グルタミン酸トランスポーター遮断薬
WordNet
- a three-dimensional shape with six square or rectangular sides (同)cube
- (computer science) a sector or group of sectors that function as the smallest data unit permitted; "since blocks are often defined as a single sector, the terms `block and `sector are sometimes used interchangeably"
- support, secure, or raise with a block; "block a plate for printing"; "block the wheels of a car"
- a solid piece of something (usually having flat rectangular sides); "the pyramids were built with large stone blocks"
- housing in a large building that is divided into separate units; "there is a block of classrooms in the west wing"
- a rectangular area in a city surrounded by streets and usually containing several buildings; "he lives in the next block" (同)city block
- an inability to remember or think of something you normally can do; often caused by emotional tension; "I knew his name perfectly well but I had a temporary block" (同)mental_block
- a number or quantity of related things dealt with as a unit; "he reserved a large block of seats"; "he held a large block of the companys stock"
- interrupt the normal function of by means of anesthesia; "block a nerve"; "block a muscle"
- run on a block system; "block trains"
- shape by using a block; "Block a hat"; "block a garment"
- shape into a block or blocks; "block the graphs so one can see the results clearly"
- stamp or emboss a title or design on a book with a block; "block the book cover"
- move something or somebody around; usually over long distances
- an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
- move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
- transport commercially (同)send, ship
- a long truck for carrying motor vehicles (同)car transporter
- a crane for moving material with dispatch as in loading and unloading ships
- a class of drugs that inhibit (block) some biological process (同)blocking_agent
- a football player whose responsibility is to block players attempting to stop an offensive play
- a salt or ester of glutamic acid
PrepTutorEJDIC
- (木・石などの,通例平らな面のある)『かたまり』 / 《米》(四団を街路に囲まれた)『区画』,街区 / 街区の1辺の距離(一般に40メートル前後) / 《英》ブロック(アパート・事務所・商店などに区切られている大きな建物) / 『妨害物』,障害物(obstacle);(障害によって生じた)停滞,渋滞 / 台木,台(まないた・肉切り台・まき割り台・せり売り台・帽子の木型など);《the~》炭頭台 / (特にアメリカンフットボールで)ブロック(相手の選手の突進を阻止する) / 滑車(pulley) / (座席券・株券などの)一組《+『of』+『名』》 / 〈通路など〉'を'『ふさぐ』,〈通行・進行など〉'を'妨げる / 〈帽子など〉の型取りをする / (特にアメリカンフットボールで)〈相手選手の突進〉'を'ブロックする;(ボクシングで)〈相手のパンチ〉'を'ブロックする
- (ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機
- 自動車運搬用大型トラック
UpToDate Contents
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English Journal
- A novel method for simultaneous glutamate and extracellular activity measurement in brain slices with high temporal resolution.
- López-Valenzuela CL1, Morales-Villagrán A2, Medina-Ceja L1.
- Talanta.Talanta.2015 Nov 1;144:1231-8. doi: 10.1016/j.talanta.2015.08.013. Epub 2015 Aug 6.
- Measurement of neurotransmitters during normal or altered function in cerebral slices could be an important tool to better understand the relationship between biochemical changes and electrophysiological activity. Some attempts of this analysis have been made; however, the current techniques do not
- PMID 26452952
- Tumor necrosis factor-mediated downregulation of spinal astrocytic connexin43 leads to increased glutamatergic neurotransmission and neuropathic pain in mice.
- Morioka N1, Zhang FF2, Nakamura Y2, Kitamura T2, Hisaoka-Nakashima K2, Nakata Y2.
- Brain, behavior, and immunity.Brain Behav Immun.2015 Oct;49:293-310. doi: 10.1016/j.bbi.2015.06.015. Epub 2015 Jun 24.
- Spinal cord astrocytes are critical in the maintenance of neuropathic pain. Connexin 43 (Cx43) expressed on spinal dorsal horn astrocytes modulates synaptic neurotransmission, but its role in nociceptive transduction has yet to be fully elaborated. In mice, Cx43 is mainly expressed in astrocytes, no
- PMID 26116449
- A novel cognitive impairment mechanism that astrocytic p-connexin 43 promotes neuronic autophagy via activation of P2X7R and down-regulation of GLT-1 expression in the hippocampus following traumatic brain injury in rats.
- Sun L1, Gao J2, Zhao M2, Cui J3, Li Y1, Yang X1, Jing X4, Wu Z5.
- Behavioural brain research.Behav Brain Res.2015 Sep 15;291:315-24. doi: 10.1016/j.bbr.2015.05.049. Epub 2015 May 29.
- Connexin 43 (Cx43) is one of the major gap junction proteins in astrocytes. Our previous studies reported that astrocytic phosphorylated Cx43 (p-CX43) regulated neuronic autophagy levels in the rat hippocampus after traumatic brain injury (TBI). In this study, we explored the underlying molecular me
- PMID 26031379
Japanese Journal
- Reversed operation of glutamate transporter GLT-1 is crucial to the development of preconditioning-induced ischemic tolerance of neurons in neuron/astrocyte co-cultures
- Kawahara Koichi,Kosugi Tatsuro,Tanaka Motoki,Nakajima Takayuki,Yamada Takeshi
- Glia 49(3), 349-359, 2005-02
- … In the present study, we investigated the roles of the astrocytic glutamate (Glu) transporter GLT-1 in preconditioning (PC)-induced neuronal ischemic tolerance in cortical neuron/astrocyte co-cultures. … Treatment with a GLT-1 blocker during PC suppressed this increase in Glu significantly, and antagonized the PC-induced neuronal ischemic tolerance. …
- NAID 120000963298
- Selective blockade of astrocytic glutamate transporter GLT-1 with dihydrokainate prevents neuronal death during ouabain treatment of astrocyte/neuron cocultures
- Kawahara Koichi,Hosoya Rui,Sato Hideomi,Tanaka Motoki,Nakajima Takayuki,Iwabuchi Sadahiro
- Glia 40(3), 337-349, 2002-12
- … Glutamate (Glu) is a major excitatory neurotransmitter of the mammalian central nervous system and under normal conditions plays an important role in information processing in the brain. … In this study, using mixed neuron/astrocyte cultures, we investigated whether astrocytic Glu transporter GLT-1 is crucial to the survival of neurons under various conditions. …
- NAID 120000959801
- P2-36 グルタミン酸トランスポーター阻害剤IDL-TBOAのうま味応答への影響
★リンクテーブル★
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- 英
- glutamate transporter blocker
- 関
- グルタミン酸トランスポーター
[show details]
グルタミン酸輸送体阻害薬 : 13 件
グルタミン酸トランスポーター阻害薬 : 23 件
グルタミン酸トランスポータ阻害薬 : 31 件
グルタミン酸輸送体遮断薬 : 3 件
グルタミン酸トランスポーター遮断薬 : 約 12,700 件
グルタミン酸トランスポータ遮断薬 : nothing
[★]
- 関
- blockade、blockage、deter、inhibit、inhibition、lump、prevent、prevention、repress、repression、seal、turn off
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- 関
- bring、carriage、carry、convey、delivery、ship、traffic、trafficking、transportation
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- 関
- amino acid transport system X-AG、glutamate-aspartate transporter
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- 関
- antagonist、blocking agent、inhibitor
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グルタミン酸、グルタメート、グルタメイト、(化合物)グルタミン酸塩