辺縁帯B細胞リンパ腫
- 関
- lymphoma of mucosa-associated lymphoid tissue、MALT lymphoma、mucosa-associated lymphoid tissue lymphoma
WordNet
- regulate housing in; of certain areas of towns (同)district
- any of the regions of the surface of the Earth loosely divided according to latitude or longitude (同)geographical zone
- (anatomy) any encircling or beltlike structure (同)zona
- a locally circumscribed place characterized by some distinctive features
- an area or region distinguished from adjacent parts by a distinctive feature or characteristic
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- the boundary line or the area immediately inside the boundary (同)border, perimeter
- the amount of collateral a customer deposits with a broker when borrowing from the broker to buy securities (同)security deposit
- an amount beyond the minimum necessary; "the margin of victory"
- the blank space that surrounds the text on a page; "he jotted a note in the margin"
- the 2nd letter of the Roman alphabet (同)b
- the blood group whose red cells carry the B antigen (同)type_B, group B
- producing at a rate that barely covers production costs; "marginal industries"
PrepTutorEJDIC
- (何らかの目的・特徴などによって他の地域と区別された)『地帯』,地域,地区(belt, area) / (気候によって地球を大別した)帯(たい) / 《米》(交通・郵便などの)同一料金区域;(郵便番号で分けた)郵便区 / (環状の)ベルト,輪,帯 / …‘を'地帯(地区)に分ける / (…の目的に)〈地域〉‘を'区画規制する《+名+as(for)+名》 / …‘を'帯で巻く,‘に'帯印をつける
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
- 『へり』,『縁』,端(edge) / (ページの)『余白』,欄外 / (可能の)限界,限度 / (空間・時間・経費・活動などの)余裕,余地 / 利ざや,マージン,販売利益
- 縁の,へりの / 限界の,ぎりぎりの,かろうじて要件を満たす / 《名詞の前にのみ用いて》余白に書いた,欄外の / かろうじて帳じりの合う,限界収益点の / 取るに足りない,小さな
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/02/08 13:58:27」(JST)
[Wiki en表示]
Marginal zone B-cell lymphoma |
Classification and external resources |
ICD-9 |
200.3 |
ICD-O: |
M9699/3 |
MeSH |
D018442 |
Marginal zone B-cell lymphoma is a type of B-cell lymphoma presenting primarily in the marginal zone.
There are three types:[1][2]
- Splenic marginal zone lymphoma
- Extranodal marginal zone B cell lymphoma (MALT lymphoma, or "mucosa-associated lymphoid tissue")
- Nodal marginal zone B cell lymphoma (NMZL)
All three are CD5 and CD10 negative
See also
- Primary cutaneous marginal zone lymphoma
References
- ^ Berger F, Felman P, Thieblemont C, et al. (March 2000). "Non-MALT marginal zone B-cell lymphomas: a description of clinical presentation and outcome in 124 patients". Blood 95 (6): 1950–6. PMID 10706860. http://www.bloodjournal.org/cgi/pmidlookup?view=long&pmid=10706860.
- ^ Thieblemont C (2005). "Clinical presentation and management of marginal zone lymphomas". Hematology Am Soc Hematol Educ Program 2005: 307–13. doi:10.1182/asheducation-2005.1.307. PMID 16304396. http://www.asheducationbook.org/cgi/pmidlookup?view=long&pmid=16304396.
