WordNet

fill as much as possible; "brim a cup to good fellowship"
be completely full; "His eyes brimmed with tears"
the top edge of a vessel or other container (同)rim, lip
a circular projection that sticks outward from the crown of a hat
provide with an edge; "edge a blade"
a sharp side formed by the intersection of two surfaces of an object; "he rounded the edges of the box"
a slight competitive advantage; "he had an edge on the competition"
the outside limit of an object or area or surface; a place farthest away from the center of something; "the edge of the leaf is wavy"; "she sat on the edge of the bed"; "the waters edge"
the boundary of a surface (同)border
the attribute of urgency in tone of voice; "his voice had an edge to it" (同)sharpness
advance slowly, as if by inches; "He edged towards the car" (同)inch
the boundary line or the area immediately inside the boundary (同)border, perimeter
the amount of collateral a customer deposits with a broker when borrowing from the broker to buy securities (同)security deposit
an amount beyond the minimum necessary; "the margin of victory"
the blank space that surrounds the text on a page; "he jotted a note in the margin"
run around the rim of; "Sugar rimmed the dessert plate"
the shape of a raised edge of a more or less circular object
(basketball) the hoop from which the net is suspended; "the ball hit the rim and bounced off"
the outer part of a wheel to which the tire is attached
furnish with a rim; "rim a hat"
roll around the rim of; "the ball rimmed the basket"
(Old Testament) Gods means of destroying sinners; "his sermons were full of fire and brimstone"
a brim that can be turned up and down on opposite sides
a hat with a snap brim

PrepTutorEJDIC

(茶わん・コップなどの)『縁』,へり(rim) / (帽子の)『つば』 / (…で)縁まで満たされる,あふれそうになる《[+『over』]『with』+『名』》
〈C〉『縁』,『端』;(峰などの)背 / 〈C〉(刃物の)『刃』;〈U〉(刃の)鋭利さ / 〈U〉(欲望などの)強さ,激しさ / (…で)…‘に'『へり』(『縁』)『をつける』《+『名』+『with』+『名』》 / 《副詞[句]を伴って》…‘を'徐々に(注意深く)動かす / 〈ナイフなど〉‘を'研ぐ / 〈声・感覚など〉‘を'研ぎ澄ます / (相手)‘に'小差で勝つ / 横ざまに進む / じりじり進む
『へり』,『縁』,端(edge) / (ページの)『余白』,欄外 / (可能の)限界,限度 / (空間・時間・経費・活動などの)余裕,余地 / 利ざや,マージン,販売利益
(特に円形,またはカーブしたものの)『へり』,『縁』(ふち) / (車輪の)わく,リム / …にへり(縁,わく)をつける,‘を'縁どる / …の縁(へり)をぐるっと回る
(…が)縁までいっばいの,あふれるほどの《+『of』(『with』)+『名』》

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/10/27 21:04:42」(JST)

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UpToDate Contents

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1. 皮膚光線過敏症の概要：光生物学、患者評価、および光保護 overview of cutaneous photosensitivity photobiology patient evaluation and photoprotection
2. 正常妊娠における腎臓および尿路の生理機能 renal and urinary tract physiology in normal pregnancy
3. 女性における尿生殖路瘻 urogenital tract fistulas in women
4. 転移性黒色腫（メラノーマ）の分子標的療法 molecularly targeted therapy for metastatic melanoma
5. 卵巣レムナント症候群 ovarian remnant syndrome

English Journal

Pharmacodynamic Effects and Mechanisms of Resistance to Vemurafenib in Patients With Metastatic Melanoma.

