WordNet

of critical importance and consequence; "an acute (or critical) lack of research funds"
having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
of an angle; less than 90 degrees
a lack of competence; "pointed out the insufficiencies in my report"; "juvenile offenses often reflect an inadequacy in the parents" (同)inadequacy
(pathology) inability of a bodily part or organ to function normally
lack of an adequate quantity or number; "the inadequacy of unemployment benefits" (同)inadequacy, deficiency
of or derived from the cortex of the adrenal glands

PrepTutorEJDIC

(先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
不十分な[点],不足;不適当,不向き

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Livingstone DE1, Di Rollo EM2, Yang C2, Codrington LE2, Mathews JA2, Kara M2, Hughes KA2, Kenyon CJ2, Walker BR2, Andrew R2.
The Journal of endocrinology.J Endocrinol.2014 Aug;222(2):257-66. doi: 10.1530/JOE-13-0563. Epub 2014 May 28.
Patients with critical illness or hepatic failure exhibit impaired cortisol responses to ACTH, a phenomenon known as 'relative adrenal insufficiency'. A putative mechanism is that elevated bile acids inhibit inactivation of cortisol in liver by 5α-reductases type 1 and type 2 and 5β-reductase, res
PMID 24872577

Palmiere C1, de Froidmont S, Mangin P, Werner D, Lobrinus JA.
Journal of forensic sciences.J Forensic Sci.2014 Jul;59(4):1146-52. doi: 10.1111/1556-4029.12446. Epub 2014 Feb 19.
We herein report an autopsy case involving a 27-year-old Caucasian woman suffering from chronic adrenocortical insufficiency with a background of a polyendocrine disorder. Postmortem biochemistry revealed pathologically decreased aldosterone, cortisol, and dehydroepiandrosterone levels in postmortem
PMID 24673726

Policola C1, Stokes V2, Karavitaki N2, Grossman A2.
Endocrinology, diabetes & metabolism case reports.Endocrinol Diabetes Metab Case Rep.2014;2014:130071. doi: 10.1530/EDM-13-0071. Epub 2014 Jan 1.
Opiate drugs such as morphine are in extensive use for pain relief and palliation. It is well established that these drugs can cause changes in endocrine function, but such effects are not always sufficiently appreciated in clinical practice, especially in relation to the hypothalamic-pituitary-adre
PMID 24683482

Acute Adrenal Insufficiency after Unilateral Adrenalectomy in Cushing's Syndrome: Precipitation by Lithium-Induced Thyrotoxicosis during Cortisol Replacement.:Precipitation by Lithium-Induced Thyrotoxicosis during Cortisol Replacement

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Endocrine Journal 41(2), 177-182, 1994
… We present a patient with Cushing's syndrome due to adrenocortical adenoma who developed acute adrenal insufficiency one month after unilateral adrenalectomy. … Caution should therefore be exercised in administering lithium carbonate, especially when the patient's adrenal reserve is low, since even a mild degree of thyrotoxicosis can precipitate an acute adrenal crisis. …
NAID 130003549406

小西池穣一
医療 38(4), 377-382, 1984
compromised hostすなわち抵抗力の減弱した個体からの肺結核の発病の要因, 頻度と実態について検討を加えた. 過去6年間に退院した患者3782例のうち, 合併症を有する1110例(29.3%)を抽出したが, このうちcompromised hostから肺結核が発病したと考えられたのは28例(2.5%)であつた. 内訳は男15, 女13, 平均年令56才で, 基礎疾患は悪性腫瘍(術後), …
NAID 130004313387