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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/04/12 17:10:39」(JST)

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English Journal

  • A systematic review of interventions for children with cerebral palsy: state of the evidence.
  • Novak I, McIntyre S, Morgan C, Campbell L, Dark L, Morton N, Stumbles E, Wilson SA, Goldsmith S.SourceCerebral Palsy Alliance, Sydney, Australia; University of Notre Dame Australia, Sydney, Australia.
  • Developmental medicine and child neurology.Dev Med Child Neurol.2013 Oct;55(10):885-910. doi: 10.1111/dmcn.12246. Epub 2013 Aug 21.
  • AIM: The aim of this study was to describe systematically the best available intervention evidence for children with cerebral palsy (CP).METHOD: This study was a systematic review of systematic reviews. The following databases were searched: CINAHL, Cochrane Library, DARE, EMBASE, Google Scholar MED
  • PMID 23962350
  • Prophylactic and therapeutic functions of drug combinations against noise-induced hearing loss.
  • Bao J, Hungerford M, Luxmore R, Ding D, Qiu Z, Lei D, Yang A, Liang R, Ohlemiller KK.SourceDepartment of Otolaryngology, Center for Aging, Washington University School of Medicine, 4560 Clayton Avenue, St. Louis, MO 63110, USA. Electronic address:
  • Hearing research.Hear Res.2013 Oct;304:33-40. doi: 10.1016/j.heares.2013.06.004. Epub 2013 Jun 18.
  • Noise is the most common occupational and environmental hazard. Noise-induced hearing loss (NIHL) is the second most common form of sensorineural hearing deficit, after age-related hearing loss (presbycusis). Although promising approaches have been identified for reducing NIHL, currently there are n
  • PMID 23792074
  • Ionized hypocalcemia is an early event and is associated with organ dysfunction in children admitted to the intensive care unit.
  • Dias CR, Leite HP, Nogueira PC, Brunow de Carvalho W.SourcePediatric Intensive Care Unit, Department of Pediatrics, the Federal University of São Paulo.
  • Journal of critical care.J Crit Care.2013 Oct;28(5):810-5. doi: 10.1016/j.jcrc.2013.03.019. Epub 2013 May 15.
  • PURPOSE: The purpose was to determine the frequency and risk factors of ionized hypocalcemia and to evaluate this disturbance as a predictor of mortality in a pediatric intensive care unit (ICU).MATERIALS AND METHODS: In a prospective cohort study, 337 children admitted consecutively to an ICU were
  • PMID 23683566

Japanese Journal

  • 抗てんかん薬長期投与中に急性めまい・眼球運動異常をきたした1症例
  • 小山 京子,矢部 多加夫,井上 雄太
  • Equilibrium research 71(4), 231-236, 2012-08-01
  • A 42-years-old woman who had dizziness for the previous 10 days visited our hospital. She had experienced epileptic attacks and suffered from repeated seizures. She was under treatment with 4 antiepil …
  • NAID 10031026728
  • 加齢に伴う認知機能障害を標的とした薬物治療戦略
  • Ming Teng Koh,古屋敷 智之 [訳]
  • 日本薬理學雜誌 = Folia pharmacologica Japonica 139(4), 157-159, 2012-04-01
  • … Therapies to counter such excess activity might include antiepileptics or agonists for GABAA <I>α</I>5 receptors, which regulate tonic inhibition. … Instead, aged rats showed improved memory after treatment with selective GABAA <I>α</I>5 agonists and with certain antiepileptics. …
  • NAID 10030572419
  • Chronic Diarrhea as the Presenting Complaint of Systemic Lupus Erythematosus in a Man
  • Rajendiran Ashwin,Viswanathan Stalin,Remalayam Bhavith,Muthu Vivekanandan,Alexander Thomas
  • Internal Medicine 51(22), 3131-3134, 2012
  • … He is currently under regular follow-up care and receives antiepileptics, antihypertensives, diltiazem, amiodarone and warfarin. …
  • NAID 130003307900

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Related Pictures

Summary of Antiepileptic DrugsJCDA - Journal of the Canadian Dental Figure 5. A & b Proposed mechanisms of 2008 Revenue of Antiepileptic DrugsAntiepileptics by HPLC (Reversed Phase) few interactions with other antiepileptics

リンク元抗てんかん薬」「anticonvulsants」「antiepileptic agent



antiepileptic drug, antiepileptic antiepileptics


薬物 大発作 小発作 皮質焦点発作 精神運動発作 ミクローヌス発作 異型小発作 てんかん重積 二次的全般発作 副作用 作用機序
バルビツール酸 フェノバルビタール             眠気、呼吸抑制、ポルフィリン尿症 GABAA受容体に作用
プリミドン × ×        
ヒダントイン フェニトイン ×           小脳症状(萎縮)、肝障害、骨髄抑制、
オキサゾリジン トリメタジオン   *1             催奇形性(最強) シナプス前・後部に作用し伝達物質放出と
サクシニミド エトスクシミド                 Cl-チャネルを開口させることによって、
フェニル尿素 アセチルフェネトライド       *2            
イミノスチルベン カルバマゼピン             小脳症状、発疹、骨髄抑制、肝障害 Naチャネルをブロックする
ベンズイソキサゾール ゾニサミド         体重減少、眠気、腎尿管結石 T型のCa2+電流を抑制、
炭酸脱水素酵素阻害薬 アセタゾラミド             炭酸脱水素酵素阻害
ベンゾジアゼピン ジアゼパム           *3   呼吸抑制、眠気 GABAA受容体に作用
クロナゼパム             眠気、めまい、小脳症状
GABA分解酵素阻害薬 バルプロ酸 *4 悪心・嘔吐、肝障害、
*1 第一選択薬ではない
*2 他薬が無効な精神運動発作のみに使用
*3 てんかん重積の第一選択薬
*4 第一選択薬



  • 部分発作:カルバマゼピン、バルプロ酸
  • 全般発作:バルプロ酸フェニトイン
  • ミオクローヌス発作:クロナゼパム




anticonvulsantanticonvulsant agentanticonvulsant drugantiepileptic agentantiepileptic drugantiepilepticsantiseizure drug
Antiseizure drug(s)

antiepileptic agent」


anticonvulsant druganticonvulsantsantiepilepticantiepileptic drugantiepileptics



  • adj.
  • 抗てんかんの
  • n.