急性炎症性多発ニューロパチー、急性炎症性多発ニューロパシー
WordNet
- of critical importance and consequence; "an acute (or critical) lack of research funds"
- having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
- extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
- having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
- of an angle; less than 90 degrees
- characterized or caused by inflammation; "an inflammatory process"; "an inflammatory response"
PrepTutorEJDIC
- (先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
- 炎症を起こす,炎症性の / 憤激させる,扇動的な
UpToDate Contents
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- 1. 成人におけるギラン・バレー症候群の臨床的特徴および診断 clinical features and diagnosis of guillain barre syndrome in adults
- 2. 多発性神経障害の概要 overview of polyneuropathy
- 3. 成人におけるギラン・バレー症候群の治療および予後 treatment and prognosis of guillain barre syndrome in adults
- 4. 小児における後天性末梢性ニューロパチーの概要 overview of acquired peripheral neuropathies in children
- 5. 慢性炎症性脱髄性多発神経炎：病因、臨床的特徴、および診断 chronic inflammatory demyelinating polyneuropathy etiology clinical features and diagnosis
English Journal
- A cloudy story: Guillain-Barré syndrome concealed by a spontaneous intracerebral haemorrhage.
- Mantero V, De Toni Franceschini L, Abate L, Villa F, Patruno A, Jann S, Citerio G.SourceDepartment of Neurosciences, Niguarda Ca' Granda Hospital, Milano, Italy. Electronic address: vittorio.mantero@ospedaleniguarda.it.
- Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology.Clin Neurophysiol.2013 May;124(5):1037-8. doi: 10.1016/j.clinph.2012.09.020. Epub 2012 Oct 18.
- PMID 23084662
- Acute myelopathy with normal imaging.
- Holland NR.Source1Neuroscience Institute, Monmouth Medical Center, Long Branch, NJ, USA.
- Journal of child neurology.J Child Neurol.2013 May;28(5):648-50. doi: 10.1177/0883073812448438. Epub 2012 Jun 29.
- A 17-year-old girl presented with rapidly progressive quadriparesis and ventilatory failure. The clinical findings indicated a spinal level, but the diagnosis of myelopathy was not supported by her initial spinal imaging and cerebrospinal fluid studies. She had completed treatment for Guillain-Barr�
- PMID 22752484
- Bickerstaff brainstem encephalitis and Fisher syndrome: anti-GQ1b antibody syndrome.
- Shahrizaila N, Yuki N.SourceDepartment of Medicine, Unit 09-01, National University of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore; yuki.research@gmail.com.
- Journal of neurology, neurosurgery, and psychiatry.J Neurol Neurosurg Psychiatry.2013 May;84(5):576-83. doi: 10.1136/jnnp-2012-302824. Epub 2012 Sep 15.
- In the 1950s, Bickerstaff and Fisher independently described cases with a unique presentation of ophthalmoplegia and ataxia. The neurological features were typically preceded by an antecedent infection and the majority of patients made a spontaneous recovery. In the cases with Bickerstaff brainstem
- PMID 22984203
Japanese Journal
- Acute Transverse Myelitis and Acute Motor Axonal Neuropathy Developed after Vaccinations against Seasonal and 2009 A/H1N1 Influenza
- Sato Nozomu,Watanabe Kosuke,Ohta Kiyobumi,Tanaka Hiroaki
- Internal Medicine 50(5), 503-507, 2011
- … Acute transverse myelitis (ATM) has been described as an uncommon complication of vaccinations and is rarely accompanied by inflammatory peripheral neuropathy. … We report a case of a 77-year-old woman who developed ATM and acute motor axonal neuropathy (AMAN) following vaccinations against seasonal and 2009 A/H1N1 influenza. … MR imaging showed a longitudinally-extensive spinal cord lesion, and nerve conduction study revealed motor axonal polyneuropathy. …
- NAID 130000649869
- Abnormal Median Normal Sural Sensory Response in a Patient with an Oropharyngeal Variant of Guillain-Barre Syndrome
- Yamazaki Yuu,Sugiura Tomohito,Kurokawa Katsumi
- Internal Medicine 49(5), 519-520, 2010
- NAID 130000251712
Related Links
- 6 Feb 2012 ... Acute inflammatory demyelinating polyneuropathy (AIDP) is an autoimmune process that is characterized by progressive areflexic weakness and mild sensory changes. Sensory symptoms often precede motor weakness.
