IgG, and rituximab.
- Ruiz-Arguelles GJ, Ruiz-Delgado GJ, Velázquez-Sánchez-de-Cima S, Zamora-Ortiz G.AbstractA 58-year-old woman presented with rheumatoid arthritis-associated Evans syndrome (simultaneous autoimmune hemolytic anemia and autoimmune thrombocytopenic purpura); she was treated unsuccesfully with steroids, romiplostin, rituximab, immunoglobulin G, and splenectomy. The platelet count responded to the combined use of prednisone, eltrombopag, and romiplostin. It may be more reasonable to use combined treatments than sequential monotherapies.
- Hematology (Amsterdam, Netherlands).Hematology.2013 Jan 8. [Epub ahead of print]
- A 58-year-old woman presented with rheumatoid arthritis-associated Evans syndrome (simultaneous autoimmune hemolytic anemia and autoimmune thrombocytopenic purpura); she was treated unsuccesfully with steroids, romiplostin, rituximab, immunoglobulin G, and splenectomy. The platelet count responded t
- PMID 23321502
- MicroRNAs expression in chronic lymphocytic leukemia developing autoimmune hemolytic anemia.
- Ferrer G, Navarro A, Hodgson K, Aymerich M, Pereira A, Baumann T, Monzo M, Moreno C, Montserrat E.AbstractABSTRACT Chronic lymphocytic leukemia (CLL) is frequently associated with autoimmune hemolytic anemia (AIHA). However, the mechanisms governing the association between CLL and AIHA are poorly understood. miRNAS have been associated with different clinico-biological forms of CLL and are also known to play a substantial role in autoimmunity. However, there are no studies correlating miRNAs expression with the likelihood that patients with CLL will develop AIHA. In this study, we found that malignant B- cells from patients with CLL subsequently developing AIHA present nine downregulated (i.e., miR-19a, miR-20a, miR-29c miR-146b-5p, miR-186, miR-223 miR-324-3p, miR-484 and miR-660) miRNAs. Interestingly, two of these miRNAs (i.e., miR-20a and miR-146b-5p) are involved in autoimmune phenomena, and one (i.e., miR-146b-5p) in both autoimmunity and CLL. Furthermore, we demonstrate that miR-146b-5p modulates CD80, a molecule associated with the B-T-cell synapse and in restoring the antigen presenting capacity of CLL cells.
- Leukemia & lymphoma.Leuk Lymphoma.2013 Jan 4. [Epub ahead of print]
- ABSTRACT Chronic lymphocytic leukemia (CLL) is frequently associated with autoimmune hemolytic anemia (AIHA). However, the mechanisms governing the association between CLL and AIHA are poorly understood. miRNAS have been associated with different clinico-biological forms of CLL and are also known
- PMID 23286334
Japanese Journal
- 赤芽球ろうから自己免疫性溶血性貧血を伴った全身性エリテマトーデスに移行した1例
- 原田 直樹,長沢 浩平,岡村 孝,仁保 喜之
- 日本臨床免疫学会会誌 13(3), 286-291, 1990
- 赤芽球ろうから自己免疫性溶血性貧血を伴った全身性エリテマトーデスに移行した1例を報告する.症例は27歳女性で発熱,関節痛,筋肉痛にて入院. Hb 6.6g/dlと貧血を認め,尿ウロビリノーゲン(3+),直接クームステスト陽性,ハプトグロビン<10mg/dlより自己免疫性溶血性貧血(AIHA)と診断.また,多関節炎,白血球減少, LE細胞陽性,抗DNA抗体高値, ANF強陽性より全身性エリテマ …
- NAID 130000851279
- 自己免疫性溶血性貧血における自己抗体の認識抗原の生化学的構造の解明と免疫ネットワーク説
Related Links
- Summary Description Autoimmune hemolytic anemia (AIHA) is caused by autoantibody-induced hemolysis (the premature destruction of circulating red blood cells); usually idiopathic, it is also associated with infection ...
- autoimmune hemolytic anemia AIHA; a general term covering a large group of anemias involving autoantibodies against red cell antigens; they may be idiopathic or may have any of a number of causes, including autoimmune ...
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- 関
- haemolysis、haemolytic、hemolysis、hemolyze