マクログロブリン血症
WordNet
- the 23rd letter of the Roman alphabet (同)w, double-u
PrepTutorEJDIC
- Watt / West; Western
- wolfram(=tungsten)の原子記号
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/06/30 15:39:39」(JST)
[Wiki ja表示]
WM
- Windows Mail
- Windows Media
- Windows Me
- Windows Mobile
- ウィキメディア財団 (WikiMedia Foundation)
- ウィンドウマネージャ (Window Manager)
- ウォークマン (Walkman)
- WMフォーメーション - サッカーのフォーメーションの一つ
- WebMoney - WM Transfer Ltd社が運営するオンライン支払いサービス。
- 同じ英称のプリペイド電子決済サービスとその運営会社、ウェブマネーとは別
- 包装明細書 (Weight Memo) - 貿易に使われる書類の一つ
- 週刊少年マガジン の英称 (Weekly-Shonen Magazine?)
- レッスルマニア (WrestleMania) 米プロレス団体WWEの興行
- ウォーターマーク (WaterMark) FF14FCの一つ
|
このページは曖昧さ回避のためのページです。一つの語句が複数の意味・職能を有する場合の水先案内のために、異なる用法を一覧にしてあります。お探しの用語に一番近い記事を選んで下さい。このページへリンクしているページを見つけたら、リンクを適切な項目に張り替えて下さい。 |
[Wiki en表示]
WM Wm, wm, or variants may refer to:
Contents
- 1 Companies
- 2 Science and medicine
- 3 Technology and computing
- 4 Sport
- 5 Military
- 6 Transport
- 7 Other
Companies
- Wal-Mart, an American retailing chain
- WM, former New York stock exchange ticker symbol for Washington Mutual, a former American savings bank
- WM, New York stock exchange ticker symbol for Waste Management, Inc, a North American garbage company
Science and medicine
- Waldenström's macroglobulinemia, a rare form of blood cancer
- Working memory, a part of the short-term memory
- White matter, a type of brain tissue
Technology and computing
- Window Maker, a window manager for the X Window System
- X window manager, a part in the X Window System
- Windows Media, a multimedia framework for media creation and distribution for Microsoft Windows
- Windows Messenger, a part included in the Microsoft Windows XP operating system
- Windows Mobile, an operating system for Pocket PCs
Sport
- WM formation, a formation in association football, so called because it spells out the letters when viewed from above
- WrestleMania, a professional wrestling pay-per-view event
Military
- The licence plate code used by the Germany Navy (Kriegsmarine) in World War II, standing for "Wehrmacht Marine"
- Waterloo Medal, a medal awarded to British soldiers who fought in the Waterloo campaign in 1815
- Woman Marine, a female member of the United States Marine Corps
Transport
- Western Maryland Railway, a former railway in the United States
- Windward Islands Airways or Winair IATA airline code
Other
- Wm. (also Wm), an abbreviation of the name William
- The College of William & Mary, a public research university in Virginia
- Worshipful Master, the head of a lodge in freemasonry
- Wm. (also WM), weight (or) measurement in respect of shipping ocean freight Ref.
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Why is working memory related to intelligence? Different contributions from storage and processing.
- Dang CP1, Braeken J, Colom R, Ferrer E, Liu C.Author information 1a Department of Psychology , Guangzhou Medical University , China.AbstractDomain-specific contributions of working memory (WM), short-term memory (STM), and executive functioning (EF) to individual differences in intelligence were analysed using a latent variable approach. A sample of 345 participants completed a battery of 24 tests tapping the constructs of interests as comprehensively as possible. Visuospatial and verbal STM and WM tasks were administered along with three subcomponents of EF, namely inhibition, planning, and shifting. Intelligence was assessed by non-verbal/abstract/fluid intelligence (Gf) and verbal/crystallised intelligence (Gc) standardised tests. Structural equation modelling results show that EF is the main predictor of Gf, whereas verbal STM is the main predictor of Gc. Storage and processing providing different contributions to the prediction of Gf and Gc supports the view that both short-term storage and executive functioning account for the relationship between WM and intelligence. This main conclusion stresses the importance of acknowledging core cognitive constructs as being hierarchical systems with general and domain-specific mechanisms.
- Memory (Hove, England).Memory.2014 Jun;22(4):426-41. doi: 10.1080/09658211.2013.797471. Epub 2013 Jun 7.
- Domain-specific contributions of working memory (WM), short-term memory (STM), and executive functioning (EF) to individual differences in intelligence were analysed using a latent variable approach. A sample of 345 participants completed a battery of 24 tests tapping the constructs of interests as
- PMID 23745736
- Effects of impoverished environmental conditions on working memory performance.
