WordNet

of critical importance and consequence; "an acute (or critical) lack of research funds"
having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
of an angle; less than 90 degrees
any of various controls or devices for regulating or controlling fluid flow, pressure, temperature, etc.
an official responsible for control and supervision of a particular activity or area of public interest

PrepTutorEJDIC

(先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
〈U〉〈C〉(…の)(量・額などの)不足,欠乏《+『of』(『in』)+『名』》 / 〈C〉不足分,不足量,不足額 / 〈C〉(精神・肉体などの)欠陥
取り締まり人;調整者 / 調整装置

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1. 急性リンパ芽球性白血病における細胞遺伝学および分子遺伝学 cytogenetics and molecular genetics in acute lymphoblastic leukemia
2. 非定型生殖器（性分化疾患）を有する乳児の評価 evaluation of the infant with atypical genitalia disorder of sex development
3. 副腎ステロイド生合成 adrenal steroid biosynthesis
4. 先天性リポイド副腎過形成症 congenital lipoid adrenal hyperplasia
5. 急性リン酸腎症 acute phosphate nephropathy

Elustondo P1, Martin LA1, Karten B2.
Biochimica et biophysica acta.Biochim Biophys Acta.2016 Aug 23. pii: S1388-1981(16)30232-3. doi: 10.1016/j.bbalip.2016.08.012. [Epub ahead of print]
All animal subcellular membranes require cholesterol, which influences membrane fluidity and permeability, fission and fusion processes, and membrane protein function. The distribution of cholesterol among subcellular membranes is highly heterogeneous and the cholesterol content of each membrane mus
PMID 27565112

SF-1 deficiency causes lipid accumulation in Leydig cells via suppression of STAR and CYP11A1.

Hatano M1,2,3, Migita T4,5, Ohishi T1,6,7, Shima Y8, Ogawa Y3, Morohashi KI8, Hasegawa Y2, Shibasaki F1.
Endocrine.Endocrine.2016 Jul 25. [Epub ahead of print]
Genetic mutations of steroidogenic factor 1 (also known as Ad4BP or Nr5a1) have increasingly been reported in patients with 46,XY disorders of sex development (46,XY disorders of sex development). However, because the phenotype of 46,XY disorders of sex development with a steroidogenic factor 1 muta
PMID 27455990

Augmented expression of gamma-glutamyl transferase 5 (GGT5) impairs testicular steroidogenesis by deregulating local oxidative stress.

Li W1, Wu ZQ2, Zhang S3, Cao R4, Zhao J1, Sun ZJ5, Zou W6.
Cell and tissue research.Cell Tissue Res.2016 Jul 11. [Epub ahead of print]
An increasingly pro-oxidant environment has been widely implicated in causing dysfunction of testicular steroidogenesis, but little progress has been made in understanding the underlying molecular mechanism. Here, we report that gamma-glutamyl transferase 5 (GGT5), a key metabolism component respons
PMID 27397680

Ovarian Histological Findings in an Adult Patient with the Steroidogenic Acute Regulatory Protein (StAR) Deficiency Reveal the Impairment of Steroidogenesis by Lipoid Deposition

Ovarian Histological Findings in an Adult Patient with the Steroidogenic Acute Regulatory Protein (StAR) Deficiency Reveal the Impairment of Steroidogenesis by Lipoid Deposition