WordNet
- the 19th letter of the Roman alphabet (同)s
PrepTutorEJDIC
- sulfurの化学記号 / {略}South[ern]
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/12/09 16:33:08」(JST)
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- 1. 黒色腫（メラノーマ）における所属リンパ節の病理学的評価 pathologic evaluation of regional lymph nodes in melanoma
- 2. 2型糖尿病の治療のためのジペプチジルペプチダーゼ4（DPP-4）阻害剤 dipeptidyl peptidase 4 dpp 4 inhibitors for the treatment of type 2 diabetes mellitus
- 3. 頸動脈内膜剥離術および頸動脈ステント留置術の麻酔 anesthesia for carotid endarterectomy and carotid stenting
- 4. 静脈血栓塞栓症の患者における理論的根拠と無期限の抗凝固の適応 rationale and indications for indefinite anticoagulation in patients with venous thromboembolism
- 5. 腹部大動脈瘤ステントグラフト留置術に対する麻酔 anesthesia for endovascular aortic repair
English Journal
- Unusual calcifying fibrous tumor in the fallopian tube: review and discussion of the differential diagnosis.
- Xiao P, Peng JJ, Li Y, Tian XY, Li B, Li Z.Author information Departments of Pathology (P.X., Y.L., B.L., Z.L.) Surgery (J.-J.P.), The First Affiliated Hospital, Sun Yet-sen University, Guangzhou School of Chinese Medicine (X.-Y.T.), Hong Kong Baptist University, Hong Kong, China.AbstractCalcifying fibrous tumor (CFT) is a rare benign soft tissue tumor of unknown etiology and extremely rare in female reproductive system. We present a case of unusual CFT in the ampulla of fallopian tube occurring in a middle-aged female patient with multiple uterine leiomyomas. A hysterectomy was performed on a 48-year-old woman for uterine leiomyomas. At surgery, a solitary, well-defined nodule, measuring 1.0 cm in diameter, was incidentally observed on the wall of ampulla of right fallopian tube. The lesion of fallopian tube was resected totally. Histologically, this lesion was unencapsulated and composed of hyalinized collagenous fibrous tissue with psammomatous calcification and focal lymphoplasmacytic infiltrate. Sparsely fibroblast-like spindle cells were scattered in the dense hyalinized background with bland nuclei. By immunohistochemistry, vimentin was diffusely positive in most cells, and a focal reactivity for CD34 was also observed in spindle cells. However, they were negative for cytokeratin (AE1/AE3), S-100 protein, CD117, DOG1, SMA, desmin, and ALK. The Ki-67 labeling index of the lesion was <1%. A diagnosis of primary CFT of fallopian tube was made. To our knowledge, this is the first report of CFT occurring in female reproductive tract. Awareness of CFT and its distinctive features is important to avoid a diagnostic pitfall caused by histologic similarities to other spindle cell or calcifying lesions in unusual locations. Although marginal excision is usually adequate for most of CFT, long-term follow-up is suggested as delayed recurrence might occur infrequently.
- International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.Int J Gynecol Pathol.2014 Jan;33(1):40-4. doi: 10.1097/PGP.0b013e31827c637c.
- Calcifying fibrous tumor (CFT) is a rare benign soft tissue tumor of unknown etiology and extremely rare in female reproductive system. We present a case of unusual CFT in the ampulla of fallopian tube occurring in a middle-aged female patient with multiple uterine leiomyomas. A hysterectomy was per
- PMID 24300534
- The Importance of Wound Biopsy in the Accurate Diagnosis of Acral Malignant Melanoma Presenting as a Foot Ulcer.
- Yin NC, Miteva M, Covington DS, Romanelli P, Stojadinovic O.Author information 1University of Miami Miller School of Medicine, Miami, FL, USA.AbstractNeoplastic changes arising at the sites of chronic, nonhealing wounds are not uncommon; however, they often go undiagnosed. We report a case of rapidly progressing plantar melanoma presenting as a chronic, nonhealing ulcer. A 46-year-old patient presented at a specialized Wound Healing Center with an enlarging painful ulcer on the right heel of 3 months duration. The wound was biopsied and specimens were sent for examination at the Wound Pathology service at the Department of Dermatology and Cutaneous Surgery, University of Miami. Histology demonstrated features consistent with acral malignant melanoma. Immunohistochemistry using melanocytic markers MART-1, S-100, HMB-45 revealed positive staining indicating the presence of malignant cells, and D2-40 staining showed lymphatic invasion of the tumor in the wound biopsy specimen. The case presented here underscores the importance of wound biopsying in the diagnosis of malignancies associated with nonhealing wounds.
- The international journal of lower extremity wounds.Int J Low Extrem Wounds.2013 Dec 9. [Epub ahead of print]
- Neoplastic changes arising at the sites of chronic, nonhealing wounds are not uncommon; however, they often go undiagnosed. We report a case of rapidly progressing plantar melanoma presenting as a chronic, nonhealing ulcer. A 46-year-old patient presented at a specialized Wound Healing Center with a
- PMID 24323391
- Krüppel-Like Factor 6 Rendered Rat Schwann Cell More Sensitive to Apoptosis via Upregulating FAS Expression.
