- 関
- TBP、telomere end-binding protein
WordNet
- executed with proper legal authority; "a binding contract"
- the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
- strip sewn over or along an edge for reinforcement or decoration
- the capacity to attract and hold something
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- either (free) end of a eukaryotic chromosome; "telomeres act as caps to keep the sticky ends of chromosomes from randomly clumping together"
PrepTutorEJDIC
- 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
- 蛋白(たんばく)質
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/12/28 09:38:00」(JST)
[Wiki en表示]
Telomere-binding proteins are proteins that mediate telomere function by binding to them.[1][2] There are two types of telomere-binding proteins: single-strand DNA telomere binding proteins and double-strand DNA telomere binding proteins.[3]
References
- ^ Telomere-Binding Proteins at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Keiko Hiyama (2009). Telomeres and Telomerase in Cancer. シュプリンガー・ジャパン株式会社. pp. 100–. ISBN 978-1-60327-306-0. Retrieved 4 December 2010.
- ^ Nosek, Jozef (2008-06-02). Origin and Evolution of Telomeres. Landes Bioscience.
Cytogenetics: chromosomes
|
|
Basic
concepts |
- Karyotype
- Ploidy
- Genetic material/Genome
- Chromatin
- Euchromatin
- Heterochromatin
- Chromosome
- Chromatid
- Nucleosome
- Nuclear organization
|
|
Types |
- Autosome/Sex chromosome (or allosome or heterosome)
- Macrochromosome/Microchromosome
- Circular chromosome/Linear chromosome
- Extra chromosome (or accessory chromosome)
- Supernumerary chromosome
- A chromosome/B chromosome
- Lampbrush chromosome
- Polytene chromosome
- Dinoflagellate chromosomes
- Homologous chromosome
- Isochromosome
- Satellite chromosome
- Centromere position
- Metacentric
- Submetacentric
- Telocentric
- Acrocentric
- Holocentric
- Centromere number
- Acentric
- Monocentric
- Dicentric
- Polycentric
|
|
Processes
and evolution |
- Mitosis
- Meiosis
- Structural alterations
- Chromosomal inversion
- Chromosomal translocation
- Numerical alterations
- Aneuploidy
- Euploidy
- Polyploidy
- Paleopolyploidy
- Polyploidization
|
|
Structures |
- Telomere: Telomere-binding protein (TINF2)
- Protamine
Histone
|
|
|
Centromere
|
- A
- B
- C1
- C2
- E
- F
- H
- I
- J
- K
- M
- N
- O
- P
- Q
- T
|
|
|
See also |
- Extrachromosomal DNA
- List of organisms by chromosome count
- List of chromosome lengths for various organisms
- List of sequenced genomes
|
UpToDate Contents
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English Journal
- Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing.
- Lin J1, Countryman P2, Chen H3, Pan H2, Fan Y4, Jiang Y4, Kaur P2, Miao W5, Gurgel G6, You C7, Piehler J7, Kad NM8, Riehn R2, Opresko PL9, Smith S10, Tao YJ4, Wang H11.
- Nucleic acids research.Nucleic Acids Res.2016 Jun 13. pii: gkw518. [Epub ahead of print]
- Proper chromosome alignment and segregation during mitosis depend on cohesion between sister chromatids. Cohesion is thought to occur through the entrapment of DNA within the tripartite ring (Smc1, Smc3 and Rad21) with enforcement from a fourth subunit (SA1/SA2). Surprisingly, cohesin rings do not p
- PMID 27298259
- Telomere-binding protein regulates the chromosome ends through the interaction with histone deacetylases in Arabidopsis thaliana.
- Lee WK1, Cho MH2.
- Nucleic acids research.Nucleic Acids Res.2016 Jun 2;44(10):4610-24. doi: 10.1093/nar/gkw067. Epub 2016 Feb 8.
- Telomeres are nucleoprotein complexes at the end of eukaryotic chromosomes. Many telomere-binding proteins bind to telomeric repeat sequences and further generate T-loops in animals. However, it is not clear if they regulate telomere organization using epigenetic mechanisms and how the epigenetic mo
- PMID 26857545
- Application of Created Restriction Site PCR-RFLP to Identify POT1 Gene Polymorphism.
- Wang T1, Wang S, Duan X, Feng X, Wang P, Yao W, Wu Y, Feng F, Yu S, Wu Y, Wang W.
- Biochemistry. Biokhimii︠a︡.Biochemistry (Mosc).2016 Jun;81(6):624-7. doi: 10.1134/S0006297916060092.
- Protection of telomeres protein 1 (POT1) plays pivotal roles in protection of chromosome ends and regulation of telomere length with other telomere binding proteins; its genetic polymorphisms are associated with many diseases. In this study, we explored a novel PCR-RFLP method for typing the single
- PMID 27301291
Japanese Journal
- Fission Yeast Pot1 and RecQ Helicase Are Required for Efficient Chromosome Segregation
- Takahashi Katsunori,Imano Ryota,Kibe Tatsuya,Seimiya Hiroyuki,Muramatsu Yukiko,Kawabata Naoki,Tanaka Genki,Matsumoto Yoshitake,Hiromoto Taisuke,Koizumi Yuka,Nakazawa Norihiko,Yanagida Mitsuhiro,Yukawa Masashi,Tsuchiya Eiko,Ueno Masaru
- Molecular and Cellular Biology 31(3), 495-506, 2011-02
- … Pot1 is a single-stranded telomere-binding protein that is conserved from fission yeast to mammals. … Deletion of Schizosaccharomyces pombe pot1+ causes immediate telomere loss. …
- NAID 120004205356
- 1P-102 マウステロメアDNAの4本鎖DNA構造とマウステロメア結合蛋白質Pot1のテロメアDNA結合ドメインとの相互作用(核酸-相互作用・複合体,第47回日本生物物理学会年会)
- Kaneda Kaoru,Torigoe Hidetaka
- 生物物理 49(SUPPLEMENT_1), S79, 2009-09-20
- NAID 110008101402
- 1TP5-04 マウステロメアDNAの4本鎖DNA構造とマウステロメア結合蛋白質Pot1のテロメアDNA結合ドメインとの相互作用(核酸-相互作用・複合体,第47回日本生物物理学会年会)
- Kaneda Kaoru,Torigoe Hidetaka
- 生物物理 49(SUPPLEMENT_1), S37, 2009-09-20
- NAID 110008101156
Related Links
- 1. Genes Dev. 2000 Jul 15;14(14):1777-88. The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein. Qi H(1), Zakian VA. ...
- Rad24-2 truncation protein affects telomere structure or recombination in a manner distinct from rad24-delta. Cdk1-dependent phosphorylation of Cdc13 is essential for efficient recruitment of the yeast telomerase complex to ...
Related Pictures
★リンクテーブル★
[★]
- 英
- telomere-binding protein、TBP
- 関
- TATA結合タンパク質、テロメア末端結合タンパク質
[★]
- 関
- telomere-binding protein
[★]
- 関
- affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union
[★]
- 関
- BP、carrier protein、transport protein