Trunzer K, Pavlick AC, Schuchter L, Gonzalez R, McArthur GA, Hutson TE, Moschos SJ, Flaherty KT, Kim KB, Weber JS, Hersey P, Long GV, Lawrence D, Ott PA, Amaravadi RK, Lewis KD, Puzanov I, Lo RS, Koehler A, Kockx M, Spleiss O, Schell-Steven A, Gilbert HN, Cockey L, Bollag G, Lee RJ, Joe AK, Sosman JA, Ribas A.SourceKerstin Trunzer, Olivia Spleiss, Annette Schell-Steven, and Louise Cockey, F. Hoffmann-La Roche, Basel, Switzerland; Anna C. Pavlick and Patrick A. Ott, New York University Medical Center, New York, NY; Lynn Schuchter and Ravi K. Amaravadi, Abramson Cancer Center, University of Pennsylvania, Philadelphia; Stergios J. Moschos, University of Pittsburgh, Pittsburgh, PA; Rene Gonzalez and Karl D. Lewis, University of Colorado, Denver, CO; Grant A. McArthur, Peter MacCallum Cancer Centre, East Melbourne, Victoria; Peter Hersey, University of Newcastle, Newcastle; Georgina V. Long, Westmead Institute for Cancer Research and Westmead Hospital, University of Sydney, Sydney, New South Wales, Australia; Thomas E. Hutson, Texas Oncology-Baylor Sammons Cancer Center, Dallas; Kevin B. Kim, University of Texas MD Anderson Cancer Center, Houston, TX; Keith T. Flaherty and Donald Lawrence, Massachusetts General Hospital Cancer Center, Boston, MA; Jeffrey S. Weber, Moffitt Cancer Center, Tampa, FL; Igor Puzanov and Jeffrey A. Sosman, Vanderbilt-Ingram Cancer Center, Nashville, TN; Roger S. Lo and Antoni Ribas, Jonsson Comprehensive Cancer Center, University of California, Los Angeles; Houston N. Gilbert, Genentech, South San Francisco; Gideon Bollag, Plexxikon, Berkeley, CA; Astrid Koehler, Roche Diagnostics, Penzberg, Germany; Mark Kockx, HistoGeneX, Antwerp, the Netherlands; and Richard J. Lee and Andrew K. Joe, F. Hoffmann-La Roche, Nutley, NJ.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.J Clin Oncol.2013 Apr 8. [Epub ahead of print]
PURPOSETo assess pharmacodynamic effects and intrinsic and acquired resistance mechanisms of the BRAF inhibitor vemurafenib in BRAFV600-mutant melanoma, leading to an understanding of the mechanism of action of vemurafenib and ultimately to optimization of metastatic melanoma therapy. METHODSIn the
PMID 23569304

"Habitual Adnexal Torsions"-Recurrence after Two Oophoropexies in a Prepubertal Girl: A Case Report and Review of the Literature.

Sheizaf B, Ohana E, Weintraub AY.SourceDepartment of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel. Electronic address: bsheizaf@bgu.ac.il.
Journal of pediatric and adolescent gynecology.J Pediatr Adolesc Gynecol.2013 Mar 19. pii: S1083-3188(13)00063-6. doi: 10.1016/j.jpag.2013.01.060. [Epub ahead of print]
BACKGROUND: Recurrent adnexal torsion rarely affects girls. Various surgical techniques for its prevention are available. We describe a case of recurrent asynchronous bilateral torsions in a prepubertal patient.CASE: An 8-year-old girl first presented with a right adnexal torsion and underwent a lap
PMID 23518360

Short- and long-term risk of colorectal adenoma recurrence among whites and blacks.

Laiyemo AO, Doubeni C, Brim H, Ashktorab H, Schoen RE, Gupta S, Charabaty A, Lanza E, Smoot DT, Platz E, Cross AJ.SourceDepartment of Medicine, Howard University Hospital, Washington, DC, USA. adeyinka.laiyemo@howard.edu.
Gastrointestinal endoscopy.Gastrointest Endosc.2013 Mar;77(3):447-54. doi: 10.1016/j.gie.2012.11.027. Epub 2013 Jan 18.
BACKGROUND: It is unclear whether the higher burden from colorectal cancer among blacks is due to an increased biological susceptibility.OBJECTIVE: To determine whether non-Hispanic blacks (blacks) have a higher risk of adenoma recurrence than non-Hispanic whites (whites) after removal of colorectal
PMID 23337636

Memory in aged mice is rescued by enhanced expression of the GluN2B subunit of the NMDA receptor.

Brim BL, Haskell R, Awedikian R, Ellinwood NM, Jin L, Kumar A, Foster TC, Magnusson KR.SourceMolecular and Cellular Biosciences Program, Oregon State University, Corvallis, OR 97331, USA.
Behavioural brain research.Behav Brain Res.2013 Feb 1;238:211-26. doi: 10.1016/j.bbr.2012.10.026. Epub 2012 Oct 24.
The GluN2B subunit of the N-methyl-d-aspartate (NMDA) receptor shows age-related declines in expression across the frontal cortex and hippocampus. This decline is strongly correlated to age-related memory declines. This study was designed to determine if increasing GluN2B subunit expression in the f
PMID 23103326