- Engel de Abreu PM1, Puglisi ML, Cruz-Santos A, Befi-Lopes DM, Martin R.Author information 1a EMACS Research Unit , University of Luxembourg , Luxembourg.AbstractThis cross-cultural study investigates the impact of background experience on four verbal and visuo-spatial working memory (WM) tasks. A total of 84 children from low-income families were recruited from the following groups: (1) Portuguese immigrant children from Luxembourg impoverished in terms of language experience; (2) Brazilian children deprived in terms of scholastic background; (3) Portuguese children from Portugal with no disadvantage in either scholastic or language background. Children were matched on age, gender, fluid intelligence, and socioeconomic status and completed four simple and complex span tasks of WM and a vocabulary measure. Results indicate that, despite large differences in their backgrounds and language abilities, the groups exhibited comparable performance on the visuo-spatial tasks dot matrix and odd-one-out and on the verbal simple span task digit recall. Group differences emerged on the verbal complex span task counting recall with children from Luxembourg and Portugal outperforming children from disadvantaged schools in Brazil. The study suggests that whereas contributions of prior knowledge to digit span, dot matrix, and odd-one-out are likely to be minimal, background experience can affect performance on counting recall. Implications for testing WM capacity in children growing up in poverty are discussed.
- Memory (Hove, England).Memory.2014 Jun;22(4):323-31. doi: 10.1080/09658211.2013.781186. Epub 2013 Mar 26.
- This cross-cultural study investigates the impact of background experience on four verbal and visuo-spatial working memory (WM) tasks. A total of 84 children from low-income families were recruited from the following groups: (1) Portuguese immigrant children from Luxembourg impoverished in terms of
- PMID 23531204
- Failure to benefit from target novelty during encoding contributes to working memory deficits in schizophrenia.
- Mayer JS1, Kim J, Park S.Author information 1a Department of Psychology , Vanderbilt University , 111 21st Ave South, Nashville , TN 37240 , USA.AbstractIntroduction Although working memory (WM) impairments are well documented in schizophrenic patients (PSZ), the underlying mechanisms are poorly understood. The aim of this study was to investigate the role of target salience during encoding to determine whether impaired visual attention in PSZ leads to poor WM. Methods Thirty-one PSZ and 28 demographically matched healthy controls (HC) performed a spatial delayed-response task. Attentional demands were manipulated during WM encoding by presenting high salient (novel) or low salient (familiar) targets. Participants also rated their level of response confidence at the end of each trial, allowing us to analyse different response types. Results WM was impaired in PSZ. Increasing target salience by increasing novelty improved WM performance in HC but not in PSZ. Poor WM performance in PSZ was largely due to an increase in the proportion of incorrect but high confident responses most likely reflecting a failure to encode the correct target. Conclusions Our findings suggest that dysfunctions of non-mnemonic attentional processes during encoding contribute to WM impairments in schizophrenia and may represent an important target for cognitive remediation strategies.
- Cognitive neuropsychiatry.Cogn Neuropsychiatry.2014 May;19(3):268-79. doi: 10.1080/13546805.2013.854199. Epub 2013 Nov 11.
- Introduction Although working memory (WM) impairments are well documented in schizophrenic patients (PSZ), the underlying mechanisms are poorly understood. The aim of this study was to investigate the role of target salience during encoding to determine whether impaired visual attention in PSZ leads
- PMID 24215367
Japanese Journal
- Determinant Processing Factors of Recall Performance in Reading Span Tests : An Empirical Study of Japanese EFL Learners
- 中西 弘,横川 博一
- 大学英語教育学会紀要 (53), 93-108, 2011-10-27
- … These results suggest that syntactic processing places a heavy cognitive load on working memory (WM) resources, thereby leaving few resources for storage functions while Japanese EFL learners are performing the RSTs. …
- NAID 110008897627
- NIRSを用いた Working Memory 課題時の前頭-後頭血流動態解析
- 小川 雄太郎,飛佐 洋平,小谷 潔,神保 泰彦
- 電気学会研究会資料. MBE, 医用・生体工学研究会 2011(112), 49-54, 2011-09-20
- NAID 10029663023
Related Links
- 電子マネーWebMoney(ウェブマネー)は、オンラインゲームや音楽ダウンロードなどインターネット決済で最も標準的なプリペイド電子マネー。 コンビニで誰でも購入OK&個人情報不要でセキュリティ面でも安心です。
- The official site of WM PRODUCTION TEAM. WM official site, official shop Wellington, WM international.