Related Pictures
★リンクテーブル★
| リンク元 | 「ギラン・バレー症候群」「AIDP」「acute inflammatory demyelinating polyradiculoneuropathy」「急性炎症性多発ニューロパチー」 |
| 関連記事 | 「acute」「inflammatory」 |
「ギラン・バレー症候群」
- 英
- Guillain-Barré syndrome Guillain-Barre syndrome GBS
- 同
- (国試)Guillain-Barre症候群
- 急性炎症性脱髄性多発神経根ニューロパチー acute inflammatory demyelinating polyradiculoneuropathy AIDP
- 感染性多発神経炎 infective polyneuritis infectious polyneuritis、急性炎症性多発ニューロパシー acute inflammatory polyneuropathy
- 関
- 免疫介在性ニューロパチー
病型
- SPE.645
- 急性多発性神経炎：原因不明のもの
- ギラン・バレー症候群：経過中に蛋白細胞解離が見られたもの
- フィッシャー症候群：抗GQ1b-ガングリオシド抗体が出現しているもの
症状
- 知覚異常：(初発)腰痛、手足のしびれ感。感覚障害は軽度にとどまる
- 運動神経：下肢末梢から左右対称性、上行性の弛緩麻痺。腱反射消失
- 自律神経：自律神経の障害による症状(不整脈、洞性頻脈、血圧の変動、発汗異常)が見られることがある。
検査
- 血液
- 血清抗ガングリオシド抗体：陽性
- 抗原：GM1、GQ1b(→Fisher症候群と関連)、GD1a、GalNAc-GD1a、ガラクトセレブロシド
- 脳脊髄液検査
- 蛋白細胞解離。発症から1週間後の患者の80-90%の患者で見られる。近位神経根のレベルで血液神経関門の透過性が亢進したことによるのかもしれない(increased permeability of the blood-nerve-barrier at the level of the proximal nerve roots)。(参考1)
- 末梢神経伝導検査：伝導速度低下
治療
- 対症療法
- 呼吸管理
- 血漿交換
- 免疫吸着療法(プラスマフェレーシス)：侵襲の大きさから大量ガンマグロブリン静注療法が行われることが多いらしい。
- 大量ガンマグロブリン静注療法(高ガンマグロブリン大量静注法)
- ステロイド単独投与の有効性は否定されている。
予後
- 予後良好：2週間程度で極期に達し徐々に回復する。しかしながら約5%の例で死亡、約10%の例では重篤な機能障害を残す。(IMD)
関連疾患
参考
- 1. [charged] Clinical features and diagnosis of Guillain-Barré syndrome in adults - uptodate [1]
- 2. [charged] Treatment and prognosis of Guillain-Barré syndrome in adults - uptodate [2]
国試
「AIDP」
[★] 急性炎症性脱髄性多発ニューロパチー
- 関
- acute inflammatory demyelinating polyradiculoneuropathy、acute inflammatory polyneuropathy、Guillain-Barre syndrome
「acute inflammatory demyelinating polyradiculoneuropathy」
急性炎症性脱髄性多発ニューロパチー
「急性炎症性多発ニューロパチー」
- 英
- acute inflammatory polyneuropathy
- 関
- 急性炎症性多発ニューロパシー
「acute」
- adj.
- (疾患)急性の、急性型の、急性的な。(形状が)鋭い、鋭角の。(感覚、才知などが)鋭い。明敏な、鋭い眼識のある。
「inflammatory」
- adj.
- 炎症性の、炎症の、起炎性の