亜急性連合性脊髄変性症
WordNet
- work natural fibers into a thread; "spin silk"
- prolong or extend; "spin out a visit" (同)spin out
- the act of rotating rapidly; "he gave the crank a spin"; "it broke off after much twisting" (同)twirl, twist, twisting, whirl
- a distinctive interpretation (especially as used by politicians to sway public opinion); "the campaign put a favorable spin on the story"
- a short drive in a car; "he took the new car for a spin"
- a swift whirling motion (usually of a missile)
- revolve quickly and repeatedly around ones own axis; "The dervishes whirl around and around without getting dizzy" (同)spin around, whirl, reel, gyrate
- form a web by making a thread; "spiders spin a fine web"
- make up a story; "spin a yarn"
- stream in jets, of liquids; "The creek spun its course through the woods"
- twist and turn so as to give an intended interpretation; "The Presidents spokesmen had to spin the story to make it less embarrassing"
- a special situation; "this thing has got to end"; "it is a remarkable thing"
- a separate and self-contained entity
- an action; "how could you do such a thing?"
- an artifact; "how does this thing work?"
- an entity that is not named specifically; "I couldnt tell what the thing was"
- any attribute or quality considered as having its own existence; "the thing I like about her is ..."
- a persistent illogical feeling of desire or aversion; "he has a thing about seafood"; "she has a thing about him"
- a special abstraction; "a thing of the spirit"; "things of the heart"
- a special objective; "the thing is to stay in bounds"
- a statement regarded as an object; "to say the same thing in other terms"; "how can you say such a thing?"
- an event; "a funny thing happened on the way to the..."
- join for a common purpose or in a common action; "These forces combined with others"
- harvester that heads and threshes and cleans grain while moving across the field
- add together from different sources; "combine resources"
- stack in cords; "cord firewood"
- a unit of amount of wood cut for burning; 128 cubic feet
- a cut pile fabric with vertical ribs; usually made of cotton (同)corduroy
- a light insulated conductor for household use (同)electric cord
- a line made of twisted fibers or threads; "the bundle was tied with a cord"
- bind or tie with a cord
PrepTutorEJDIC
- (羊毛などから)〈糸など〉‘を'『紡ぐ』《+『名』+『out of』+『名』〈羊毛〉》,(糸などに)〈羊毛など〉‘を'紡ぐ《+『名』〈羊毛〉+『into』+『名』》 / 〈クモ・カイコなどが〉〈糸〉‘を'『吐く』;〈巣・繭〉‘を'かける / …‘を'くるくる回す / 〈物語など〉‘を'作る,話す / 『糸を紡ぐ』;〈クモ・カイコなどが〉糸を吐く / 〈こまなどが〉くるくる回る / 〈車などが〉疾走する / 〈頭などが〉くらくらする / 〈C〉〈U〉くるくる回すこと;回転 / 〈C〉《単数形で》(車などの)一走り / 〈C〉(飛行機の)きりもみ降下 / 〈C〉《単数形で》(価値などの)急落
- 〈C〉(形のある)『物』,物体;(生物に対しての)『無生物』 / 〈C〉(形のない)『もの』,事,事柄,でき事 / 《複数形で》事情,事態,状勢,状況 / 《複数形で》(すべての)事物,事柄 / 《通例 the~》(努力・活動などの)目的,目標 / 〈C〉衣服,衣類・《one's things》持ち物,所持品,身の回り品 / 《複数形で》道具,用具・〈C〉《親愛・哀れみ・軽べつなどの感情をこめて》人,者,やつ / 《the~》《話》(…の)流行《+in+名》
- …'を'『結合する』,合同する / …'を'兼ね備える;(…と)…'を'兼ね合わさせる《+『名』+『with』+『名』》 / …'を'化合させる;(…と)…'を'化合させる《+『名』+『with』+『名』》 / 『結合する』,連合する,合同する / (…と)化合する《+『with』+『名』》 / 連合,合同;(特に)企業合同,政治連合 / (また『combine harvester』)(刈り取りと脱穀が同時にできる)複式収穫機,コンバイン
- 〈U〉〈C〉『綱,ひも』(stringより太くropeより細い) / 〈U〉〈C〉束縛,きずな / 〈C〉〈U〉(電気の)『コード』,線 / (またchord)〈C〉(動物体の)索状組織,腱(けん) / 〈C〉うね織り,(特に)コールテン;(うね織りの)うね;《複数形で》コールテンのズボン / 〈C〉コード(材木の容積の単位で約6.25m) / …'を'綱(ひも)で縛る
- 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
UpToDate Contents
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English Journal
- Myelin damage due to local quantitative abnormalities in normal prion levels: evidence from subacute combined degeneration and multiple sclerosis.
- Scalabrino G1, Veber D.
- Journal of neurology.J Neurol.2014 Aug;261(8):1451-60. doi: 10.1007/s00415-013-7152-3. Epub 2013 Oct 20.
