heparin-binding growth factor

線維芽細胞増殖因子

WordNet

1. cultivate by growing, often involving improvements by means of agricultural techniques; "The Bordeaux region produces great red wines"; "They produce good ham in Parma"; "We grow wheat here"; "We raise hogs here" (同)raise, farm, produce
2. come to have or undergo a change of (physical features and attributes); "He grew a beard"; "The patient developed abdominal pains"; "I got funny spots all over my body"; "Well-developed breasts" (同)develop, produce, get, acquire
3. become attached by or as if by the process of growth; "The tree trunks had grown together"
4. become larger, greater, or bigger; expand or gain; "The problem grew too large for me"; "Her business grew fast"
5. cause to grow or develop; "He grows vegetables in his backyard"
6. increase in size by natural process; "Corn doesnt grow here"; "In these forests, mushrooms grow under the trees"; "her hair doesnt grow much anymore"
7. (biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level; "he proposed an indicator of osseous development in children" (同)growing, maturation, development, ontogeny, ontogenesis
8. (pathology) an abnormal proliferation of tissue (as in a tumor)
9. a progression from simpler to more complex forms; "the growth of culture"
10. something grown or growing; "a growth of hair"
11. vegetation that has grown; "a growth of trees"; "the only growth was some salt grass"
12. be a contributing factor; "make things factor into a companys profitability"
13. any of the numbers (or symbols) that form a product when multiplied together
14. an independent variable in statistics
15. anything that contributes causally to a result; "a number of factors determined the outcome"
16. consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
17. resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
18. executed with proper legal authority; "a binding contract"
19. the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
20. strip sewn over or along an edge for reinforcement or decoration
21. the capacity to attract and hold something
22. an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
23. a concept whose truth can be proved; "scientific hypotheses are not facts"
24. a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
25. a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"

PrepTutorEJDIC

1. 『成長する』,育つ,〈植物が〉生える,茂る / (類・量・程などにおいて)『増大する』,大きくなる / 『しだいになる』 / …‘を'成長させる,大きくする,育てる / …から生じる(起こる)
2. 〈U〉(…の)『成長』,発育;『発達』,発展《+『of』+『名』》 / 〈U〉(数・量,重要性・力などの)『増加』,増大,拡張《+『of』+『名』》 / 〈U〉《修飾語[句]を伴って》栽培,生産,…産 / 〈C〉成育した物,(草,木,髪,ひげなどの)生えたもの / 〈C〉腫瘍(しゅよう)
3. (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
4. 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
5. 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行

UpToDate Contents

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• 1. インスリン様成長因子 Iの生理学 physiology of insulin like growth factor i
• 2. 血管新生阻害剤の概要 overview of angiogenesis inhibitors
• 3. 糸球体半月体形成の機序 mechanisms of glomerular crescent formation
• 4. 難治性狭心症マネージメントのための血管新生療法 therapeutic angiogenesis for management of refractory angina
• 5. 敗血症に対する治験剤および無効剤 investigational and ineffective therapies for sepsis

English Journal

• Psoriasin (S100A7) promotes stress-induced angiogenesis.

• Vegfors J1, Ekman AK1, Stoll SW2, Bivik Eding C1, Enerbäck C1.
• The British journal of dermatology.Br J Dermatol.2016 May 7. doi: 10.1111/bjd.14718. [Epub ahead of print]
• BACKGROUND: Vascular modifications occur early in the development of psoriasis and angiogenesis is one of the key features in the pathogenesis of the disease.OBJECTIVES: We aimed to identify the role of the S100 protein psoriasin in the angiogenesis associated with psoriasis.MATERIAL AND METHODS: Th
• PMID 27155199

• Growth factors-loaded stents modified with hyaluronic acid and heparin for induction of rapid and tight re-endothelialization.