Related Pictures
![Thank You to our Generous Conference](https://1mg.info/0/e/u/0229.jpg)
![WM Logo: Self branding | PDF 3](https://1mg.info/0/e/u/0230.jpg)
![WM Disputes (@WMDisputes) | Twitter](https://1mg.info/0/e/u/0231.jpg)
![Klub-WM - Streitfall: Freistoß-Spray ein](https://1mg.info/0/e/u/0232.jpg)
![Dribbble - WM monogram ambigram by Henric](https://1mg.info/0/e/u/0233.jpg)
![WM 2014 Spielplan als PDF zum](https://1mg.info/0/e/u/0234.jpg)
![Recycle Often. Recycle Right. | Home](https://1mg.info/0/e/u/0235.jpg)
★リンクテーブル★
[★]
- 英
- macroglobulinemia
- 同
- ワルデンシュトレーム・マクログロブリン血症 Waldenström macroglobulinemia Waldenstrom macroglobulinemia WM、原発性マクログロブリン血症 primary macroglobulinemia、マクログロブリネミア
- 関
- 単クローン性免疫グロブリン血症。高γグロブリン血症
- first aid step1 2006 p.304
WCH.2669
pathologic feature
|
MCL
|
B-cell CLL
|
FL
|
MZL
|
WM
|
MM
|
paraprotein
|
None
|
Small IgG or IgM
|
Usually none
|
Small IgM
|
IgM (large)
|
IgA, IgG
|
morphology
|
Centrocyte-like; small-to-medium-sized lymphocytes
|
Small lymphocyte with clumped chromatin
|
Follicle center cells (follicular pattern)
|
Monocytoid B cells, heterogeneous
|
Plasmacytoid lymphocytes and plasma cells
|
Plasma cells
|
surface Ig
|
+
|
+
|
+
|
+
|
+
|
+
|
cytoplasmic Ig
|
-
|
-
|
-
|
-
|
++
|
+++
|
CD19
|
+
|
+
|
+
|
+
|
+
|
+
|
CD20
|
++
|
+
|
++
|
+
|
+
|
15% CD20+
|
CD23
|
-
|
+
|
±
|
-
|
-
|
-
|
CD22
|
+
|
-
|
-
|
+
|
+
|
-
|
CD38
|
-
|
±
|
-
|
-
|
+
|
++
|
CD138
|
-
|
-
|
-
|
-
|
+
|
++
|
CD5
|
+
|
+
|
-
|
-
|
Usually CD5-
|
-
|
CDlO
|
±
|
-
|
+
|
-
|
-
|
-
|
cytogenetic aberrations
|
t(11;14)(q13;q32), cyclin Dl+
|
13q-, 6q-, +12, 11q23-
|
t(14;18)(q32; q21), bcl-2+
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t(11;18)(q21; q21), +3
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6q-
|
t(4;14)(p16.3;q32),t(11;14)(q13;q32),t(14;16)(q32;q23), other +14q32,13q-, aneuploidy
|
somatic hypermutation
|
?
|
+, 50%; -, 50%
|
++
|
++
|
+++
|
+++
|
bone marrow involvement (%)
|
25
|
~100
|
85
|
50
|
>90
|
100
|
bone lytic lesions
|
No
|
No
|
No
|
No
|
5%
|
70%
|
概念
病因
疫学
症状
- also see WCH.2671
- 血管粘稠度上昇 + 病的蛋白質による血管内皮損傷:[眼症状] ソーセージ様の網膜血管のうっ滞・拡張、網膜出血、綿花様白斑、網膜静脈閉塞症、滲出性網膜剥離
- リンパ球の浸潤による症状:weakness, 体重減少、骨痛、肝脾腫、リンパ節腫
診断
鑑別診断
- 慢性リンパ性白血球、骨髄腫(IgM myeloma: bone lesion, CD138+ plamac cell infiltration)、kymphocytic lymphoma
myelomaとの共通点と異差
HIM.706
- 鼻出血、視力障害(visual disturbance)、神経症状(めまい、頭痛、一時的な麻痺)
QB.G-269 WCH.2671
|
多発性骨髄腫
|
マクログロブリン血症
|
|
ワルデンシュトレーム・マクログロブリン血症
|
|
MM
|
WM
|
|
病変のfocus
|
主に骨髄
|
主にリンパ組織
|
集積することで出現する症状が異なる
|
腫瘍細胞
|
形質細胞
|
やや幼弱なB細胞
|
|
赤血球連戦形成
|
+
|
+++
|
IgMのせい
|
出血傾向
|
少
|
多
|
IgMのせい
|
肝脾腫、リンパ節腫脹
|
|
骨破壊
|
70%
|
5%
|
|
過粘稠度症候群
|
少
|
多
|
IgMのせい
|
M蛋白
|
IgG,IgA,IgD,IgE,BJP
|
IgM
|
|
腎障害
|
多
|
少
|
IgMは糸球体濾過されにくい
|
眼底変化
|
少
|
多
|
IgMのせい
|
年齢
|
40-60歳代
|
40-70歳代
|
|
検査
血算
- 赤沈:高度促進
- 貧血
- 白血球:増多(リンパ球様細胞の増多)
- 血小板:減少 ← MMより頻度は低い、はず。一般的でなく、病気の末期まで出現しない(WCH.2671)。患者のほとんどが正常範囲内で、10万/ul以下であるのはほんの9%の患者であり、本疾患における血小板減少症の有病率は22%と報告されている(WCH.2671)。
血液生化学
尿検査
治療
予後
USMLE
[★]
- 同
- wall motion abnormality, 壁運動異常
壁運動異常 wall motion abnomality
[★]
ポークウィードマイトジェン, pokeweed mitogen
[★]
- 同
- regional wall motion, 局所壁運動
[★]
- 関
- ポークウィードマイトジェン
[★]