Hematological malignancy/leukemia histology (ICD-O 9590–9989, C81–C96, 200–208)
Lymphoid/Lymphoproliferative, Lymphomas/Lymphoid leukemias (9590–9739, 9800–9839)
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B cell
(lymphoma,
leukemia)
(most CD19
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By development/
marker
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TdT+
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- ALL (Precursor B acute lymphoblastic leukemia/lymphoma)
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CD5+
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mantle zone (Mantle cell)
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CD22+
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- Prolymphocytic
- CD11c+ (Hairy cell leukemia)
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CD79a+
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- germinal center/follicular B cell (Follicular
- Burkitt's
- GCB DLBCL
- Primary cutaneous follicular lymphoma)
marginal zone/marginal-zone B cell (Splenic marginal zone
- MALT
- Nodal marginal zone
- Primary cutaneous marginal zone lymphoma)
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RS (CD15+, CD30+)
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- Classic Hodgkin's lymphoma (Nodular sclerosis)
- CD20+ (Nodular lymphocyte predominant Hodgkin's lymphoma)
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PCDs/PP
(CD38+/CD138+)
|
- see immunoproliferative immunoglobulin disorders
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|
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By infection
|
- KSHV (Primary effusion)
- EBV (Lymphomatoid granulomatosis
- Post-transplant lymphoproliferative disorder)
- HIV (AIDS-related lymphoma)
- Helicobacter pylori (MALT lymphoma)
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|
Cutaneous
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- Diffuse large B-cell lymphoma
- Intravascular large B-cell lymphoma
- Primary cutaneous marginal zone lymphoma
- Primary cutaneous immunocytoma
- Plasmacytoma
- Plasmacytosis
- Primary cutaneous follicular lymphoma
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T/NK
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T cell
(lymphoma,
leukemia)
(most CD3
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By development/
marker
|
- TdT+: ALL (Precursor T acute lymphoblastic leukemia/lymphoma)
- prolymphocyte (Prolymphocytic)
- CD30+ (Anaplastic large-cell lymphoma
- Lymphomatoid papulosis type A)
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Cutaneous
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MF+variants
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- indolent: Mycosis fungoides
- Pagetoid reticulosis
- Granulomatous slack skin
aggressive: Sézary's disease
- Adult T-cell leukemia/lymphoma
|
|
Non-MF
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- CD30-: Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma
- Pleomorphic T-cell lymphoma
- Lymphomatoid papulosis type B
CD30+: CD30+ cutaneous T-cell lymphoma
- Secondary cutaneous CD30+ large cell lymphoma
- Lymphomatoid papulosis type A
|
|
|
Other peripheral
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- Hepatosplenic
- Angioimmunoblastic
- Enteropathy-associated T-cell lymphoma
- Peripheral T-cell lymphoma-Not-Otherwise-Specified (Lennert lymphoma)
- Subcutaneous T-cell lymphoma
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By infection
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- HTLV-1 (Adult T-cell leukemia/lymphoma)
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|
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NK cell/
(most CD56)
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- Aggressive NK-cell leukemia
- Blastic NK cell lymphoma
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T or NK
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- EBV (Extranodal NK-T-cell lymphoma/Angiocentric lymphoma)
- Large granular lymphocytic leukemia
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Lymphoid+myeloid
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- Acute biphenotypic leukaemia
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Lymphocytosis
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- Lymphoproliferative disorders (X-linked lymphoproliferative disease
- Autoimmune lymphoproliferative syndrome)
- Leukemoid reaction
- Diffuse infiltrative lymphocytosis syndrome
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|
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Cutaneous lymphoid hyperplasia |
- Cutaneous lymphoid hyperplasia with bandlike and perivascular patterns
- Cutaneous lymphoid hyperplasia with nodular pattern
- Jessner lymphocytic infiltrate of the skin
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cell/phys/auag/auab/comp, igrc
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UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Primary cutaneous B-cell lymphomas: recent advances in diagnosis and management.
- Sokol L, Naghashpour M, Glass LF.SourceDepartment of Malignant Hematology, Moffitt Cancer Center, Tampa, FL 33612, USA. Lubomir.Sokol@moffitt.org.
- Cancer control : journal of the Moffitt Cancer Center.Cancer Control.2012 Jul;19(3):236-44.
- BACKGROUND: Primary cutaneous B-cell lymphoma (PCBCL) is a heterogeneous group of rare clonal B-cell lymphoproliferative disorders with distinct clinicopathologic features from more common nodal B-cell lymphomas.METHODS: We performed a systematic review of the relevant literature in the MEDLINE data
- PMID 22710899
- Non-Hodgkin lymphoma in Chile: a review of 207 consecutive adult cases by a panel of five expert hematopathologists.
- Cabrera ME, Martinez V, Nathwani BN, Muller-Hermelink HK, Diebold J, Maclennan KA, Armitage J, Weisenburger DD.SourceSección de Hematología, Hospital del Salvador, and Universidad de Chile , Santiago , Chile.
