- 関
- BACE、beta-secretase
WordNet
- to remain unmolested, undisturbed, or uninterrupted -- used only in infinitive form; "let her be"
- work in a specific place, with a specific subject, or in a specific function; "He is a herpetologist"; "She is our resident philosopher" (同)follow
- have life, be alive; "Our great leader is no more"; "My grandfather lived until the end of war" (同)live
- be identical to; be someone or something; "The president of the company is John Smith"; "This is my house"
- happen, occur, take place; "I lost my wallet; this was during the visit to my parents house"; "There were two hundred people at his funeral"; "There was a lot of noise in the kitchen"
- have the quality of being; (copula, used with an adjective or a predicate noun); "John is rich"; "This is not a good answer"
- occupy a certain position or area; be somewhere; "Where is my umbrella?" "The toolshed is in the back"; "What is behind this behavior?"
- spend or use time; "I may be an hour"
- serve in a specific professional capacity; "the priest sat for confession"; "she sat on the jury"
- be around, often idly or without specific purpose; "The object sat in the corner"; "We sat around chatting for another hour" (同)sit around
- be seated (同)sit_down
- be in session; "When does the court of law sit?"
- be located or situated somewhere; "The White House sits on Pennsylvania Avenue"
- stake on the outcome of an issue; "I bet $100 on that new horse"; "She played all her money on the dark horse" (同)wager, play
- the act of gambling; "he did it on a bet" (同)wager
- maintain with or as if with a bet; "I bet she will be there!" (同)wager
- the piece of land on which something is located (or is to be located); "a good site for the school" (同)land site
- physical position in relation to the surroundings; "the sites are determined by highly specific sequences of nucleotides" (同)situation
- second in order of importance; "the candidate, considered a beta male, was perceived to be unable to lead his party to victory"
- the 2nd letter of the Greek alphabet
- preliminary or testing stage of a software or hardware product; "a beta version"; "beta software"
PrepTutorEJDIC
- 《連結語として補語を伴なって…『である』,…だ,…です / 《位置・場所を表す語句を伴って》(…に)『ある』,いる(occupy a place or situation) / 〈物事が〉『存在する』,ある(exist);〈生物が〉生存する,生きている(live) / 行われる,起こる,発生する(take place, occur) / 存続する,そのままでいる(remain as before) / 《『be to』 do》 / …する予定である,…することになっている / …すべきだ / 《受動態の不定詞を伴って》…できる / 《命令》…するのだ / 《条件節に》…する意図がある / 《『if…were to』 do》…するとしたなら / 《『be』 do『ing』》《進行形》 / 《進行中の動作》…している,しつつある / 《近い未来》…しようとしている,するつもり / 《動作の反復》(いつも)…している / 《『be』+『他動詞の過去分詞』》《受動態》…される,されている / 《『be』+『自動詞の過去分詞』》《完了形》…した[状態にある]
- (…に)『座る』,座っている《+『at』(『on, in』)+『名』》・着席する《+『down』》・(…に)〈鳥などが〉『止まる』,休む《+『on』+『名』》・〈めんどりが〉卵を抱く,巣に就く / 《場所の副詞[句]を伴って》(ある場所に)『位置する』・ (画家・写真家のために)ポーズをとる・しっとしている,動かないでいる・(議員・委員などの)職に就いている《+『on』+『名』》・〈議会・法廷などが〉開会(開廷)される・(…に)負担となる,重荷となる《+『on』(『upon』)+『名』》・〈衣服などが〉(…に)合う,似合う《+『on』+『名』》・〈人〉‘を'座らせる,着席させる《+『down』+『名,』+『名』+『down』》・〈馬〉‘に'乗る・《英》〈試験〉‘を'受ける
- 『かけ』・(…との)かけ《+『with』+『名』》 / かけた物(金) / かけの対象 / 〈金・物〉'を'『かける』 / (かけ事・ゲームなどで)〈人〉‘と'『かけをする』《+『名』〈人〉+『on』+『名』》 / (…に)『かける』《+『on』(『against』)+『名』(one's do『ing』)》
- (町・建物などの)『場所』;敷地,用地 / 遺跡;(事件などの)現場 / 〈建物など〉‘を'位置させる(locate)
- ベータ(ギリシア語アルファベットの第2文字;B,β;英語のB,b に遭当)
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Exercise decreases BACE and APP levels in the hippocampus of a rat model of Alzheimer's disease.
- Alkadhi KA1, Dao AT2.
- Molecular and cellular neurosciences.Mol Cell Neurosci.2018 Jan;86:25-29. doi: 10.1016/j.mcn.2017.11.008. Epub 2017 Nov 9.
- PMID 29128320
- Structure Related Inhibition of Enzyme Systems in Cholinesterases and BACE1 In Vitro by Naturally Occurring Naphthopyrone and Its Glycosides Isolated from Cassia obtusifolia.
- Shrestha S1, Seong SH2, Paudel P3, Jung HA4, Choi JS5.
- Molecules (Basel, Switzerland).Molecules.2017 Dec 28;23(1). pii: E69. doi: 10.3390/molecules23010069.
- PMID 29283428
- Toluidine blue O modifies hippocampal amyloid pathology in a transgenic mouse model of Alzheimer's disease.
- Yuksel M1, Biberoglu K2, Onder S2, Akbulut KG3, Tacal O4.
- Biochimie.Biochimie.2017 Dec 14. pii: S0300-9084(17)30334-6. doi: 10.1016/j.biochi.2017.12.004. [Epub ahead of print]
- PMID 29248542
Japanese Journal
- Mercury-induced amyloid-beta (Aβ) accumulation in the brain is mediated by disruption of Aβ transport
- Beta-site APP cleaving enzyme 1 (BACE1) is increased in remaining neurons in Alzheimer's disease brains
- Neuroscience research : the official journal of the Japan Neuroscience Society 54(1), 24-29, 2006-01-01
- NAID 10020614044
Related Links
- BACE（ベース）[beta-site APP cleaving enzyme]とは。意味や解説、類語。《beta-site APP cleaving enzyme》⇒βセクレターゼ - goo国語辞書は30万2千件語以上を収録。政治・経済・医学・ITなど、最新用語の追加も定期
- Beta-site APP cleaving enzyme 1 (BACE1) and γ secretase are two aspartyl proteases that cleave amyloid precursor protein (APP), and increase A β -40/42 peptide fragments [ 3, 6 ]. BACE1 catalyzes the rate-limiting step in the generation of A β peptide [ 7 ]. Multiple factors that are associated with BACE1 increase AD incidence [ 2 ].
- Bace2 beta-site APP-cleaving enzyme 2 [ (house mouse)] This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein undergoes proteolytic processing to generate an active endopeptidase enzyme.
★リンクテーブル★
[★]
- 英
- beta-secretase、beta-site APP cleaving enzyme、BACE
- 関
- セクレターゼ、アミロイド前駆体タンパク質βサイト切断酵素、γセクレターゼ、アミロイド前駆タンパク質分泌酵素、β-セクレターゼ、αセクレターゼ
[★]
βセクレターゼ
- 関
- alpha-secretase、amyloid precursor protein secretase、BACE、beta-site APP cleaving enzyme、gamma-secretase、secretase
[★]
- 関
- beta-secretase、beta-site APP cleaving enzyme
[★]
- 英
- beta-site APP cleaving enzyme、BACE
- 関
- βセクレターゼ
[★]
[★]
[★]
- 関
- lie、locate、location、loci、locus、map、position、rank、seat、situated、situation、stand、topo
[★]
- 関
- location、loci、locus、place、topo
[★]