Ca2+-induced Ca2+ release

• カルシウム誘発カルシウム遊離、Ca2+誘発Ca2+遊離

関

calcium-induced calcium release、CICR

同

CICR

WordNet

1. part with a possession or right; "I am relinquishing my bedroom to the long-term house guest"; "resign a claim to the throne" (同)relinquish, resign, free, give_up
2. a process that liberates or discharges something; "there was a sudden release of oxygen"; "the release of iodine from the thyroid gland"
3. a device that when pressed will release part of a mechanism (同)button
4. activity that frees or expresses creative energy or emotion; "she had no other outlet for her feelings"; "he gave vent to his anger" (同)outlet, vent
5. (music) the act or manner of terminating a musical phrase or tone (同)tone ending
6. a formal written statement of relinquishment (同)waiver, discharge
7. merchandise issued for sale or public showing (especially a record or film); "a new release from the London Symphony Orchestra"
8. release (gas or energy) as a result of a chemical reaction or physical decomposition (同)free, liberate
9. reason or establish by induction
10. cause to arise; "induce a crisis" (同)bring_on
11. produce electric current by electrostatic or magnetic processes (同)induct
12. cause to do; cause to act in a specified manner; "The ads induced me to buy a VCR"; "My children finally got me to buy a computer"; "My wife made me buy a new sofa" (同)stimulate, cause, have, get, make
13. cause to occur rapidly; "the infection precipitated a high fever and allergic reactions" (同)stimulate, rush, hasten
14. the 3rd letter of the Roman alphabet (同)c
15. (music) the keynote of the scale of C major
16. a general-purpose programing language closely associated with the UNIX operating system
17. brought about or caused; not spontaneous; "a case of steroid-induced weakness"

PrepTutorEJDIC

1. (束縛・義務などから)〈人・動物など〉‘を'『自由にする』,解放する《+『名』+『from』+『名』》 / 〈矢など〉‘を'放つ,〈爆弾〉‘を'投下する;〈締めつけた物〉‘を'ゆるめて放す / 〈ニュースなど〉‘を'発表する;〈レコード・書籍など〉‘を'発売する,〈映画〉‘を'封切りする / (人に)〈権利など〉‘を'譲渡する《+『名』+『to』+『名』》 / (束縛・義務などからの)『解放』,放免,免除《+『from』+『名』》 / (ガスなどの)放出;(爆弾の)投下;(感情の)吐露《+『of』(『to』)+『名』》 / (ニュースなどの)発表;(映画などの)封切り,(レコードなどの)発表 / (機械の)作動装置,レリーズ
2. 〈人〉‘に'『勧めて』(…)『させる』 / …‘を'『引き起こす』,もたらす(cause) / 〈電気〉‘を'誘導する / …‘を'帰納する
3. carbonの化学記号
4. Calciumの化学記号

UpToDate Contents

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English Journal

• Excess TGF-β mediates muscle weakness associated with bone metastases in mice.

• Waning DL1, Mohammad KS1, Reiken S2, Xie W2, Andersson DC2, John S1, Chiechi A1, Wright LE1, Umanskaya A2, Niewolna M1, Trivedi T1, Charkhzarrin S1, Khatiwada P1, Wronska A2, Haynes A2, Benassi MS3, Witzmann FA4, Zhen G5, Wang X5, Cao X5, Roodman GD6,7, Marks AR2, Guise TA1.
• Nature medicine.Nat Med.2015 Oct 12. doi: 10.1038/nm.3961. [Epub ahead of print]
• Cancer-associated muscle weakness is a poorly understood phenomenon, and there is no effective treatment. Here we find that seven different mouse models of human osteolytic bone metastases-representing breast, lung and prostate cancers, as well as multiple myeloma-exhibited impaired muscle function,
• PMID 26457758

• Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells.

• Pratt EP1, Salyer AE2, Guerra ML2, Hockerman GH3.
• Molecular and cellular endocrinology.Mol Cell Endocrinol.2015 Oct 3. pii: S0303-7207(15)30100-3. doi: 10.1016/j.mce.2015.09.034. [Epub ahead of print]
• We previously reported that INS-1 cells expressing the intracellular II-III loop of the L-type Ca2+ channel Cav1.2 (Cav1.2/II-III cells) are deficient in Ca2+-induced Ca2+ release (CICR). Here we show that glucose-stimulated ERK 1/2 phosphorylation (GSEP) is slowed and reduced in Cav1.2/II-III cells
• PMID 26435461

• Rad and Rem are non-canonical G-proteins with respect to the regulatory role of guanine nucleotide binding in CaV 1.2 regulation.

