WordNet
- desert (a cause, a country or an army), often in order to join the opposing cause, country, or army; "If soldiers deserted Hitlers army, they were shot" (同)desert
- an imperfection in an object or machine; "a flaw caused the crystal to shatter"; "if there are any defects you should send it back to the manufacturer" (同)fault, flaw
- an imperfection in a bodily system; "visual defects"; "this device permits detection of defects in the lungs"
- a failing or deficiency; "that interpretation is an unfortunate defect of our lack of information" (同)shortcoming
- move, travel, or proceed toward some place; "He repaired to his cabin in the woods" (同)resort
- restore by replacing a part or putting together what is torn or broken; "She repaired her TV set"; "Repair my shoes please" (同)mend, fix, bushel, doctor, furbish up, restore, touch_on
- a formal way of referring to the condition of something; "the building was in good repair"
- the act of putting something in working order again (同)fix, fixing, fixture, mend, mending, reparation
- of or relating to a chromosome; "chromosomal defect"
PrepTutorEJDIC
- 〈C〉『欠点』,弱点,欠陥 / 〈U〉〈C〉《古》不足,欠乏 / (国・党・主義などから)離脱する,裏切って出る《+『from』+『名』》;離反して(…に)転向する《+『to』+『名』》
- …‘を'『修繕する』,修理する / …‘を'『償う』;…‘を'訂正する』 / …‘を'回復する / 修繕(修理)できる / 『修繕』,『修理』,修繕作業 / 〈U〉手入れ(修理)の状態
- (大挙して)(…へ)行く(GO)《+『to』+『名』》
UpToDate Contents
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English Journal
- Increased frequency of 20q gain and copy-neutral loss of heterozygosity in mismatch repair proficient familial colorectal carcinomas.
- Middeldorp A, van Eijk R, Oosting J, Forte GI, van Puijenbroek M, van Nieuwenhuizen M, Corver WE, Ruano D, Caldes T, Wijnen J, Morreau H, van Wezel T.SourceDepartment of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
- International journal of cancer. Journal international du cancer.Int J Cancer.2012 Feb 15;130(4):837-46. doi: 10.1002/ijc.26093. Epub 2011 Jul 15.
- Many hereditary nonpolyposis colorectal cancers (CRCs) cannot be explained by Lynch syndrome. Other high penetrance genetic risk factors are likely to play a role in these mismatch repair (MMR)-proficient CRC families. Because genomic profiles of CRC tend to vary with CRC susceptibility syndromes, o
- PMID 21445971
Japanese Journal
- Epigenetic defects of XRCC3 and XRCC5 induced by E6 oncoprotein may enhance benzo[a]pyrene-induced chromosome instability in lung cancer cells
- CHENG Ya Wen,LEE Huei
- 日本毒性学会学術年会 39.2(0), AP-110, 2012
- … We therefore hypothesized that HPV infection could synergistically increased chromosomal instability (CIN) induced by B[a]P-DNA adducts and might contribute to lung tumorigenesis. … We next questioned whether B[a]P-induced CIN enhanced by E6 could be through altering DNA repair gene expressions. …
- NAID 130005009045
- Essential roles of Snf21, a Swi2/Snf2 family chromatin remodeler, in fission yeast mitosis
- Yamada Kentaro,Hirota Kouji,Mizuno Ken-ichi [他],SHIBATA Takehiko,OHTA Kunihiro
- Genes & genetic systems 83(5), 361-372, 2008-10-25
- … Recent studies have revealed that ADCRs play diverse regulatory roles in chromosomal events such as DNA repair and recombination. … A temperature sensitive allele of snf21+, snf21-36 exhibits at non-permissive temperature (34°C) a cell cycle arrest at G2-M phase and defects in chromosome segregation, thereby causing cell elongation, lack of cell growth, and death of some cell population. …
- NAID 10023887824
Related Links
- Abstract • Key points • Introduction • Targeting topoisomerases in cancer therapy • Chromosomal PDB repair • PDBs, carcinogenesis and transcription • Summary and future directions • References • Acknowledgements • Author ...
- Abstract DNA repair mechanisms are essential for the maintenance of genomic integrity. Disruption of gene products responsible for DNA repair can result in chromosomal damage. Improperly ...
★リンクテーブル★
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- 関
- aberrant、aberrantly、aberration、abnormal、abnormality、abnormally、absence、agenesis、anomalous、anomalously、anomaly、defective、deficiency、deficient、deficit、deletion、deletional、deviant、drawback、extraordinarily、extraordinary、fault、flaw、inadequacy、miss、missing、morphological defect、shortcoming、unusual、unusually、weakness
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- 関
- chromosomally、chromosome