- 関
- long-chain acyl-CoA dehydrogenase、VLCAD
- 同
- VLCAD
WordNet
- primarily temporal sense; being or indicating a relatively great or greater than average duration or passage of time or a duration as specified; "a long life"; "a long boring speech"; "a long time"; "a long friendship"; "a long game"; "long ago"; "an hour long"
- (of speech sounds or syllables) of relatively long duration; "the English vowel sounds in `bate, `beat, `bite, `boat, `boot are long"
- for an extended distance
- for an extended time or at a distant time; "a promotion long overdue"; "something long hoped for"; "his name has long been forgotten"; "talked all night long"; "how long will you be gone?"; "arrived long before he was expected"; "it is long after your bedtime"
- having or being more than normal or necessary:"long on brains"; "in long supply"
- holding securities or commodities in expectation of a rise in prices; "is long on coffee"; "a long position in gold"
- involving substantial risk; "long odds"
- of relatively great height; "a race of long gaunt men"- Sherwood Anderson; "looked out the long French windows"
- primarily spatial sense; of relatively great or greater than average spatial extension or extension as specified; "a long road"; "a long distance"; "contained many long words"; "ten miles long"
- fasten or secure with chains; "Chain the chairs together"
- a unit of length
- a necklace made by a stringing objects together; "a string of beads"; "a strand of pearls"; (同)string, strand
- a linked or connected series of objects; "a chain of daisies"
- a series of (usually metal) rings or links fitted into one another to make a flexible ligament
- anything that acts as a restraint
- (chemistry) a series of linked atoms (generally in an organic molecule) (同)chemical chain
- a series of things depending on each other as if linked together; "the chain of command"; "a complicated concatenation of circumstances" (同)concatenation
- (business) a number of similar establishments (stores or restaurants or banks or hotels or theaters) under one ownership
- connect or arrange into a chain by linking
- precisely so; "on the very next page"; "he expected the very opposite"
- used as intensifiers; `real is sometimes used informally for `really; `rattling is informal; "she was very gifted"; "he played very well"; "a really enjoyable evening"; "Im real sorry about it"; "a rattling good yarn" (同)really, real, rattling
- precisely as stated; "the very center of town"
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- prolonged unfulfilled desire or need (同)yearning, hungriness
PrepTutorEJDIC
- (距離・物の長さが)『長い』 / (時間が)『長い』,長く続く / 《時間・距離などを表離などを表す語を伴って》長さが…の / 『長々しい』,あきあきする / (数量が標準よりも)『多い』,長い / (人が)やせてひょろ長い / 長く,長い間,久しく / …じゅう / ずっと(前に,後に) / 長い間
- 『熱望する』
- 『鎖』;(装飾用の)鎖 / 《複数形で》『束縛』,拘束;囚人をつなぐ鎖 / (物事の)『連続』,つながり《+『of』+『名』》 / (商店・銀行・ホテルなどの)チェーン(一連の店が同一資本のもとで連携して経営される方式;その店) / チェーン(測量で用いられる単位;約21.7m) / …'を'『鎖でつなぐ』《+『up』(『together』)+『名,』+『名』+『up』(『together』)》
- 《副詞・形容詞・分詞形容詞を強めて》『非常に』,とても,たいへん,きわめて / 《否定語と共に用いて》『あまり』,さほど,たいして(…でない) / 《same, opposite, [one's]ownなどの前で》『真に,まったく』,ほんとうに / 《古》まったくの,本物の,真の / 《the(this,that,one's)~》『まさにその』,ちょうどその / 《the(one's)~》ただ…だけで(mere);(…)でさえ,までも(even)
- carbonの化学記号
- 『あこがれ』,熱望 / (目の表情などが)あこがれの,熱望している
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/08/14 10:21:57」(JST)
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Very-long-chain acyl-CoA dehydrogenase |
Identifiers |
EC number |
1.3.8.9 |
Databases |
IntEnz |
IntEnz view |
BRENDA |
BRENDA entry |
ExPASy |
NiceZyme view |
KEGG |
KEGG entry |
MetaCyc |
metabolic pathway |
PRIAM |
profile |
PDB structures |
RCSB PDB PDBe PDBsum |
Search |
PMC |
articles |
PubMed |
articles |
NCBI |
proteins |
|
Very-long-chain acyl-CoA dehydrogenase (EC 1.3.8.9, ACADVL (gene).) is an enzyme with system name very-long-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction
- a very-long-chain acyl-CoA + electron-transfer flavoprotein a very-long-chain trans-2,3-dehydroacyl-CoA + reduced electron-transfer flavoprotein
This enzyme contains FAD as prosthetic group.
References
- ^ Izai, K., Uchida, Y., Orii, T., Yamamoto, S. and Hashimoto, T. (1992). "Novel fatty acid β-oxidation enzymes in rat liver mitochondria. I. Purification and properties of very-long-chain acyl-coenzyme A dehydrogenase". J. Biol. Chem. 267 (2): 1027–1033. PMID 1730632.
