WordNet
- make complete or perfect; supply what is wanting or form the complement to; "I need some pepper to complement the sweet touch in the soup"
- a complete number or quantity; "a full complement"
- one of a series of enzymes in the blood serum that are part of the immune response
- something added to complete or embellish or make perfect; "a fine wine is a perfect complement to the dinner"; "wild rice was served as an accompaniment to the main dish" (同)accompaniment
- number needed to make up a whole force; "a full complement of workers" (同)full complement
- a word or phrase used to complete a grammatical construction
- either of two parts that mutually complete each other
- the concentration of a solution as determined by titration (同)titre
PrepTutorEJDIC
- (あるものを完全にするため)(…を)補う物(事)《+『of』+『名』》 / 補語(文法で文の成分の一つ) / (必要な)全数,全量;(船の)定員 / …を補足する,補う
- 軽打 / しっぺい返しとして
- =titmouse
- 乳首;乳房
UpToDate Contents
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- 1. 補体系の概要および臨床的評価 overview and clinical assessment of the complement system
- 2. 補体系の後天性欠損 acquired deficiencies of the complement system
- 3. 補体系の遺伝性疾患 inherited disorders of the complement system
- 4. 補体系の制御因子および受容体 regulators and receptors of the complement system
- 5. 補体経路 complement pathways
English Journal
- The complement-mediated prozone effect in the Luminex single-antigen bead assay and its impact on HLA antibody determination in patient sera.
- Weinstock C, Schnaidt M.SourceGerman Red Cross Blood Service Baden-Württemberg-Hessen, Institute Ulm; Institute of Clinical Transfusion Medicine and Immunogenetics, Institute of Transfusion Medicine, University of Ulm, Ulm, Germany.
- International journal of immunogenetics.Int J Immunogenet.2013 Jun;40(3):171-7. doi: 10.1111/j.1744-313X.2012.01147.x. Epub 2012 Aug 23.
- The Luminex xMAP system has become an important tool for HLA antibody screening and identification in sera of transplant patients. Recently, the Luminex single antigen bead assay was shown to be prone to an artefact, the so called prozone phenomenon: Sera with high titer HLA antibodies gave negative
- PMID 22913810
- Targeting of Antigens to B Lymphocytes via CD19 as a Means for Tumor Vaccine Development.
- Ma Y, Xiang D, Sun J, Ding C, Liu M, Hu X, Li G, Kloecker G, Zhang HG, Yan J.SourceTumor Immunobiology Program, James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, KY 40202;
- Journal of immunology (Baltimore, Md. : 1950).J Immunol.2013 Jun 1;190(11):5588-99. doi: 10.4049/jimmunol.1203216. Epub 2013 Apr 29.
- Ab therapy against surface Ags on tumor cells has demonstrated significant efficacy for some cancers. However, it is costly and patients frequently develop acquired resistance over time. In cases of Ab therapy resistance, T cell responses have been shown to be essential in controlling disease progre
- PMID 23630363
Japanese Journal
- 経過良好な、マイコプラズマ感染症関連Opsoclonus-Myoclonus症候群の1例
- 河野 香/伊藤 康/石塚 喜世伸/西川 愛子/佐原 真澄/平野 嘉子/石垣 景子/舟塚 真/高橋 幸利/大澤 眞木子
- 東京女子医科大学雑誌 83(E1), E336-E341, 2013-01-31
- Opsoclonus-myoclonus syndrome(OMS)は,左右共同性の不規則で多方向性の異常眼球運動,顔面,頭部,体幹などに出現するmyoclonus,小脳失調を特徴とする症候群である.小児において,腫瘍,感染,予防接種などが誘因となり,半数に神経芽細胞腫を合併する.症例は4歳9ヵ月の女児.生後11ヵ月時にマイコプラズマ感染を契機にOMSを発症した.血清マイコプラズマ抗体価(PA法) …
- NAID 110009559410
- Mixed Connective Tissue Disease Developing into MPO-ANCA-positive Polyangiitis
- Murakami Taichi,Endo Shuichiro,Moriki Toshiaki,Doi Toshio,Matsumoto Yoshihiro
- Internal Medicine 50(6), 591-595, 2011
- … Myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA) was positive with a titer of 59.0 EU. … Anti-DNA antibody and complement levels were normal. …
- NAID 130000649891
Related Links
- The optimum conditions for the assay of the hemolytic complement titer (CH,, unit/ml) of carp, Cyprinus carpio, was investigated by use of sheep red blood ceils (SRBC) sensitized with carp antiserum. The antiserum was obtained ...
- Complement-mediated bactericidal antibodies in serum confer protection against meningococcal disease. The minimum protective titer is estimated to be between 1:4 and 1:8 when measured by the Goldschneider assay performed ...
Related Pictures
★リンクテーブル★
| リンク元 | 「補体価」「補体値」「complement titre」「complement activity」 |
| 関連記事 | 「complement」「titer」 |
「補体価」
- 英
- complement activity, complement titer
- 同
- 血清補体価 serum complement level, serum complement titer
- 関
- CH50
概念
- 抗体に感作されたヒツジ抗体を50%溶血を生じさせる血清量。
- 補体活性の指標となる；古典経路と共通経路の評価。
正常値
- 70-110 CH50
補体価が変化する病態 (OLM.394)
高値
- 炎症疾患
低値
- (1)産生低下による病態
- 1. 後天性産生低下
- 重症肝障害(肝硬変、劇症肝炎、慢性肝炎)
- 2. 先天性産生低下
- (2)補体活性が亢進する病態
- 1. 古典経路が活性化される病態
- 2. 代替経路が亢進する病態
← 補体価では代替経路は評価していない ← どういうこと？
- (3)補体成分の異化が亢進する病態
- 蛋白質漏出性病態(肝機能が保たれていれば、補償される)
- (4)cold activation
- 生体外で肝や血清を放置すると古典経路が活性化される状態で、血清抗体価は減少するが補体成分タンパク量は減少しない。EDTAを抗凝固剤として用いるとこの現象はみられない。 ← ？
- 慢性C型肝炎、肝硬変、混合型クリオグロブリン血症
血清補体価の低下
- 血清補体価の低下が疾患の高活動性
国試
「補体値」
「complement titre」
「complement activity」
「complement」
- n.
- 補って完全にする物、補完物。(免疫)補体
- (必要な)全数、善良
- vt.
- 補って完全にする。補完する。～の補足となる。
「titer」
- n.