WordNet

lack of success; "he felt that his entire life had been a failure"; "that year there was a crop failure"
loss of ability to function normally; "kidney failure"
an act that fails; "his failure to pass the test"
an unexpected omission; "he resented my failure to return his call"; "the mechanics failure to check the brakes"
a person with a record of failing; someone who loses consistently (同)loser, nonstarter, unsuccessful person
an event that does not accomplish its intended purpose; "the surprise party was a complete failure"

PrepTutorEJDIC

〈U〉(…における)『失敗』,不成功《+『in』+『名』(do『ing』)》 / 〈C〉失敗者,落後者;失敗した企て,不できなもの / 〈U〉〈C〉怠慢,不履行 / 〈U〉〈C〉(…の)不足,欠乏《+『of』+『名』》 / 〈U〉〈C〉(…の)破産《+『of』+『名』》 / 〈U〉(…の)『衰弱』,減退《+『in』(『of』+『名』》

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 心不全におけるACE阻害剤の腎効果 renal effects of ace inhibitors in heart failure
2. 心不全の予後 prognosis of heart failure
3. 収縮能障害による心不全の治療の概要 overview of the therapy of heart failure due to systolic dysfunction
4. 収縮能障害による心不全におけるβブロッカー使用の理論的根拠および臨床試験 rationale for and clinical trials of beta blockers in heart failure due to systolic dysfunction
5. 拡張期心不全の臨床症状および診断 clinical manifestations and diagnosis of diastolic heart failure

Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula.

Červenka L1,2, Melenovský V3, Husková Z1, Škaroupková P1, Nishiyama A4, Sadowski J5.
Clinical and experimental pharmacology & physiology.Clin Exp Pharmacol Physiol.2015 Jul;42(7):795-807. doi: 10.1111/1440-1681.12419.
The detailed mechanisms determining the course of congestive heart failure (CHF) in hypertensive subjects with associated renal dysfunction remain unclear. In Ren-2 transgenic rats (TGR), a model of angiotensin II (ANG II)-dependent hypertension, CHF was induced by volume overload achieved by creati
PMID 25969338

A Salt-Induced Reno-Cerebral Reflex Activates Renin-Angiotensin Systems and Promotes CKD Progression.

Cao W1, Li A1, Wang L1, Zhou Z1, Su Z1, Bin W1, Wilcox CS2, Hou FF3.
Journal of the American Society of Nephrology : JASN.J Am Soc Nephrol.2015 Jul;26(7):1619-33. doi: 10.1681/ASN.2014050518. Epub 2015 Jan 29.
Salt intake promotes progression of CKD by uncertain mechanisms. We hypothesized that a salt-induced reno-cerebral reflex activates a renin-angiotensin axis to promote CKD. Sham-operated and 5/6-nephrectomized rats received a normal-salt (0.4%), low-salt (0.02%), or high-salt (4%) diet for 2 weeks.
PMID 25635129

Endogenous Toll-Like Receptor 9 Regulates AKI by Promoting Regulatory T Cell Recruitment.

Alikhan MA1, Summers SA2, Gan PY1, Chan AJ1, Khouri MB1, Ooi JD1, Ghali JR2, Odobasic D1, Hickey MJ1, Kitching AR3, Holdsworth SR4.
Journal of the American Society of Nephrology : JASN.J Am Soc Nephrol.2015 Jun 26. pii: ASN.2014090927. [Epub ahead of print]
Toll-like receptor 9 (TLR9) enhances proinflammatory responses, but whether it can act in a regulatory capacity remains to be established. In experimental murine AKI induced by cisplatin, Tlr9-/- mice developed enhanced renal injury and exhibited fewer intrarenal regulatory T cells (Tregs) compared
PMID 26116356