- 関
- TRAF-3、TRAF3
WordNet
- having partial rights and privileges or subordinate status; "an associate member"; "an associate professor"
- a person who joins with others in some activity or endeavor; "he had to consult his associate before continuing"
- a person with subordinate membership in a society, institution, or commercial enterprise; "associates in the law firm bill at a lower rate than do partners"
- any event that usually accompanies or is closely connected with another; "first was the lightning and then its thunderous associate"
- make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all" (同)tie_in, relate, link, colligate, link up, connect
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
- the 20th letter of the Roman alphabet (同)t
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
PrepTutorEJDIC
- 〈人〉'を'(…の)『仲間に加える』,(…に)連合させる《+『名』〈人〉+『with』+『名』》 / (…と)…'を'結びつけて考える(起こす)《+『名』+『with』+『名』》 / (…と)『仲間になる』,交際する《+『with』+『名』》 / (…と)合体する,提携する《+『with』+『名』》 / 『仲間』,『同僚』;組合員 / 準会員 / 付属物;連想されるもの / 連合した;仲間の,同僚の / 補助の,準…
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
- tritiumの化学記号
- =sense organ / 受信装置
UpToDate Contents
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- 1. 腫瘍壊死因子受容体-1関連周期性発熱症候群（TRAPS） tumor necrosis factor receptor 1 associated periodic syndrome traps
- 2. 周期性発熱症候群およびその他の自己炎症性疾患：概要 periodic fever syndromes and other autoinflammatory diseases an overview
- 3. 複合免疫不全 combined immunodeficiencies
- 4. 全身性自己免疫疾患における心膜病変 pericardial involvement in systemic autoimmune diseases
- 5. 腫瘍壊死因子α阻害剤および抗酸菌感染 tumor necrosis factor alpha inhibitors and mycobacterial infections
English Journal
- TRAF3 negatively regulates calcineurin-NFAT pathway by targeting calcineurin B subunit for degradation.
- Wang X, Huang Y, Li L, Wei Q.SourceDepartment of Biochemistry and Molecular Biology, College of Life Sciences, Beijing Normal University, Beijing Key Laboratory, Beijing, People's Republic of China; College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, People's Republic of China.
- IUBMB life.IUBMB Life.2012 Sep;64(9):748-56. doi: 10.1002/iub.1060. Epub 2012 Jun 20.
- Calcineurin (CN) is the only serine/threonine specific protein phosphatase regulated by Ca(2+) /calmodulin (CaM), which is composed of catalytic A subunit (CNA) and regulatory B subunit (CNB). Tumor necrosis factor (TNF) receptor associated factor 3 (TRAF3) is an essential component in the Toll like
- PMID 22715070
- Activation of the noncanonical NF-κB pathway by HIV controls a dendritic cell immunoregulatory phenotype.
- Manches O, Fernandez MV, Plumas J, Chaperot L, Bhardwaj N.SourceCancer Institute, N ew York University Langone Medical Center, New York, NY 10016.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2012 Aug 28;109(35):14122-7. Epub 2012 Aug 9.
- HIV modulates plasmacytoid dendritic cell (pDC) activation via Toll-like receptor 7, inducing type I IFN and inflammatory cytokines. Simultaneously, pDCs up-regulate the expression of indoleamine 2,3 dioxygenase (IDO), which is essential for the induction of regulatory T cells (Tregs), which functio
- PMID 22879398
Japanese Journal
- 原発性マクログロブリン血症の診断と治療 (造血器腫瘍学 : 基礎と臨床の最新研究動向) -- (リンパ系腫瘍の臨床)
- 三輪 哲義
- 日本臨床 70(1018 増刊2), 642-662, 2012-04
- NAID 40019283025
- 自己抗体産生RP105陰性B細胞上に発現する B-cell maturation antigen は, 全身性エリテマトーデスの治療標的となりうるか
- 小荒田 秀一,田代 知子,末松 梨絵,井上 久子,大田 明英,多田 芳史
- 日本臨床免疫学会会誌 = Japanese journal of clinical immunology 35(1), 38-45, 2012-02-28
- … RP105（CD180）はTLR（toll-like receptor）関連分子であるが，SLEにおいてRP105を欠損するB細胞（RP105（−）B細胞）が出現し，自己抗体を産生する．したがって，同細胞は，SLE治療の有力な標的となりうると考えられる．そのために，同細胞に特異的に発現する抗原の網羅的検索をDNAマイクロアレイ法とフローサイトメトリーで行った．マイクロアレイの結果，BCMA（B-cell maturation antigen）の発現が特異的に高いことが示唆され …
- NAID 10030465586
- W9-5 TRAF6は制御性T細胞のTh2型炎症の抑制に関与する
- 武藤 剛,新倉 芹菜,森田 林平,小林 隆志,吉村 昭彦
- 日本臨床免疫学会会誌 35(4), 320b-320b, 2012
- … アダプター分子TRAF6（TNF receptor-associated factor 6）はNF-kBの活性化に関与し，自然免疫反応の制御において重要な役割を果たすが，近年T細胞における機能が注目されている．今回我々は，制御性T細胞特異的にTRAF6を欠損させたマウスは，著明な全身リンパ節腫脹・皮膚炎・関節炎を自然発症することを発見した．このマウスでは末梢リンパ組織におけるTreg数の …
- NAID 130003364032
Related Links
- Upon exposure to bacterial lipopolysaccharide (LPS), recruited to a transient complex containing TLR4, TRAF3, TRAF6, IKBKG, MAP3K7, MYD88, TICAM1, BIRC2, BIRC3 and UBE2N By similarity . Interacts with Epstein-Barr virus protein ...
- TRAF3 (TNF Receptor Associated Factor 3), Authors: Valérie Kedinger. Published in: Atlas Genet Cytogenet Oncol Haematol.
Related Pictures
★リンクテーブル★
| リンク元 | 「TRAF3」「TNF受容体関連因子3」 |
| 関連記事 | 「associate」「fact」「TNF receptor」「factor」「T」 |
「TRAF3」
- 関
- TNF receptor-associated factor 3、TRAF-3
「TNF受容体関連因子3」
「associate」
- vt.
- 結合する、連合させる。連想によって結びつける。(人を)仲間/友達などとしての関係に置く。(化)会合させる
- vi.
- 仲間/友人などとして交際する(with)。一つにまとめる、連合する
- n.
- 仕事仲間、提携者、同僚。友人、朋友。準会員。従業員、社員
- 密接な蒸す偽付きのある物、付随する物、つきもの。準国家
- 連想によって心に浮かぶ言葉/思い、連想物
- adj.
- 仲間の、同僚の。製紙機械員に次ぐ資格の
- 付随する、連想される
- 関
- accompany、association、associative、attach、bearing、bind、binding、bond、bonding、coassemble、colleague、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、correlate、correlation、couple、dock、engage、engagement、federation、implication、join、joint、ligate、link、linkage、peer、pertinent、reference、relate、relation、relationship、relative、relevance、relevant、symphysial、union
「fact」
- n.
「TNF receptor」
「factor」
- n.
「T」