• Chang DD1, Colecraft HM1.
• The Journal of physiology.J Physiol.2015 Oct 1. doi: 10.1113/JP270889. [Epub ahead of print]
• Rad and Rem are Ras-like G-proteins linked to diverse cardiovascular functions and patho-physiology. Understanding how Rad and Rem are regulated is important for deepened insights into their patho-physiological roles. Like other Ras-like G-proteins, Rad and Rem contain a conserved guanine-nucleotide
• PMID 26426338

Japanese Journal

• Nitric oxide-induced calcium release: activation of type 1 ryanodine receptor by endogenous nitric oxide.

• Kakizawa Sho,Yamazawa Toshiko,Iino Masamitsu
• Channels 7(1), 1-5, 2013-01-01
• … Ryanodine receptors (RyRs), located in the sarcoplasmic/endoplasmic reticulum (SR/ER) membrane, are required for intracellular Ca2+ release that is involved in a wide range of cellular functions. …
• NAID 120005333788

• Fetal and Neonatal Development of Ca^<2+> Transients and Functional Sarcoplasmic Reticulum in Beating Mouse Hearts

• KAWAMURA Yoichi,ISHIWATA Takahiro,TAKIZAWA Mari,ISHIDA Hideyuki,ASANO Yuh,NONOYAMA Shigeaki
• Circulation journal : official journal of the Japanese Circulation Society 74(7), 1442-1450, 2010-06-25
• … Background: It is generally accepted that Ca2+-induced Ca2+ release is not the predominant mechanism during embryonic stages. … The aim of the present study was to investigate developmental changes in Ca2+ transients using whole hearts of mouse embryos and neonates. … Methods and Results: Fluo-3 fluorescence signals from stimulated whole hearts were detected using a photomultiplier and stored as Ca2+ transients. …
• NAID 10030695829

• From the Ryanodine Receptor to Cardiac Arrhythmias

• EISNER D. A.,KASHIMURA T.,VENETUCCI L. A.,TRAFFORD A. W.
• Circulation journal : official journal of the Japanese Circulation Society 73(9), 1561-1567, 2009-08-20
• … Cardiac contraction is activated by an increase of intracellular calcium concentration ([Ca2+]i), most of which comes from the sarcoplasmic reticulum (SR) where it is released, via the ryanodine receptor (RyR), in response to Ca2+ entering the cell on the L-type Ca2+ current. … This phenomenon is termed Ca2+-induced Ca2+ release (CICR). …
• NAID 10025934322

Related Links

• Ca2+-induced Ca2+ Release in Sensory Neurons - ResearchGate

ABSTRACT Ca2+-induced Ca2+ release (CICR) is a ubiquitous mechanism by which Ca2+ release from the endoplasmic reticulum amplifies the trigger Ca2+ entry and generates propagating Ca2+ waves. To elucidate the ...

• T-tubule depolarization-induced SR Ca2+ release is controlled ...

In vertebrate skeletal muscle, the voltage-dependent mechanism of rapid sarcoplasmic reticulum (SR) Ca2+ release, commonly referred to as excitation-contraction (EC) coupling, is believed to be mediated by physical interaction ...

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★リンクテーブル★

関連記事	「induce」「C」「induced」「release」「Ca」

「induce」

　　[★]

• v.

• 誘発する、誘導する、誘起する、導入する、引き起こす

関

cause、challenge、derivation、elicit、elicitation、evocation、evoke、guidance、induction、inductive、introduce、introduction、precipitate、provocation、provoke、spark

　 　 　 　 　 　

「C」

　　[★]

• 炭素 carbon
• シトシン cytosine
• システイン cysteine
• シチジン
• セルシウス度 摂氏 degrees Celsius degree C
• 産婦人科領域で「子宮外頚 子宮外頚部 exocervix」を表現するための略語

　 　 　 　

「induced」

　　[★]

• v.

• (induceの過去分詞)誘導される、引き起こされる

hypercalcaemia induced pancreatitis 高カルシウム血症による膵炎

　

「release」

　　[★]

• n.

• 遊離、放出、リリース、

• v.

• 遊離する、放出する

　 　 　 　 　 　 　 　 　

「Ca」

　　[★] カルシウム calcium