CD45欠損症
PrepTutorEJDIC
- 〈U〉〈C〉(…の)(量・額などの)不足,欠乏《+『of』(『in』)+『名』》 / 〈C〉不足分,不足量,不足額 / 〈C〉(精神・肉体などの)欠陥
- certificate of deposit / (また『C.D.』)Civil Defense民間防衛
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English Journal
- Peripheral blood hematopoietic stem and progenitor cell frequency is unchanged in patients with alpha-1-antitrypsin deficiency.
- de Kruijf EJ1, Alkemade GM, van Os R, Fibbe WE, van Pel M.
- International journal of hematology.Int J Hematol.2014 Apr 22. [Epub ahead of print]
- Granulocyte-colony-stimulating factor (G-CSF)-induced hematopoietic stem and progenitor cell (HSPC) mobilization is associated with the release of neutrophil-derived proteases. Previously, we have shown that alpha-1-antitrypsin (AAT) inhibits these proteases in mice, resulting in inhibition of HSPC
- PMID 24752699
- Complex regulation of acute and chronic neuroinflammatory responses in mouse models deficient for nuclear factor kappa B p50 subunit.
- Rolova T1, Puli L1, Magga J2, Dhungana H1, Kanninen K1, Wojciehowski S1, Salminen A3, Tanila H1, Koistinaho J4, Malm T1.
- Neurobiology of disease.Neurobiol Dis.2014 Apr;64:16-29. doi: 10.1016/j.nbd.2013.12.003. Epub 2013 Dec 15.
- Inflammation is a major mechanism of acute brain injury and chronic neurodegeneration. This neuroinflammation is known to be substantially regulated by the transcription factor NF-κB, which is predominantly found in the form of heterodimer of p65 (RelA) and p50 subunit, with p50/p50 homodimers bein
- PMID 24345324
- Anti-mouse CD52 monoclonal antibody ameliorates iron-deficient anaemia in IL-10 knockout mice.
- Wang H, Dong J, Zuo L, Liu J, Zhu W, Li Y, Gu L, Zhao J, Zhang L, Gong J, Zhang W, Li N, Li J.
- The British journal of nutrition.Br J Nutr.2014 Mar 28;111(6):987-95. doi: 10.1017/S0007114513003413. Epub 2013 Oct 28.
- Approximately 50 % of patients with inflammatory bowel disease (IBD) suffer from anaemia, with Fe deficiency being the most common cause. CD52 monoclonal antibody (mAb) targets the cell surface CD52 and is effective in depleting lymphocytes through cytolytic effects in vivo. The aim of the present
- PMID 24160470
Japanese Journal
- The Differences in the Expression of CD45 Isoforms on Peripheral Blood Lymphocytes Derived from Patients with Seasonal or Perennial Atopic Allergy.
- Pawlik Izabella,Mackiewicz Urszula,Lacki Jan K.,Wiktorowicz Krzysztof,Konys Jan
- The Tohoku Journal of Experimental Medicine 182(1), 1-8, 1997
- … Flow cytometry was employed to detect the expression of CD3, CD4, CD4CD45RA, CD4CD45RO, CD8, CD16, and CD19 molecules on peripheral blood lymphocytes. … Allergic patients showed a decreased proportion of memory (CD4+CD45RO+) T cells compared with healthy subject (p<0.05). … The proportion of naive (CD4+CD45RA+) helper T cells did not differ between allergic patients and controls. …
- NAID 130004458856
- Deficiency of suppressor-inducer (CD4+CD45RA+) T cells in autism
Related Links
- Converging lines of evidence indicate dysregulation of the key immunoregulatory molecule CD45 (also known as leukocyte common antigen) in Alzheimer's disease (AD). We report that transgenic mice overproducing amyloid-β peptide (A ...
- MalaCards: Cd45 Deficiency is related to complement deficiency and t cell deficiency. An important gene associated with Cd45 Deficiency is PTPRC (protein tyrosine phosphatase, receptor type, C), and among its related and . ...
Related Pictures
★リンクテーブル★
[★]
- 英
- CD45 deficiency
- 関
- CD45
[★]
- 不足、欠乏、欠失、欠如、欠損、不十分。栄養不足、栄養素欠乏、欠乏症。(遺伝子)(染色体内の)遺伝子欠失
- 欠けているもの、不足している物。不足分。不完全なもの、欠点のあるもの
- 関
- absence, agenesis, dearth, defect, defective, deficient, deficit, delete, deletion, deletional, depletion, deprivation, deprive, lack, miss, missing, morphological defect, paucity, scarce, scarcity, starve
[★]
- 同
- leukocyte common antigen LCA, T200, B220
- 関
- CD45RO, CD45RA, CD45RB
- 表面抗原分類
発現細胞
分子量
機能
- tyrosine phosphatase, augments sinnaling through antigen receptor of B and T cells, multiple isoforms result from alternative splicing
ファミリー
疾患との関連
[★]
[★]
- 同
- T4, Leucine-SA, Leucine-3B
- 関
- 表面抗原分類