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- 1. 移植片対宿主病の病因 pathogenesis of graft versus host disease
English Journal
- Suppression of Th1 cytokine production by a peptide derived from C4b.
- Takeda Y, Kaneda K, Jimma F, Shiobara N, Saniabadi AR, Wakabayashi I.SourceDepartment of Environmental and Preventive Medicine, Hyogo College of Medicine, Mukogawa-cho 1-1, Nishinomiya, Hyogo, 663-8501, Japan.
- Inflammation research : official journal of the European Histamine Research Society ... [et al.].Inflamm Res.2013 Nov;62(11):951-9. doi: 10.1007/s00011-013-0650-z. Epub 2013 Aug 25.
- OBJECTIVES: The complement system has been proposed to play a significant role in the regulation of T-cell responses. However, the precise mechanism underlying C4-induced immune tolerance remains to be clarified. We recently reported that monomeric C4b inhibits CXCL10 production from blood cells. Th
- PMID 23979690
- Immunophenotypic profile of nucleated erythroid progenitors during maturation in regenerating bone marrow.
- Fajtova M, Kovarikova A, Svec P, Kankuri E, Sedlak J.SourceCancer Research Institute.
- Leukemia & lymphoma.Leuk Lymphoma.2013 Nov;54(11):2523-30. doi: 10.3109/10428194.2013.781167. Epub 2013 Apr 23.
- Abstract This study introduces an in-depth flow cytometric method for the analysis of nucleated erythroid progenitors during bone marrow regeneration. Initial immunophenotypic analysis with the conventional erythroid-associated markers CD36, CD71 and CD235a was supplemented with the analysis of addi
- PMID 23452116
- Mesenchymal stem cells promote leukaemic cells aberrant phenotype from B-cell acute lymphoblastic leukaemia.
- Rodríguez-Pardo VM, Aristizabal JA, Jaimes D, Quijano SM, Reyes ID, Herrera MV, Solano J, Vernot JP.SourceGrupo de Inmunobiología y Biología Celular, Facultad de Ciencias, Pontificia Universidad Javeriana, Cra 7(a), No. 40-62, Bogotá D.C., Colombia.
- Hematology/oncology and stem cell therapy.Hematol Oncol Stem Cell Ther.2013 Oct 23. pii: S1658-3876(13)00074-5. doi: 10.1016/j.hemonc.2013.09.002. [Epub ahead of print]
- BACKGROUND AND OBJECTIVES: The role of bone marrow-mesenchymal stem cells (BM-MSC) in leukaemic cell control is controversial. The purpose of this work was to evaluate BM-MSC role regarding the viability, proliferation and immunophenotype of normal B-cell precursors from control (Ct) patients and le
- PMID 24161606
Japanese Journal
- Usefulness of CD4^+CD45RB^<high> CD25^- Cell-Transferred SCID Mice for Preclinical Evaluation of Drugs for Inflammatory Bowel Disease
- Hirano Daisuke,Kudo Shihoko
- Journal of pharmacological sciences 110(2), 169-181, 2009-06-20
- NAID 10025737097
- Targeting CD45RB alters T cell migration and delays viral clearance
- LIM Bock,SUTHERLAND Robyn M.,ZHAN Yifan,DELIYANNIS Georgia,BROWN Lorena E.,LEW Andrew M.
- International immunology 18(2), 291-300, 2006-02-01
- NAID 10020621360
Related Pictures
★リンクテーブル★
| リンク元 | 「CD45RO」「CD45RA」 |
| 関連記事 | 「CD45」「CD45R」 |
「CD45RO」
発現細胞
分子量
- 180
機能
- isoform of CD45 containing the A, B, and C exons
ファミリー
- fibronectin type II
発現の強度
- 記憶T細胞では強く発現するので、マーカーとして使われる。
| naive T cell | effector T cell | memory T cell | |
| CD45RO | ＋ | ＋＋＋ | ＋＋＋ |
| CD45RA | ＋ | ＋＋＋ | ＋＋＋ |
「CD45RA」
発現細胞
- B細胞、T細胞サブセット(naive T cells), 単球
分子量
- 205-220
機能
- isoform of CD45 containing the A exon
ファミリー
- fibronectin type II
「CD45」
発現細胞
- 全ての造血細胞
分子量
- 180-240 kDa
機能
- tyrosine phosphatase, augments sinnaling through antigen receptor of B and T cells, multiple isoforms result from alternative splicing
ファミリー
- fibronectin type III
疾患との関連
- ホジキンリンパ腫：CD45は発現していない。