telomere end-binding protein

• テロメア末端結合タンパク質

関

telomere-binding protein

WordNet

1. put an end to; "The terrible news ended our hopes that he had survived"
2. a final state; "he came to a bad end"; "the so-called glorious experiment came to an inglorious end" (同)destruction, death
3. the point in time at which something ends; "the end of the year"; "the ending of warranty period" (同)ending
4. bring to an end or halt; "She ended their friendship when she found out that he had once been convicted of a crime"; "The attack on Poland terminated the relatively peaceful period after WW I" (同)terminate
5. a piece of cloth that is left over after the rest has been used or sold (同)remainder, remnant, oddment
6. (American football) a position on the line of scrimmage; "no one wanted to play end"
7. the part you are expected to play; "he held up his end"
8. the concluding parts of an event or occurrence; "the end was exciting"; "I had to miss the last of the movie" (同)last, final_stage
9. either extremity of something that has length; "the end of the pier"; "she knotted the end of the thread"; "they rode to the end of the line"; "the terminals of the anterior arches of the fornix" (同)terminal
10. (football) the person who plays at one end of the line of scrimmage; "the end managed to hold onto the pass"
11. a boundary marking the extremities of something; "the end of town"
12. a final part or section; "we have given it at the end of the section since it involves the calculus"; "Start at the beginning and go on until you come to the end"
13. one of two places from which people are communicating to each other; "the phone rang at the other end"; "both ends wrote at the same time"
14. the surface at either extremity of a three-dimensional object; "one end of the box was marked `This side up"
15. have an end, in a temporal, spatial, or quantitative sense; either spatial or metaphorical; "the bronchioles terminate in a capillary bed"; "Your rights stop where you infringe upon the rights of other"; "My property ends by the bushes"; "The symphony ends in a pianissimo" (同)stop, finish, terminate, cease
16. be the end of; be the last or concluding part of; "This sad scene ended the movie" (同)terminate
17. executed with proper legal authority; "a binding contract"
18. the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
19. strip sewn over or along an edge for reinforcement or decoration
20. the capacity to attract and hold something
21. event whose occurrence ends something; "his death marked the ending of an era"; "when these final episodes are broadcast it will be the finish of the show" (同)conclusion, finish
22. the end of a word (a suffix or inflectional ending or final morpheme); "I dont like words that have -ism as an ending" (同)termination
23. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
24. either (free) end of a eukaryotic chromosome; "telomeres act as caps to keep the sticky ends of chromosomes from randomly clumping together"

PrepTutorEJDIC

1. (細いものの)『端』,先端《+『of』+『名』》 / (物語などの)『終り』,終結部《+『of』+『名』》 / (物事・期間の)『最後』《+『of』+『名』》;(…に)結末をつけるもの《+『to』+『名』》 / (…の)端の部分,末端部《『of』+『名』》 / 《しばしば複数形で》『目的』(purpose),目標(aim) / 《遠回しに》死,滅亡 / 《しばしば複数形で》切れ端,くず,残りもの / (事業などの)部門(part) / (フットボールで)エンド)前衛両端の選手または位置) / …‘を'『終わらせる』,終える / 〈物事が〉…‘の'終りとなる,‘を'締めくくる / 『終わる』,終了する(come to an end)
2. 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
3. 終り,終了;(物語・映画などの)結末 / (文の)語尾
4. 蛋白(たんばく)質

UpToDate Contents

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English Journal

• The Ku heterodimer: function in DNA repair and beyond.

• Fell VL1, Schild-Poulter C2.
• Mutation research. Reviews in mutation research.Mutat Res Rev Mutat Res.2015 Jan-Mar;763:15-29. doi: 10.1016/j.mrrev.2014.06.002. Epub 2014 Jul 4.
• Ku is an abundant, highly conserved DNA binding protein found in both prokaryotes and eukaryotes that plays essential roles in the maintenance of genome integrity. In eukaryotes, Ku is a heterodimer comprised of two subunits, Ku70 and Ku80, that is best characterized for its central role as the init
• PMID 25795113

• Multiple facets of TPP1 in telomere maintenance.

• Rajavel M1, Mullins MR1, Taylor DJ2.
• Biochimica et biophysica acta.Biochim Biophys Acta.2014 Sep;1844(9):1550-9. doi: 10.1016/j.bbapap.2014.04.014. Epub 2014 Apr 26.
• Telomeres are nucleoprotein complexes that cap the ends of all linear chromosomes and function to prevent aberrant repair and end-to-end chromosome fusions. In somatic cells, telomere shortening is a natural part of the aging process as it occurs with each round of cell division. In germ and stem ce
• PMID 24780581

• The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeres.

• Williams JM1, Ouenzar F2, Lemon LD3, Chartrand P2, Bertuch AA4.
• Genetics.Genetics.2014 Aug;197(4):1123-36. doi: 10.1534/genetics.114.164707. Epub 2014 May 30.
• Telomere length is tightly regulated in cells that express telomerase. The Saccharomyces cerevisiae Ku heterodimer, a DNA end-binding complex, positively regulates telomere length in a telomerase-dependent manner. Ku associates with the telomerase RNA subunit TLC1, and this association is required f
• PMID 24879463

Japanese Journal

• 1P038 テロメア1本鎖DNA結合蛋白質Pot1とテロメア1本鎖DNAとの相互作用の熱力学的特性(蛋白質 B) 構造・機能相関))

• 古川 亜矢子,鳥越 秀峰
• 生物物理 45(SUPPLEMENT_1), S41, 2005-10-19
• NAID 110004571019

• Pot1, the putative telomere end-binding protein in fission yeast and humans

• BAUMANN P.
• Science 292, 1171-1175, 2001
• NAID 80012598556

Related Links

• pot1 telomere end-binding protein Pot1 []

The high affinity conserved DNA-binding activity of Pot1 protein is conferred by a DNA-binding domain consisting of two subdomains. model in which conformational selection and induced fit play important roles in the recognition of ...

• Telomerase recruitment by the telomere end binding protein ...

Abstract The telomeric G-overhangs of the ciliate Stylonychia lemnae fold into a G-quadruplex DNA structure in vivo. Telomeric G-quadruplex formation requires the presence of two telomere end binding proteins, TEBP and TEBP, and ...

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★リンクテーブル★

リンク元	「telomere-binding protein」「テロメア末端結合タンパク質」
関連記事	「binding」「end」「binding protein」「ending」

「telomere-binding protein」

　　[★]

• テロメア結合タンパク質

関

TBP、telomere end-binding protein

「テロメア末端結合タンパク質」

　　[★]

英

telomere end-binding protein

関

テロメア結合タンパク質

「binding」

　　[★]

• n.

• 結合、バインディング

• adj.

• 結合性の

関

affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union

　 　 　 　 　

「end」

　　[★]

• n.

• 終わり、末端、端、目標

• v.

• 終了する、終わる

関

aim、brink、cease、complete、conclude、corner、distal、eventuate、extremity、goal、object、objective、side、terminal、terminally、terminate、termination

　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　

「binding protein」

　　[★]

• 結合タンパク質、結合タンパク、結合蛋白質、結合蛋白

関

BP、carrier protein、transport protein

「ending」

　　[★]

• n.

• 終末

関

terminal、terminally