WordNet
- place signs, as along a road; "sign an intersection"; "This road has been signed"
- (medicine) any objective evidence of the presence of a disorder or disease; "there were no signs of asphyxiation"
- a perceptible indication of something not immediately apparent (as a visible clue that something has happened); "he showed signs of strain"; "they welcomed the signs of spring" (同)mark
- a character indicating a relation between quantities; "dont forget the minus sign"
- a fundamental linguistic unit linking a signifier to that which is signified; "The bond between the signifier and the signified is arbitrary"--de Saussure
- a gesture that is part of a sign language
- a public display of a message; "he posted signs in all the shop windows"
- engage by written agreement; "They signed two new pitchers for the next season" (同)contract, sign on, sign_up
- approve and express assent, responsibility, or obligation; "All parties ratified the peace treaty"; "Have you signed your contract yet?" (同)ratify
- communicate silently and non-verbally by signals or signs; "He signed his disapproval with a dismissive hand gesture"; "The diner signaled the waiters to bring the menu" (同)signal, signalize, signalise
- mark with ones signature; write ones name (on); "She signed the letter and sent it off"; "Please sign here" (同)subscribe
- be engaged by a written agreement; "He signed to play the casino on Dec. 18"; "The soprano signed to sing the new opera"
- communicate in sign language; "I dont know how to sign, so I could not communicate with my deaf cousin"
- determine the order of constituents in; "They sequenced the human genome"
- a following of one thing after another in time; "the doctor saw a sequence of patients" (同)chronological sequence, succession, successiveness, chronological succession
- film consisting of a succession of related shots that develop a given subject in a movie (同)episode
- serial arrangement in which things follow in logical order or a recurrent pattern; "the sequence of names was alphabetical"; "he invented a technique to determine the sequence of base pairs in DNA"
- several repetitions of a melodic phrase in different keys
- arrange in a sequence
- notably out of the ordinary; "the year saw one signal triumph for the Labour party"
- an electric quantity (voltage or current or field strength) whose modulation represents coded information about the source from which it comes
- any nonverbal action or gesture that encodes a message; "signals from the boat suddenly stopped" (同)signaling, sign
- any incitement to action; "he awaited the signal to start"; "the victory was a signal for wild celebration"
- (genetics) a combining of genes or characters different from what they were in the parents
- (physics) a combining of charges or transfer of electrons in a gas that results in the neutralization of ions; important for ions arising from the passage of high-energy particles
PrepTutorEJDIC
- (ある事実・状態・感情などの)『表れ』,印,気配,徴侯(indication);(…の)こん跡,計跡《+『of』+『名』》・『身ぶり』,手まね,合図 / 『標識』,看板 / (数学・音楽などの)記号 / (…の)『象徴』,シンボル(symbol)《+『of』+『名』》・《文》(…の)『前兆』,きざし《+『of』+『名』》・宮(きゅう)(黄道12区分の一つ) ・〈手紙・書類・作品など〉‘に'『署名する』・(…に)〈名前など〉‘を'書く《+『名』+『on』(『to』)+『名』》 / …‘を'雇う契約に署名する・…‘を'合図する,知らせる;…に合図する・署名する・契約書に署名して雇われる
- 〈U〉〈C〉(時間の上の,また因果関係のつながりによる)『連続』,続き / 〈C〉《a~》(…の)一連のもの《+『of』+『名』》 / 〈U〉(起こる)『順序』(order),筋道 / 〈C〉(…に対する)結果《+『to』+『名』》
- (警告・指示・情報などを伝える)『信号』,合図 / (…の)きっかけ,動機,導火線《+『for』+『名』》 / 〈人・車など〉‘に'『合図する』,信号を送る / …‘を'『合図』(信号)『で知らせる』 / 『合図する』,信号する / 合図の,信号の / めざましい,顕著な
- 配列,接続;(特に時間の)調整
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/15 10:25:29」(JST)
wiki en
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 複合免疫不全 combined immunodeficiencies
- 2. T-B-NK+ SCID：病因および遺伝学 t b nk scid pathogenesis and genetics
- 3. 免疫不全症を引き起こすCD3／T細胞受容体複合体疾患 cd3 t cell receptor complex disorders causing immunodeficiency
- 4. 不整脈の評価およびマネージメントにおける加算平均心電図の利用 use of the signal averaged electrocardiogram in arrhythmia evaluation and management
- 5. 成人における迅速導入気管挿管のための前処置剤 pretreatment agents for rapid sequence intubation in adults
English Journal
- Point mutation instability (PIN) mutator phenotype as model for true back mutations seen in hereditary tyrosinemia type 1 - a hypothesis.
