HTLV-1関連脊髄症
WordNet
- having partial rights and privileges or subordinate status; "an associate member"; "an associate professor"
- a person who joins with others in some activity or endeavor; "he had to consult his associate before continuing"
- a person with subordinate membership in a society, institution, or commercial enterprise; "associates in the law firm bill at a lower rate than do partners"
- any event that usually accompanies or is closely connected with another; "first was the lightning and then its thunderous associate"
- make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all" (同)tie_in, relate, link, colligate, link up, connect
- write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
- a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
- (biology) the taxonomic group whose characteristics are used to define the next higher taxon
- a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
- all of the tokens of the same symbol; "the word `element contains five different types of character"
- printed characters; "small type is hard to read"
- identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
- sing with closed lips; "She hummed a melody"
- a humming noise; "the hum of distant traffic" (同)humming
- be noisy with activity; "This office is buzzing with activity" (同)buzz, seethe
- sound with a monotonous hum (同)thrum
- make a low continuous sound; "The refrigerator is humming"
- relating to a person; "the experiment was conducted on 6 monkeys and 2 human subjects"
- characteristic of humanity; "human nature"
- having human form or attributes as opposed to those of animals or divine beings; "human beings"; "the human body"; "human kindness"; "human frailty"
- a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
- (virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
- a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
PrepTutorEJDIC
- 〈人〉'を'(…の)『仲間に加える』,(…に)連合させる《+『名』〈人〉+『with』+『名』》 / (…と)…'を'結びつけて考える(起こす)《+『名』+『with』+『名』》 / (…と)『仲間になる』,交際する《+『with』+『名』》 / (…と)合体する,提携する《+『with』+『名』》 / 『仲間』,『同僚』;組合員 / 準会員 / 付属物;連想されるもの / 連合した;仲間の,同僚の / 補助の,準…
- 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
- 〈ハチ・機械などが〉『ブンブンいう』,ブーンと鳴る / 『鼻歌を歌う』,ハミングスル / (ちゅうちょ・当惑で)ふむふむいう / 《話》〈雰囲気・事業などが〉活気がある,活発に動く;(…で)活気づく《+『with』+『名』》 / …‘を'『ハミングで歌う』,鼻歌を歌って…‘を'(ある状熊に)する / (ハチ・機械などの)『ブンブン』[『うなる音』];鼻歌 / (雑踏などの)ガヤガヤ]いう音],騒音 / ふ‐む,う‐ん(ちゅうちょ・当惑・黙考・疑惑・不快などの声)
- (動物・神に対して)『人間の』,人の / 『人間らいし』,人間的な,人情味のある / 〈C〉《複数形》(動物に怠して)人間(human being) / 〈U〉《the human》人類
- ビールス,ろ過性病原体
UpToDate Contents
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English Journal
- Clinical and laboratory features of HTLV-I asymptomatic carriers and patients with HTLV-I-associated myelopathy/tropical spastic paraparesis from the Brazilian Amazon.
- Takatani M1, Crispim ME2, Fraiji N2, Stefani MM3, Kiesslich D2.
- Revista do Instituto de Medicina Tropical de Sao Paulo.Rev Inst Med Trop Sao Paulo.2017 Apr 3;59:e5. doi: 10.1590/S1678-9946201759005.
- PMID 28380116
- Tumor necrosis factor alpha inhibitors have no effect on a human T-lymphotropic virus type-I (HTLV-I)-infected cell line from patients with HTLV-I-associated myelopathy.
- Fukui S1, Nakamura H2, Takahashi Y1, Iwamoto N1, Hasegawa H3, Yanagihara K3, Nakamura T4, Okayama A5, Kawakami A1.
- BMC immunology.BMC Immunol.2017 Feb 3;18(1):7. doi: 10.1186/s12865-017-0191-2.
- PMID 28158970
- New directions for protease inhibitors directed drug discovery.
- Hamada Y1, Kiso Y2.
- Biopolymers.Biopolymers.2016 Nov 4;106(4):563-79. doi: 10.1002/bip.22780.
