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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/06 23:01:01」(JST)
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2-Aminopurine
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Names |
IUPAC name
9H-purin-2-amine
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Identifiers |
CAS Registry Number
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452-06-2 N |
ChEBI |
CHEBI:479072 Y |
ChEMBL |
ChEMBL388594 Y |
ChemSpider |
9561 Y |
InChI
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InChI=1S/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10) Y
Key: MWBWWFOAEOYUST-UHFFFAOYSA-N Y
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InChI=1/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10)
Key: MWBWWFOAEOYUST-UHFFFAOYAC
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Jmol-3D images |
Image |
PubChem |
9955 |
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Properties |
Chemical formula
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C5H5N5 |
Molar mass |
135.13 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N verify (what is: Y/N?) |
Infobox references |
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2-Aminopurine, an analog of guanine and adenine, is a fluorescent molecular marker used in nucleic acid research.[1] It most commonly pairs with thymine as an adenine-analogue, but can also pair with cytosine as a guanine-analogue;.[2] For this reason it is sometimes used in the laboratory for mutagenesis.
See also
References
- ^ Jean JM, Hall KB (2001). "2-Aminopurine fluorescence quenching and lifetimes: role of base stacking". Proc. Natl. Acad. Sci. U.S.A. 98 (1): 37–41. doi:10.1073/pnas.011442198. PMC 14540. PMID 11120885.
- ^ Sowers LC, Fazakerley GV, Eritja R, Kaplan BE, Goodman MF (1986). "Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR". Proc. Natl. Acad. Sci. U.S.A. 83 (15): 5434–5438. doi:10.1073/pnas.83.15.5434. PMC 386301. PMID 3461441.
English Journal
- Mode of DNA binding with γ-butyrolactone receptor protein CprB from Streptomyces coelicolor revealed by site-specific fluorescence dynamics.
- Biswas A1, Narayan S2, Kallianpur MV2, Krishnamoorthy G3, Anand R4.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 Nov;1850(11):2283-92. doi: 10.1016/j.bbagen.2015.08.008. Epub 2015 Aug 14.
- BACKGROUND: The γ-butyrolactone (GBL) binding transcription factors in Streptomyces species are known for their involvement in quorum sensing where they control the expression of various genes initiating secondary metabolic pathways. The structurally characterized member of this family CprB from St
- PMID 26278022
- Site-Selective Monitoring of the Interaction of the SRA Domain of UHRF1 with Target DNA Sequences Labeled with 2-Aminopurine.
- Greiner VJ1, Kovalenko L1,2, Humbert N1, Richert L1, Birck C3, Ruff M3, Zaporozhets OA2, Dhe-Paganon S4, Bronner C1,3, Mély Y1.
- Biochemistry.Biochemistry.2015 Sep 30. [Epub ahead of print]
- UHRF1 plays a central role in the maintenance and transmission of epigenetic modifications by recruiting DNMT1 to hemimethylated CpG sites via its SET and RING-associated (SRA) domain, ensuring error-free duplication of methylation profiles. To characterize SRA-induced changes in the conformation an
- PMID 26368281
- Label-free detection of Phytophthora ramorum using surface-enhanced Raman spectroscopy.
- Yüksel S1, Schwenkbier L, Pollok S, Weber K, Cialla-May D, Popp J.
- The Analyst.Analyst.2015 Sep 22. [Epub ahead of print]
- In this study, we report on a novel approach for the label-free and species-specific detection of the plant pathogen Phytophthora ramorum from real samples using surface enhanced Raman scattering (SERS). In this context, we consider the entire analysis chain including sample preparation, DNA isolati
- PMID 26393411
Japanese Journal
- Agrobacterium-mediated transformation and regeneration of Freesiahybrida
- Uwagaki Yohei,Matsuda Eriko,Komaki Masako,Murahama Minoru,Otani Motoyasu,Nishizawa Naoko,Hamada Tatsuro
- Plant Biotechnology 32(2), 165-168, 2015
- … Hygromycin-resistant lines of both cultivars regenerated into plantlets after transfer onto MS medium containing 2 mg l−1 3-indoleacetic acid and 3 mg l−1 6-benzyl aminopurine and/or plant growth regulator-free MS medium. …
- NAID 130005085990
- Agrobacterium-mediated Transformation and Regeneration of Freesiahybrida
- Uwagaki Yohei,Matsuda Eriko,Komaki Masako,Murahama Minoru,Otani Motoyasu,Nishizawa Naoko,Hamada Tatsuro
- Plant Biotechnology advpub(0), 2015
- … Hygromycin-resistant lines of both cultivars regenerated into plantlets after transfer onto MS medium containing 2 mg l−1 3-indoleacetic acid and 3 mg l−1 6-benzyl aminopurine and/or plant growth regulator-free MS medium. …
- NAID 130005066011
- ベンジルアミノプリン処理による秋ギクの腋芽形成に及ぼす影響
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