- Cobalamin (Cbl) deficiency causes an imbalance in some cytokines and growth factors in the central nervous system and peripheral nervous system (PNS) of the rat, and in the serum and cerebrospinal fluid (CSF) of adult Cbl-deficient (Cbl-D) patients. It is conceivable that this imbalance triggers sub
- PMID 24141733
- Prevalence of MR imaging abnormalities in vitamin B12 deficiency patients presenting with clinical features of subacute combined degeneration of the spinal cord.
- Jain KK1, Malhotra HS2, Garg RK2, Gupta PK2, Roy B1, Gupta RK3.
- Journal of the neurological sciences.J Neurol Sci.2014 Jul 15;342(1-2):162-6. doi: 10.1016/j.jns.2014.05.020. Epub 2014 May 15.
- BACKGROUND AND AIMS: Subacute combined degeneration (SACD) of the spinal cord, characterized by degeneration of lateral and posterior columns, is often found in vitamin B12 deficiency. Our aim was to look for sensitivity of imaging in depicting the spinal cord abnormality in vitamin B12 deficient pa
- PMID 24857760
- Central motor conduction studies in patients with spinal cord disorders: a review.
- Nardone R1, Höller Y2, Thomschewski A2, Höller P2, Bergmann J3, Golaszewski S4, Brigo F5, Trinka E2.
- Spinal cord.Spinal Cord.2014 Jun;52(6):420-7. doi: 10.1038/sc.2014.48. Epub 2014 Apr 22.
- STUDY DESIGN: Topical review of the literature.OBJECTIVES: The evaluation of patients with myelopathies requires radiological investigations; however, for the correct interpretation of the neuroimaging findings, the functional assessment of corticospinal conduction is helpful or even mandatory in ma
- PMID 24752292
Japanese Journal
- 多系統萎縮症に類似した多彩な中枢神経症状を呈し，免疫治療に反応した抗Ma2抗体陽性の1例
- ホモシスチン尿症をともなったメチルマロン酸尿症の1例
- ビタミンB群および関連物質と臨床(<特集>「ビタミン誘導体の臨床応用」(第64回大会シンポジウム))
Related Links
- Causes Subacute combined degeneration of the spinal cord is caused by a vitamin B12 deficiency. (For specific information on vitamin B12 deficiency, see the article on pernicious anemia.) Subacute combined ...
- subacute combined degeneration of spinal cord（SCDC） 「概念」 VitB12欠乏により、脊髄が変性するもの。 ちなみに、連合性とは、側索＋後索のこと。 「病理」 脊髄（側索＋後索）が変性する 。 「参考」（側索＋後索） ① ② ...
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- 英
- subacute combined degeneration of spinal cord, subacute combined degeneration of the spinal cord, SCDC
- 同
- 後索側索硬化症 posterolateral sclerosis、subacute combined degeneration of the dorsal (posterior) and lateral spinal columns (uptodate)
- 関
- ビタミンB12、subacute combined degeneration？
[show details]
病因
- メカニズムは不明であるがミエリンの形成に異常が生じる (参考1)
病理
- 脊髄後索と側索の脱髄・変性
- 大脳白質・末梢神経にも髄鞘の脱髄と軸索の変性が起こる。軸索の変性は軽度。
病態
- 錐体路徴候、深部感覚障害・運動失調(BET.156)
- 初発症状は感覚異常と深部感覚の異常であり、重度の脱力、痙性(spasticity)、痙縮(clonus)、麻痺、さらに便失禁・便失禁をきたすことがある。(参考1)
- 下肢遠位部が優位となる。
- 1) 後索症状：感覚障害(特に深部感覚)、後索性失調、ロンベルク徴候
- 2) 錐体路徴候：痙性対麻痺、膝蓋腱反射亢進、バビンスキー徴候
- 3) 末梢神経の脱髄(参考1)：四肢末梢の痺れ、痛み、深部腱反射消失
- 4) 中枢神経症状(記憶喪失、易刺激性、および認知症)(参考1)
病因
検査
- 画像は参考3より引用
診断
- 症候と検査(血中ビタミンB12、シリングテスト)により診断
治療
参考
- http://www.nurs.or.jp/~academy/igaku/s7/s75182.htm
- . [charged] Etiology and clinical manifestations of vitamin B12 and folic acid deficiency - uptodate [1]
- 3. Anitha Sen et al;Ann Indian Acad Neurol 2013 Apr;16(2):255-8. Spinal MR Imaging in Vitamin B12 Deficiency: Case Series; Differential Diagnosis of Symmetrical Posterior Spinal Cord Lesions
- https://pubmed.ncbi.nlm.nih.gov/23956577/
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- 関
- ally、associate、bind、binding、bond、bonding、combination、combined application、complicate、concomitant、concurrent、conjoin、conjugate、conjugation、conjunction、connect、connection、couple、dock、engage、engagement、join、ligate、linkage、merge、merger、symphysial、union
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- 関
- degeneracy、degenerate、degenerative、denaturation、denature、involution、retract、retrograde degeneration、retrograde degradation、unfolding
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- 関
- chorda、chordae、chordal、code、tendon、trabecula、trabeculae
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- 関
- dorsal spine、rachis、spinal column、spinal cord、spine、vertebral column
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- 関
- (n.)precordia 前胸部、(adj.)precordial 前胸部の