- van Dyk E, Pretorius PJ.SourceCentre for Human Metabonomics, School for Physical and Chemical Sciences, North-West University, Potchefstroom Campus, Private Bag X6001, Potchefstroom, 2520, South Africa, Etresia.VanDyk@nwu.ac.za.
- Journal of inherited metabolic disease.J Inherit Metab Dis.2012 May;35(3):407-11. Epub 2011 Oct 15.
- Hereditary tyrosinemia type 1 (HT1) is an autosomal recessive disorder affecting fumarylacetoacetate hydrolase (FAH), the last enzyme in the tyrosine catabolism pathway. The liver mosaicism observed in HT1 patients is due to the reversion to the wild type of one allele of the original point mutation
- PMID 22002443
- Two mutations impair the stability and function of ubiquitin-activating enzyme (E1).
- Lao T, Chen S, Sang N.SourceDepartment of Biology and Graduate Program of Biological Sciences, College of Arts & Sciences, Drexel University, Philadelphia, Pennsylvania 19104, USA.
- Journal of cellular physiology.J Cell Physiol.2012 Apr;227(4):1561-8. doi: 10.1002/jcp.22870.
- Protein ubiquitination plays critical roles in the regulation of multiple cellular processes including cell proliferation, signal transduction, oncogenesis, and hypoxic response. TS20 is a Balb3T3-derived cell line in which ubiquitination is inhibited by restrictive temperature. While TS20 has been
- PMID 21678405
Japanese Journal
- 直接最適化法direct optimizationの問題点
- 吉澤 和徳
- タクサ : 日本動物分類学会誌 (30), 17-29, 2011-02-20
- … When the conserved regions contain only weak phylogenetic signal, then stochastic similarities within the variable regions strongly affect to the final alignment. … As a result, aligned variable sequences may provide superior amount of pseudo-signal which could even mask true weak signal contained in the conserved regions. …
- NAID 110008441101
- RAG-dependent recombination at cryptic RSSs within TEL–AML1 t(12;21)(p13;q22) chromosomal translocation region
- Numata Masashi,Saito Shoko,Nagata Kyosuke,沼田 和志,齋藤 祥子,永田 恭介
- Biochemical and biophysical research communications 402(4), 718-724, 2010-11-26
- … The recombination activating gene (RAG) is a lymphoid-specific endonuclease involved in the V(D)J recombination. … It has long been proposed that mis-targeting of RAG proteins is one of the factors contributing to lymphoid chromosomal translocation bearing authentic recombination signal sequences (RSSs) in immunoglobulin (Ig) and T cell receptor (TCR) gene loci or cryptic RSSs (cRSSs). …
- NAID 120002710217
Related Links
- The regional genes (V, D, J), used to generate T-cell receptors and Immunoglobulin molecules, are flanked by Recombination Signal Sequences ( RSSs) that are recognized by a group of enzymes known collectively as the VDJ recombinase.
- The regional genes (V, D, J) are flanked by Recombination Signal Sequences ( RSSs) that are recognized by a group of enzymes known collectively as the VDJ recombinase. RSSs are ...
Related Pictures
★リンクテーブル★
| リンク元 | 「再構成シグナル配列」「RSS」 |
| 拡張検索 | 「immunoglobulin J recombination signal sequence-binding protein」「recombination signal sequences」 |
| 関連記事 | 「sequence」「sign」「signaling」「sequencing」「signal」 |
「再構成シグナル配列」
- heptamer + spacer + nonamer
- heptamer
- 7bp:CACAGTG
- spacer
- 12bp or 23bp
- nonamer
- 9bp:ACAAAAACC
「RSS」
「immunoglobulin J recombination signal sequence-binding protein」
「recombination signal sequences」
「sequence」
- n.
- v.
- 配列決定する
- 関
- a sequence of、arrange、arrangement、array、barrage、consecutive、consequence、constellation、continually、continue、continuous、order、ordinal、outcome、output、product、result、resultant、sequencing、sequential、serial、series、thread
「sign」
- n.
「signaling」
- n.
「sequencing」
- n.
- 関
- sequence
「signal」
- n.