• Choi DH1, Kang SN2, Kim SM1, Gobaa S3, Park BJ4, Kim IH5, Joung YK6, Han DK7.
• Colloids and surfaces. B, Biointerfaces.Colloids Surf B Biointerfaces.2016 May 1;141:602-10. doi: 10.1016/j.colsurfb.2016.01.028. Epub 2016 Jan 21.
• Rapid re-endothelialization of damaged vessel lining efficiently prevents restenosis and thrombosis and restores original vascular functions. In this study, we designed a novel metallic stent with a heparin-modified surface and used different methods, including 1-ethyl-3-(3-dimethylaminopropyl)carbo
• PMID 26928466

• Midkine Deteriorates Cardiac Remodeling via Epidermal Growth Factor Receptor Signaling in Chronic Kidney Disease.

• Honda Y1, Shishido T2, Takahashi T1, Watanabe T1, Netsu S1, Kinoshita D1, Narumi T1, Kadowaki S1, Nishiyama S1, Takahashi H1, Arimoto T1, Miyamoto T1, Kishida S1, Kadomatsu K1, Takeishi Y1, Kubota I1.
• Hypertension.Hypertension.2016 May;67(5):857-65. doi: 10.1161/HYPERTENSIONAHA.115.06922. Epub 2016 Mar 14.
• In chronic kidney disease, activation of the epidermal growth factor receptor (EGFR) leads to cardiac hypertrophy, which affects morbidity and mortality. In patients with renal insufficiency and heart failure, the expression of midkine, a heparin-binding growth factor, is increased. Therefore, we in
• PMID 26975703

Japanese Journal

• Crucial involvement of the CCL3-CCR5 axis-mediated fibroblast accumulation in colitis-associated carcinogenesis in mice

• Sasaki Soichiro,Baba Tomohisa,Shinagawa Kei,Matsushima Kouji,Mukaida Naofumi
• International Journal of Cancer 135(6), 1297-1306, 2014-09-15
• … This was associated with depressed expression of heparin-binding epidermal growth factor-like growth factor (HB-EGF), which is expressed mainly by fibroblasts. … They learned that CCL3 and its receptor, CCR5, gather up cancer-associated fibroblasts, which promote transformation and tumor growth. …
• NAID 120005463351

• ヘパリン結合性上皮成長因子様成長因子の刺激誘発による切断・放出への活性酸素種の関与

• 馬田 敏幸
• Journal of UOEH = 産業医科大学雑誌 36(2), 105-114, 2014-06-01
• NAID 40020126396

• Fibroblast Growth Factor-5 Participates in the Progression of Hepatic Fibrosis

• Hanaka Hiromi,Hamada Tsuyoshi,Ito Masataka,Nakashima Hiroyuki,Tomita Kengo,Seki Shuhji,Kobayashi Yasushi,Imaki Junko
• Experimental Animals 63(1), 85-92, 2014
• … Fibroblast growth factors (FGFs) are heparin-binding polypeptides with diverse biological activities in many developmental and metabolic processes. …
• NAID 130003391608

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★リンクテーブル★

リンク元	「線維芽細胞増殖因子」
関連記事	「binding」「grow」「fact」「factor」「growth」

「線維芽細胞増殖因子」

　　[★]

英

fibroblast growth factor, FGF

同

線維芽細胞成長因子, ヘパリン結合性増殖因子 heparin-binding growth factor HBGF

関

bFGF、FGFファミリー

種類

• fibroblast growth factor 1 FGF-1 acidic FGF
• fibroblast growth factor 2 FGF-2 basic FGF
• fibroblast growth factor 3 FGF-3
• fibroblast growth factor 7 FGF-7 Keratinocyte growth factor

「binding」

　　[★]

• n.

• 結合、バインディング

• adj.

• 結合性の

関

affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union

　 　 　 　 　

「grow」

　　[★]

• v.

(過去: grew-過去分詞: grown)

• 成長する、生育する、伸びる

関

extend、growth、outgrow、outgrowth、stretch

　 　 　 　 　 　 　

「fact」

　　[★]

• n.

• 事実、現状、実際、実態

関

actual、actually、in fact、in practice、indeed、practically

　 　 　 　 　

「factor」

　　[★]

• n.

• 因子、要因、要素、ファクター

関

element、elementary、factorial、parameter

　 　 　 　 　 　 　

「growth」

　　[★]

• n.

• 成長