- Gui T, Wang Y, Zhang L, Wang W, Zhu H, Ding W.Author information Department of Anatomy, Shanghai Jiao Tong University School of Medicine, Shanghai, China.AbstractKrüppel-like factor 6 (KLF6) is a tumor suppressor gene and play a role in the regulation of cell proliferation and apoptosis. After the peripheral nerve injury (PNI), the microenvironment created by surrounding Schwann cells (SCs) is a critical determinant of its regenerative potential. In this study, we examined the effects of KLF6 on SCs responses during PNI. Both KLF6 mRNA and protein expression levels were upregulated in the injured sciatic nerve, and immunofluorescence results showed that many KLF6-positive cells simultaneously expressed the SC markers S-100 and p75NTR. The apoptosis inducers TNFα and cisplatin upregulated KLF6 expression in primary cultured SCs and the SC line RSC96. Although KLF6 overexpression exacerbated cisplatin- and TNFα-induced apoptosis, expression levels of the apoptosis regulators Bcl2 and Bax were not significantly affected in either KLF6-overexpressing or KLF6-depleted RSC96 cells. Realtime PCR arrays and qRT-PCR demonstrated that KLF6 overexpression upregulated four pro-apoptotic genes, FAS, TNF, TNFSF12, and PYCARD, and inhibited expression of the anti-apoptotic IL10 gene expression. Further analysis revealed that FAS protein expression was positively correlated with KLF6 expression in SCs. These data suggest that KLF6 upregulation may render SCs more vulnerable to apoptosis after injury via upregulating FAS expression.
- PloS one.PLoS One.2013 Dec 4;8(12):e82449. doi: 10.1371/journal.pone.0082449.
- Krüppel-like factor 6 (KLF6) is a tumor suppressor gene and play a role in the regulation of cell proliferation and apoptosis. After the peripheral nerve injury (PNI), the microenvironment created by surrounding Schwann cells (SCs) is a critical determinant of its regenerative potential. In this st
- PMID 24324791
Japanese Journal
- No Oncogenic Role for WT1 in Peripheral Nerve Sheath Tumors (Originals)
- Jikeikai medical journal 58(4), 95-102, 2011-12-10
- NAID 120003753068
- 炎症薬理学とがん転移
- 丸 義朗
- 日本薬理學雜誌 = Folia pharmacologica Japonica 138(4), 155-160, 2011-10-01
- … の恒常性維持に関与している分子プログラムが原発巣によって質的・量的変化を受けた結果であると考えている．具体的には，肺転移の場合，原発巣の産生するVEGFやTNFαによって転移臓器である肺で遊走因子S100A8やSAA3の発現が亢進する．両者は病原体センサーTLR4の内因性アゴニストであり，TLR4を発現している骨髄球系細胞やがん細胞を肺に動員させる．肺に特異的に発現し，正常状態でも間断なく到来する気道由来 …
- NAID 10029767938
Related Links
- PowerShot PowerShot S PowerShot S100 [ブラック] 映像エンジン「DIGIC 5」や光学5倍ズームレンズを搭載したコンパクトデジタルカメラ 他の色を見る ショップが販売価格を掲載するまでお待ちください お気に入り製品に登録すると、価格が ...
- We are not selling antibodies. / Nous ne vendons pas d'anticorps. / Wir verkaufen keinen Antikorper. No vendemos un anticuerpo. / 我們沒銷售抗體 / мы ... Anti-抗体名 略称 別名 HOST CLONE名 適用 Human S-100 protein S100p
Related Pictures
★リンクテーブル★
| リンク元 | 「粘膜下腫瘍」「消化管カルチノイド」「ランゲルハンス細胞」 |
| 拡張検索 | 「S-100蛋白」 |
| 関連記事 | 「S」 |
「粘膜下腫瘍」
概念
- 主病変が粘膜下層以下に存在する隆起病変の総称
分類
胃
- 非上皮病変
- 上皮性病変
- 迷入膵
- 嚢胞
- カルチノイド
- 炎症性病変
形態的特徴
- Delle デレ
- なだらかな陰影の移行(造影、X線透視)、なだらかな隆起の移行(内視鏡)
- bridging fold(ヒダが腫瘤をよけない)
- 粘膜表面に異常は認められない(圧排が強くなれば何らかの影響はある、と思う)
参考
- 1.
「消化管カルチノイド」
病理
- 好銀反応：陽性
- 免疫組織化学：NSE(+)、S-100蛋白(+)、クロモグラニン染色(+)
例外
- 直腸カルチノイド：好銀反応(-)、argentaffin反応(-)、セロトニン産生(-)
病態
- 好発部位：直腸(最も多い)、虫垂、胃、十二指腸
治療
- 直径1cm以下：内視鏡下粘膜切除術、筋層を含む局所切除術
- 直径2cm以上：(転移率が高い)リンパ節郭清を伴う根治術、肝線維走の切除
参考
- 1. 消化管カルチノイドのエビデンスデータ
- 2. がん情報サイト｜PDQ®日本語版(医療専門家向け)
「ランゲルハンス細胞」
- 英
- Langerhans cell, Langerhans cells
- 同
- Langerhans細胞
- 関
- [[]]
- 骨髄由来の樹状細胞
- 抗原提示能あり
- 有棘層に存在
- 紫外線放射により機能が抑制される。ステロイドによりランゲルハンス細胞の数が減る
- 気道粘膜上にも存在する？
- 表皮、食道粘膜以外の骨髄由来の抗原提示細胞であって、ランゲルハンス細胞と同じと考えられる細胞は樹状細胞とよばれる？
組織学
- 細胞質内に特徴的なランゲルハンス細胞顆粒(バーベック顆粒)
細胞マーカー
臨床関連
「S-100蛋白」
- 英
- S100 protein
- 同
- S-100タンパク、S100蛋白質、S-100
- 関
- [[]]
- 悪性黒色腫のマーカー
- 下垂体前葉の嫌色素性細胞である folliculostellate cell
「S」