- PMID 26584340
Japanese Journal
- Prosultiamine treatment as a new therapeutic strategy in human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis
- Nakamura Tatsufumi
- Clinical and Experimental Neuroimmunology 4(3), 259-260, 2013-12
- NAID 120005367573
- Efficacy of prosultiamine treatment in patients with human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis: results from an open-label clinical trial
- Nakamura Tatsufumi,Matsuo Tomohiro,Fukuda Taku,Yamato Shinji,Yamaguchi Kentaro,Kinoshita Ikuo,Matsuzaki Toshio,Nishiura Yoshihiro,Nagasato Kunihiko,Narita-Masuda Tomoko,Nakamura Hideki,Satoh Katsuya,Sasaki Hitoshi,Sakai Hideki,Kawakami Atsushi
- BMC Medicine 11(1), 182, 2013-08-15
- … Background: Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic myelopathy characterized by motor dysfunction of the lower extremities and urinary disturbance. …
- NAID 120005353322
- Clinical studies on rising and re-rising neurological diseases in Japan - A personal contribution -:– A personal contribution –
- Igata Akihiro
- Proceedings of the Japan Academy, Series B 86(4), 366-377, 2010
- … Throughout my research life, I experienced to discover the causes of some neurological diseases in Japan.1) SMON (subacute myelo-optico-neuropathy). … This discovery is a big topic in the history of Japanese medicine.2) In early 1970s, I experienced many young patients with oedema and polyneuropathy in Kagoshima. …
- NAID 130000258734
Related Links
- Human T-lymphotropic virus type 1 (HTLV-1), a human retrovirus, is the causative agent of a progressive neurological disease termed HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HAM/TSP is a chronic ...
- [Interferon-alpha for the treatment of retinal vasculitis associated with human T-lymphotropic virus type I myelopathy (HAM)] Nippon Ganka Gakkai Zasshi. 1990 Aug; 94(8):769-73. [Nippon Ganka Gakkai Zasshi. 1990] Presence of ...
Related Pictures
★リンクテーブル★
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- 英
- HTLV-1-associated myelopathy HTLV-1 associated myelopaty, HTLV-I-associated myelopathy HTLV-I associated myelopathy、human T-lymphotropic virus type I-associated myelopathy, HAM
- 同
- HTLV-I脊髄症、ヒトTリンパ好性ウイルスI型関連脊髄症、HTLV-I型関連ミエロパシー、ヒトTリンパ球向性ウイルスI型関連脊髄症
- 関
- 熱帯性痙性不全対麻痺症 TSP tropical spastic paraparesis、HAM/TSP、ヒトTリンパ球向性ウイルス
[show details]
概念
疫学
- 世界の患者数は3000人、日本は約1400人である。
- 男女比=1:2~2.5
- 年齢:11~80歳(平均41.2歳)/6-78歳(発症は平均で40歳代後半~50歳代前半)(IMD)
- HTLV-Iキャリアの1300人中1人の割合で発症。
潜伏期
- 感染経路により異なり、母子感染では発症まで数十年、輸血では半年~数年かかる。
病態
- 主に胸髄を障害する。障害部位では萎縮・白質変性が認められる。特に側索の錐体路で顕著である(錐体路症状を来す)。同部位では脊髄髄膜は肥厚し、慢性脊髄炎の所見が認められる。
症候
- 歩行障害(100%)、排尿障害(93%)、感覚障害(56%)。初発症状はこのいずれでもあり売る
治療
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- 英
- human T-lymphotropic virus type I-associated myelopathy
- 関
- HTLV-I関連脊髄症、ヒトTリンパ好性ウイルスI型関連脊髄症
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- 結合する、連合させる。連想によって結びつける。(人を)仲間/友達などとしての関係に置く。(化)会合させる
- 仲間/友人などとして交際する(with)。一つにまとめる、連合する
- 仕事仲間、提携者、同僚。友人、朋友。準会員。従業員、社員
- 密接な蒸す偽付きのある物、付随する物、つきもの。準国家
- 連想によって心に浮かぶ言葉/思い、連想物
- 仲間の、同僚の。製紙機械員に次ぐ資格の
- 付随する、連想される
- 関
- accompany、association、associative、attach、bearing、bind、binding、bond、bonding、coassemble、colleague、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、correlate、correlation、couple、dock、engage、engagement、federation、implication、join、joint、ligate、link、linkage、peer、pertinent、reference、relate、relation、relationship、relative、relevance、relevant、symphysial、union
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- (windows)ファイル内容表示(linux -> cat])
- ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html
- 関
- form、mode、pattern、type specimen、typed
[★]
- 関
- ape、hominid、Hominidae、homo、Homo sapiens、human being、human race、human-type、man、Pongidae
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