- Leukemia & lymphoma.Leuk Lymphoma.2012 Jul;53(7):1311-7. Epub 2012 Mar 13.
- Abstract The distribution of subtypes of non-Hodgkin lymphoma (NHL) in Latin America is not well known. This Chilean study included 207 consecutive cases of NHL diagnosed at five cancer centers in the capital, Santiago, and one center in Viña del Mar. All cases were reviewed and classified indepe
- PMID 22263570
Japanese Journal
- 鬼頭 勇輔,後藤 尚絵,廣瀬 善信,白橋 幸洋,岩田 尚,高見 剛
- 診断病理 : Japanese journal of diagnostic pathology 28(1), 44-48, 2011-01-31
- NAID 10028288136
- Uveal extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type with concomitant extraocular lesions in a Japanese man
- Tagami Mizuki,Nagai Takayuki,Sekimukai Daisuke [他]
- Japanese journal of ophthalmology 55(5), 585-587, 2011-09
- NAID 40019008573
Related Links
- Surprisingly, the most common differential is the distinction between florid lymphoid hyperplasia associated with H pylori gastritis with lymphoid hyperplasia and incipient marginal zone lymphoma. Morphologic features that favor MALT lymphoma include extensive infiltrates, B-cell lymphocytic infiltrates ...
- 7q31-32 allelic loss is a frequent finding in splenic marginal zone lymphoma. Mateo M, Mollejo M, Villuendas R, Algara P, Sanchez-Beato M, Martnez P, Piris MA The American journal of pathology. 1999 ; 154 (5) : 1583-1589. ...
★リンクテーブル★
[★]
- 英
- chronic lymphocytic leukemia, chronic lymphoid leukemia, CLL
- 関
- 白血病
- first aid step1 2006 p.300,302,303,304,309,310,427,430
概念
- the accumulation of nonproliferating mature-appearing lymphocytes in the blood, marrow, lymph nodes, and spleen.
- monoclonal B lymphocytes.
- CD5+ and CD23+CD5, CD23
- derived from memory B cell.
細胞表面マーカー WCH.2438
臨床像
- HIM.693
|
年齢
|
子供における頻度
|
男性(%)
|
ステージI,II vs III,IV(%)
|
B症状(%)
|
骨髄浸潤(%)
|
消化管浸潤(%)
|
5年生存率(%)
|
B細胞CLL/小リンパ球性リンパ腫
|
65
|
まれ
|
53
|
9 vs 91
|
33
|
72
|
3
|
51
|
疫学
- YN.G-49
- 全白血病の2-3%
- 60歳以上に多い。
- 男女比=2:1
病態
- YN.G-49
- 正常な免疫グロブリンの産生が抑制されるばかりでなく、異常な自己抗体を産生 → 続発性免疫不全症、自己免疫性溶血性貧血
USMLE
参考
- 1. [charged] Epidemiology and clinical manifestations of chronic lymphocytic leukemia - uptodate [1]
- 2. [charged] Pathologic features, diagnosis, and differential diagnosis of chronic lymphocytic leukemia - uptodate [2]
- 3. [charged] Pathophysiology and cytogenetics of chronic lymphocytic leukemia - uptodate [3]
[show details]
[★]
粘膜関連リンパ組織リンパ腫
- 関
- MALT lymphoma、marginal zone B-cell lymphoma、mucosa-associated lymphoid tissue lymphoma
[★]
- 英
- marginal zone B-cell lymphoma
- 関
- モルトリンパ腫、粘膜関連リンパ組織リンパ腫
[★]
濾胞辺緑帯B細胞リンパ腫 marginal zone B-cell lymphoma
[★]
- 英
- marginal zone B-cell lymphoma, MZBCL
[★]
MALT関連節外性辺縁帯B細胞リンパ腫
[★]
MALT関連節外性辺縁帯B細胞リンパ腫
[★]
脾濾胞辺縁帯B細胞リンパ腫
[★]
節性辺縁帯B細胞リンパ腫
[★]
- Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する
[★]
- 関
- additional、brim、edge、extent、extra、limit、limitation、marginally、rim、room
[★]
- 関
- band、cingulum、marginal、zona、zonae、zonal
[★]
- 関
- border、zone
[★]
細胞