WordNet
- malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer (同)leukaemia, leucaemia, cancer of the blood
PrepTutorEJDIC
- 白血病
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/19 06:12:21」(JST)
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This article does not cite any sources. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (January 2010) |
| Prolymphocytic leukemia |
| Classification and external resources |
| ICD-O |
9832-9834 |
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[edit on Wikidata]
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Prolymphocytic leukemia is divided into two types according to the kind of cell involved: B-cell prolymphocytic leukemia and T-cell prolymphocytic leukemia. It is usually classified as a kind of chronic lymphocytic leukemia.
UpToDate Contents
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English Journal
- Epigenetic Drugs Reverse Leukemia Resistance.
- [No authors listed]
- Cancer discovery.Cancer Discov.2015 Sep;5(9):OF3. doi: 10.1158/2159-8290.CD-NB2015-101. Epub 2015 Jul 13.
- T-cell prolymphocytic leukemia initially responds to alemtuzumab but eventually becomes resistant to it. Treatment with epigenetic drugs that prevent methylation or inhibit deacetylation leaves the cancer vulnerable to alemtuzumab once again, allowing patients to enter remission. ©2015 American Ass
- PMID 26170393
- T-cell chronic lymphocytic leukemia or small-cell variant of T-cell prolymphocytic leukemia: a historical perspective and search for consensus.
- Rashidi A1, Fisher SI2.
- European journal of haematology.Eur J Haematol.2015 Sep;95(3):199-210. doi: 10.1111/ejh.12560. Epub 2015 Apr 24.
- There is a rich history behind the extinct entity 'T-cell chronic lymphocytic leukemia (T-CLL)' and the now-established replacement, small-cell variant of T-cell prolymphocytic leukemia (T-PLL-sv). Herein, we review the history of the events, observations, and discussions that led to this replacemen
- PMID 25846234
Japanese Journal
- 南野 弘明,町田 浩久,富永 和作,亀田 夏彦,岡崎 博俊,谷川 徹也,渡辺 憲治,渡辺 俊雄,藤原 靖弘,大澤 政彦,荒川 哲男
- 日本消化器内視鏡学会雑誌 53(2), 262-269, 2011
- 症例は37歳の女性．白血病の再発に対する化学療法施行中に，嘔気と心窩部痛が出現した．上部消化管内視鏡検査にて，胃の広範な領域に著明な粘膜肥厚・浮腫と発赤を認めた．生検病理組織にて胃放線菌症と診断し，抗菌薬で保存的に治療し得た．本邦で現在まで報告されている胃放線菌症6例は，悪性疾患が疑われ外科切除が施行されている．今回われわれは，内視鏡下生検にて診断し，保存的に治療し得た胃放線菌症の一例を経験した．
- NAID 130000655091
Related Links
- Prolymphocytic leukemia is divided into two types according to the kind of cell involved: B-cell prolymphocytic leukemia and T-cell prolymphocytic leukemia. It is usually classified as a kind of chronic lymphocytic leukemia.
- T-cell-prolymphocytic leukemia (T-PLL) is a mature T-cell leukemia with aggressive behavior and predilection for blood, bone marrow, lymph nodes, liver, spleen, and skin involvement. T-PLL is a very rare leukemia, primarily affecting adults ...
★リンクテーブル★
[★]
- 英
- chronic lymphocytic leukemia, chronic lymphoid leukemia, CLL
- 関
- 白血病
- first aid step1 2006 p.300,302,303,304,309,310,427,430
概念
- the accumulation of nonproliferating mature-appearing lymphocytes in the blood, marrow, lymph nodes, and spleen.
- monoclonal B lymphocytes.
- CD5+ and CD23+CD5, CD23
- derived from memory B cell.
細胞表面マーカー WCH.2438
臨床像
- HIM.693
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年齢
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子供における頻度
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男性(%)
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ステージI,II vs III,IV(%)
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B症状(%)
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骨髄浸潤(%)
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消化管浸潤(%)
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5年生存率(%)
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| B細胞CLL/小リンパ球性リンパ腫
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65
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まれ
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53
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9 vs 91
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33
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72
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3
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51
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疫学
- YN.G-49
- 全白血病の2-3%
- 60歳以上に多い。
- 男女比=2:1
病態
- YN.G-49
- 正常な免疫グロブリンの産生が抑制されるばかりでなく、異常な自己抗体を産生 → 続発性免疫不全症、自己免疫性溶血性貧血
USMLE
参考
- 1. [charged] Epidemiology and clinical manifestations of chronic lymphocytic leukemia - uptodate [1]
- 2. [charged] Pathologic features, diagnosis, and differential diagnosis of chronic lymphocytic leukemia - uptodate [2]
- 3. [charged] Pathophysiology and cytogenetics of chronic lymphocytic leukemia - uptodate [3]
[show details]
[★]
- 英
- prolymphocytic leukemia、((古))prolymphocytic leukaemia
- 関
- 前リンパ性白血病
[★]
- 英
- prolymphocytic leukemia、prolymphocytic leukaemia
- 関
- 前リンパ球性白血病
[★]
前リンパ球性白血病、前リンパ性白血病
- 関
- prolymphocytic leukemia
[★]
T細胞性前リンパ球性白血病、T細胞性前リンパ性白血病
- 関
- chronic lymphocytic leukemia、chronic T-cell leukemia、T-cell prolymphocytic leukaemia、T-PLL
[★]
B細胞性前リンパ球性白血病
[★]