催奇形因子
WordNet
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
- of or relating to substances or agents that can interfere with normal embryonic development
- any agent that interferes with normal embryonic development: alcohol or thalidomide or X-rays or rubella are examples
PrepTutorEJDIC
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
UpToDate Contents
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English Journal
- Maternal and foetal adverse events with tumour necrosis factor-alpha inhibitors in inflammatory bowel disease.
- Deepak P1, Stobaugh DJ.
- Alimentary pharmacology & therapeutics.Aliment Pharmacol Ther.2014 Nov;40(9):1035-43. doi: 10.1111/apt.12936. Epub 2014 Aug 28.
- BACKGROUND: Transplacental transfer of tumour necrosis factor-alpha (TNF-α) inhibitors has been shown in mothers receiving therapy for inflammatory bowel disease (IBD).AIM: To examine reports of adverse events of these medications in pregnancy.METHODS: Individual Safety Reports of adverse events (J
- PMID 25164260
- Inhibition of DNA Topoisomerase II Selectively Reduces the Threat of Tumorigenicity Following Induced Pluripotent Stem Cell-Based Myocardial Therapy.
- Wyles SP1, Yamada S, Oommen S, Maleszewski JJ, Beraldi R, Martinez-Fernandez A, Terzic A, Nelson TJ.
- Stem cells and development.Stem Cells Dev.2014 Oct 1;23(19):2274-82. doi: 10.1089/scd.2014.0259. Epub 2014 Aug 21.
- The advent of induced pluripotent stem cell (iPSC) technology creates new opportunities for transplant-based therapeutic strategies. The potential for clinical translation is currently hindered by the risk of dysregulated cell growth. Pluripotent stem cells reprogrammed by three-factor (Sox2, Klf, a
- PMID 25036735
- Chronic prenatal ethanol exposure alters expression of central and peripheral insulin signaling molecules in adult guinea pig offspring.
- Dobson CC1, Thevasundaram K1, Mongillo DL1, Winterborn A2, Holloway AC3, Brien JF4, Reynolds JN5.
- Alcohol (Fayetteville, N.Y.).Alcohol.2014 Sep 6. pii: S0741-8329(14)00153-0. doi: 10.1016/j.alcohol.2014.09.001. [Epub ahead of print]
- Maternal ethanol consumption during pregnancy can produce a range of teratogenic outcomes in offspring. The mechanism of ethanol teratogenicity is multi-faceted, but may involve alterations in insulin and insulin-like growth factor (IGF) signaling pathways. These pathways are not only important for
- PMID 25278255
Japanese Journal
- サリドマイド催奇性の原因因子の発見から創薬への展開
- Teratogenic Factors Affect Transcription Factor Expression
- Bioscience, biotechnology, and biochemistry 77(5), 1035-1041, 2013-05-23
- NAID 10031177593
- 免疫調節薬サリドマイド : 薬理学的効果とその適応
- 日本臨床免疫学会会誌 = Japanese journal of clinical immunology 33(5), 229-233, 2010-10-31
- NAID 10027753813
Related Links
- Several factors affect the ability of a teratogen to contact a developing conceptus, such as the nature of the agent itself, route and degree of maternal exposure, rate of placental transfer and systemic absorption, and composition of the maternal ...
- teratogen. Genetics Any agent, chemical, or factor that causes a physical defect in a developing embryo or fetus; maternal medications with known teratogenic effects include aminopterin–spontaneous abortion, malformations; anticoagulants; ...
★リンクテーブル★
[★]
- 英
- teratogen, teratogenic factor
- 同
- 催奇形性物質、催奇形物質、奇形発生因子、催奇形剤
L.138
| 催奇形因子
|
先天異常
|
| 感染因子
|
風疹
|
白内障,緑内障,心臓異常,聾,歯異常
|
| サイトメガロウイルス
|
小頭症,盲目,精神発達遅滞,胎児死亡
|
| 単純ヘルペスウイルス
|
小眼球症,小頭症,網膜異形成
|
| 水痘ウイルス
|
肢低形成,精神発達遅滞,筋萎縮
|
| HIV
|
小頭症,発育遅延
|
| トキソプラズマ症
|
水頭症,大脳実質石灰化,小眼球症
|
| 梅毒
|
精神発達遅滞,聾
|
| 物理的因子
|
X線
|
小頭症,脊椎裂,口蓋裂,四肢の異常
|
| 高熱
|
無脳症
|
| 化学的因子
|
サリドマイド
|
四肢の異常,心臓異常
|
| アミノプテリン
|
無脳症,水頭症,唇裂と口蓋裂
|
| ジフェニルヒダントイン(フェニトイン)
|
胎児性ヒダントイン症候群：顔面異常,精神発達遅滞
|
| バルプロ酸
|
神経管異常,心,頭蓋顔面,肢異常
|
| トリメタジオン
|
口蓋裂,心臓異常,泌尿生殖器と骨格の異常
|
| リチウム
|
心臓異常
|
| アンフェタミン
|
唇裂と口蓋裂,心臓異常
|
| ワルファリン
|
軟骨形成不全,小預症
|
| ACE阻害薬
|
発育遅延,胎児死亡
|
| コカイン
|
発育遅延,小頭症,行動異常,腹壁破裂
|
| アルコール
|
胎児性アルコール症候群,短眼険裂,上顎骨発育不全,心臓,異常,精神発達遅滞
|
| イソトレチノイン(ビタミンA)
|
ビタミンA胚子病：小さい異常な形をした耳,下顎骨発育不全,口蓋裂,心臓異常
|
| 有機水銀
|
脳性麻痺類似の神経症状
|
| 鉛
|
発育遅延,神経学的障害
|
| ホルモン
|
男性化ホルモン(工チステロン,ノル工チステロン)
|
女性生殖器男性化：陰唇の癒着,陰核肥大
|
| ジエチルスチルベストロール(DES)
|
子宮,卵管,および腟上部の異常;腟癌;精巣異常
|
| 母親の糖尿病
|
さまざまな種類の異常;心臓と神経管の異常が最も一般的
|
[★]
- 関
- actual、actually、in fact、in practice、indeed、practically
[★]
- 関
- element、elementary、factorial、parameter
[★]
- 関
- teratogenesis、teratogenetic、teratogenicity