- ^ Aoyama, T., Souri, M., Ushikubo, S., Kamijo, T., Yamaguchi, S., Kelley, R.I., Rhead, W.J., Uetake, K., Tanaka, K. and Hashimoto, T. (1995). "Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients". J. Clin. Invest. 95 (6): 2465–2473. doi:10.1172/JCI117947. PMC 295925. PMID 7769092.
- ^ McAndrew, R.P., Wang, Y., Mohsen, A.W., He, M., Vockley, J. and Kim, J.J. (2008). "Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase". J. Biol. Chem. 283 (14): 9435–9443. doi:10.1074/jbc.M709135200. PMC 2431035. PMID 18227065.
External links
- Very-long-chain acyl-CoA dehydrogenase at the US National Library of Medicine Medical Subject Headings (MeSH)
UpToDate Contents
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English Journal
- Role of suppressor of cytokine signaling 3 in lipid metabolism: Analysis based on a phage-display human liver cDNA library.
- Luo B, Zou T, Lu N, Chai F, Ye X, Wang Y, Qi Y.SourceState Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, People's Republic of China.
- Biochemical and biophysical research communications.Biochem Biophys Res Commun.2011 Dec 9;416(1-2):39-44. Epub 2011 Nov 11.
- Suppressor of cytokine signaling 3 (SOCS3) is a likely mediator of feedback inhibition on the leptin receptor and may cause physiological leptin-resistance, leading to the development of obesity. The aim of this study was to identify potential peptides interacting with purified SOCS3 by using a phag
- PMID 22093833
- Dexamethasone facilitates lipid accumulation in chicken skeletal muscle.
- Wang XJ, Song ZG, Jiao HC, Lin H.SourceDepartment of Animal Science, Shandong Agricultural University , Taian, Shandong 271018 , P.R. China.
- Stress (Amsterdam, Netherlands).Stress.2011 Dec 7. [Epub ahead of print]
- The effects of glucocorticoid on lipid metabolism of broiler chicken (Gallus gallus domesticus) skeletal muscle were investigated. Male Arbor Acres chickens (35 days old) were subjected to dexamethasone treatment for 3 days. We found that dexamethasone retards body growth while facilitating lipid ac
- PMID 22085283
Japanese Journal
- 臨床研究・症例報告 反復する横紋筋融解症を契機に診断に至った極長鎖アシルCoA脱水素酵素欠損症の1例
- 極長鎖アシルCoA脱水素酵素(VLCAD)欠損症の22歳女性例に対する食事療法の試み
- 春木 明代,川井 元晴,小笠原 淳一 [他],古賀 道明,根来 清,神田 隆
- 臨床神経学 50(3), 172-174, 2010-03-01
- NAID 10026291634
- Development of a New Enzymatic Diagnosis Method for Very-long-chain Acyl-CoA Dehydrogenase Deficiency by Detecting 2-Hexadecenoyl-CoA Production and its Application in Tandem Mass Spectrometry-based Selective Screening and Newborn Screening in Japan
- Tajima Go,Sakura Nobuo,Shirao Kenichiro,Okada Satoshi,Tsumura Miyuki,Nishimura Yutaka,Ono Hiroaki,Hasegawa Yuki,Hata Ikue,Naito Etsuo,Yamaguchi Sew,Shigematsu Yosuke,Kobayashi Masao
- PEDIATRIC RESEARCH 64(6), 667-672, 2008-00-00
- NAID 120004687668
Related Links
- Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency is a condition that prevents the body from converting certain ... Gene Review: Very Long Chain Acyl- Coenzyme A Dehydrogenase Deficiency This link leads to a site outside Genetics ...
Related Pictures
★リンクテーブル★
[★]
- 英
- very-long-chain acyl-CoA dehydrogenase、VLCAD
- 関
- 長鎖アシルCoA脱水素酵素、超長鎖アシルCoA脱水素酵素
[★]
- 英
- very-long-chain acyl-CoA dehydrogenase
- 関
- 長鎖アシルCoA脱水素酵素、極長鎖アシルCoA脱水素酵素
[★]
- 関
- long-chain acyl-CoA dehydrogenase、very-long-chain acyl-CoA dehydrogenase
[★]
- 関
- LCAD、very-long-chain acyl-CoA dehydrogenase、VLCAD
[★]
極長鎖アシルCoA脱水素酵素欠損症
[★]
[★]
- 関
- enormously、exceedingly、extraordinarily、extremely、greatly、immensely、much、profoundly、super、supra、too、tremendously、ultra、vastly
[★]
- 関
- open-chain、strand
[★]
長い、望む
- 関
- desire、hope、lengthy、wish
[★]